Needle-Shaped Biosensors for Precision Diagnoses: From Benchtop Development to In Vitro and In Vivo Applications DOI Creative Commons

Ruier Xue,

Fei Deng, Tianruo Guo

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(8), P. 391 - 391

Published: Aug. 13, 2024

To achieve the accurate recognition of biomarkers or pathological characteristics within tissues cells, in situ detection using biosensor technology offers crucial insights into nature, stage, and progression diseases, paving way for enhanced precision diagnostic approaches treatment strategies. The implementation needle-shaped biosensors (N-biosensors) presents a highly promising method conducting measurements clinical various organs, such as brain spinal cord. Previous studies have highlighted excellent performance different N-biosensor designs detecting from samples vitro. Recent preclinical vivo also shown significant progress translation biomarker detection, enabling diagnoses cancer, diabetes, infectious diseases. This article begins with an overview current state-of-the-art benchtop designs, discusses their applications sensitive diagnoses, concludes by exploring challenges potential avenues next-generation technology.

Language: Английский

Review on Healthcare Biosensing Nanomaterials DOI
Alok Tripathi, José Bonilla‐Cruz

ACS Applied Nano Materials, Journal Year: 2023, Volume and Issue: 6(7), P. 5042 - 5074

Published: March 31, 2023

Fast technological progress has sped up the growth of telemedicine, mobile e-health services, and healthcare monitoring, which, nowadays, are technologies in high demand medical field analytical sensing. Biosensing device design promoted forefront research topics wherein new sensing have been developed. In this regard, nanomaterials had a crucial role novel biosensors based on emerged as detective tools for several biomolecules. Most remarkably sensitive selective to detect cancer biomarkers, toxins foods, drugs, pathogenic microorganisms, cholesterol, pesticides, nucleic acids, glucose, heavy-metal contaminations, other bioanalytes under different platforms at extraordinarily low concentrations (nanomolar, picomolar, or femtomolar). A comprehensive review used biosensing is offered herein. Specifically, offers point view, highlighting covering exhaustively kinds (<500 nm) human diseases through biosensing. sense, we organize them into organic, inorganic, carbon-based, thus offering guide selecting best nanomaterial specific detection. Further, it provides roadmap real-time utilization commercial scale. Also, addresses some aspects use applications The discussed paper highlights immense potential implement nanocomposites initial examination point-of-care testing.

Language: Английский

Citations

56

Graphene and its derivatives (GO, rGO and GQD): a comprehensive review of their role in combating COVID-19 DOI Creative Commons
Spandan Guha, Shanta Chakrabarty

Advances in Physics X, Journal Year: 2025, Volume and Issue: 10(1)

Published: Jan. 15, 2025

The COVID-19 pandemic has ignited a search for innovative solutions to tackle viral transmission and ensure early detection. Graphene its derivatives have emerged as promising materials in this fight, showcasing impressive potential across diverse range of applications. From frontline defenses like antiviral PPE with enhanced filtration breathability microscopic detective work via highly sensitive FET biosensors, graphene offers multifaceted attack on the SARS-CoV-2 virus. Its impact extends beyond diagnostics, empowering energy storage disinfection technologies while revolutionizing drug delivery air purification through virus-capturing filters. Antiviral coatings vigilant nano-sensors further bolster arsenal, offering comprehensive protection at surface levels. Moreover, graphene-based masks, their reduce pollution exposure, may even offer an additional layer against polluted areas. In summary, emerges versatile guardian COVID-19, poised revolutionize fight beyond. applications, coupled ongoing research, paint compelling picture future where one atom time, rewrites narrative defense.

Language: Английский

Citations

1

Chemical engineering innovations in nanoparticle-based biosensors for enhanced detection of biological molecules DOI
V. Ramkumar, A. Bharathi, Mayakrishnan Gopiraman

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: 507, P. 160081 - 160081

Published: Jan. 31, 2025

Language: Английский

Citations

1

Hierarchical Nanobiosensors at the End of the SARS-CoV-2 Pandemic DOI Creative Commons

Jael Abigail Medrano-Lopez,

I. Villalpando, Ma. Isabel Salazar

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(2), P. 108 - 108

Published: Feb. 18, 2024

Nanostructures have played a key role in the development of different techniques to attack severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Some applications include masks, vaccines, and biosensors. The latter are great interest for detecting diseases since some their features allowed us find specific markers secretion samples such as saliva, blood, even tears. Herein, we highlight how hierarchical nanoparticles integrated into two or more low-dimensional materials present outstanding advantages that attractive photonic biosensing using nanoscale functions. potential nanohybrids with superlative mechanical characteristics together optical optoelectronic properties is discussed. progress scientific research focused on variety viruses has become medical milestone recent years, laid groundwork future disease treatments. This perspective analyzes crucial information about use nanostructures prevention, treatment, mitigation SARS-CoV-2 effects.

Language: Английский

Citations

8

Recent Advances in Electrochemical and Nanophotonic Biosensors for SARS-CoV-2 Detection DOI Creative Commons
Yeon Kyung Lee, Hyun Seok Song

BioChip Journal, Journal Year: 2024, Volume and Issue: 18(2), P. 171 - 185

Published: March 8, 2024

The contagious respiratory illness coronavirus disease 2019 (COVID-19) has had an unprecedented impact on both global health and society, causing a pandemic due to its rapid transmission. emergence of numerous variants severe acute syndrome 2 (SARS-CoV-2) underscores the critical importance accurately diagnosing concern (VOCs). Viruses have demonstrated remarkable ability evolve adapt their environments. Therefore, it is crucial develop effective diagnostic methods that provide rapid, high sensitivity, selectivity in point-of-care (PoC) format, meeting vital need for detecting addressing emerging new viruses future. With development nanotechnology biotechnology, there been innovations multiplexed, portable sensors with sensitivity specificity. In this review, we discuss fundamental properties SARS-CoV-2 virus, conventional methods, recent developments from perspective electrochemical- nanophotonic-based biosensors, including our work.

Language: Английский

Citations

7

A dual-mode sensor based on surface molecularly imprinted Pt nanoclusters for detection of SARS-CoV-2 spike protein DOI
Yang Xu,

Zhouyi Yu,

Zheng‐Zhi Yin

et al.

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 415, P. 136020 - 136020

Published: May 24, 2024

Language: Английский

Citations

7

Sensitive and rapid detection of influenza A virus for disease surveillance using dual-probe electrochemical biosensor DOI
Jianhua Yan, Cheng Qian, Hongjie Liu

et al.

Bioelectrochemistry, Journal Year: 2023, Volume and Issue: 153, P. 108497 - 108497

Published: June 28, 2023

Language: Английский

Citations

16

A surface molecularly imprinted electrochemical biosensor for the detection of SARS-CoV-2 spike protein by using Cu7S4-Au as built-in probe DOI Open Access

Zheng‐Zhi Yin,

Zixuan Liu, Min Zhou

et al.

Bioelectrochemistry, Journal Year: 2023, Volume and Issue: 152, P. 108462 - 108462

Published: May 10, 2023

Language: Английский

Citations

12

An electrochemical microbiosensor for serotonin based on surface imprinted layer coordinated bimetal functionalized acupuncture needle DOI

Shanshan Zhan,

Jiayi Zhang,

Chunrong Gao

et al.

Talanta, Journal Year: 2024, Volume and Issue: 277, P. 126334 - 126334

Published: May 29, 2024

Language: Английский

Citations

4

Synthesis of chiral graphene structures and their comprehensive applications: a critical review DOI
Animesh Sinha, Hongyun So

Nanoscale Horizons, Journal Year: 2024, Volume and Issue: 9(11), P. 1855 - 1895

Published: Jan. 1, 2024

Chiral graphene, a “superlattice structure,” effectively engages with target substances. Its superconductivity, tunable electronic structure, and topological states could significantly contribute to advanced materials science technologies.

Language: Английский

Citations

4