Biomimetic CuCoO2 nanosheets reinforced with self-assembling peptide nanofibers for tumor photothermal therapy DOI Creative Commons
Mingjin Xu,

Youyin Xu,

Chenxi Du

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(53), P. 39163 - 39172

Published: Jan. 1, 2024

The flexible design and unique physical chemical properties of self-assembled peptides have shown great potential for applications in the fields materials science, life environmental science. Peptide nanofibers (PNFs), as a kind bioactive nanomaterials, possess excellent biocompatibility, designability, multifaceted functionalizability. In this work, we describe PNFs that by peptide molecules carriers bimetallic nanosheets (BMNS), leading to development hybrid BMNS-PNFs, with properties. BMNS-PNFs exhibit photothermal conversion efficiency (PCE) up 31.57%, can be used nanoplatform therapy (PTT) lung tumour cells. Through results, it is reduce cytotoxicity cancer cell killing effects, rates more than 95% 90% cells HCC2279 PC9, respectively. Finally, comprehensive PTT performance analysed Ranking Efficiency Performance (REP), REP value calculated 0.741. sequences assemble into study are instructive functional structural modulation molecular self-assembly, constructed bimetallic-biomolecular provide strategy medical bioengineering.

Language: Английский

Self-assembled nanoprobes for cancer phototheranostics DOI
Sondavid Nandanwar,

Van Kieu Thuy Nguyen,

Dai Lam Tran

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 538, P. 216643 - 216643

Published: April 18, 2025

Language: Английский

Citations

0

A cancer theranostic nanoplatform for second near-infrared fluorescence imaging-guided carbon monoxide-sensitized mild photothermal therapy with ICD induction DOI

Shaoyan Gan,

Xiuli Wen,

Li Li

et al.

Journal of Colloid and Interface Science, Journal Year: 2025, Volume and Issue: 693, P. 137652 - 137652

Published: April 19, 2025

Language: Английский

Citations

0

Bioengineered nanomaterials for dynamic diagnostics in vivo DOI
Jizhong Wu, Xinyu Zhou, Chung Yin Tsang

et al.

Chemical Society Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

By integrating four energy modalities—NIR light, radiation, magnetic field, and ultrasound—with bioengineered nanomaterials, dynamic in vivo diagnostics can be achieved, advancing the path toward personalized precision medicine.

Language: Английский

Citations

0

Organic Nanomaterials Based on Aza-Boron Dipyrromethene with Aggregation-Induced Emission for NIR-II Fluorescence Imaging-Guided Photothermal Therapy DOI
Jiaming Chen,

Qilong Sha,

Muneeb Ur Rehman

et al.

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 29, 2024

Language: Английский

Citations

2

Dimethylamino-Functionalized BODIPY Nanoparticle Enhances Near-Infrared Fluorescence Imaging and Photothermal Therapy DOI
Xin Wang, Xingyu Zhao, Huixuan Qi

et al.

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: 7(22), P. 26077 - 26085

Published: Nov. 2, 2024

Organic dyes have been widely used in bioimaging, molecular probes, imaging vivo, and phototherapy. However, it is still a major challenge to improve the therapeutic properties of organic dyes. In this work, boron dipyrromethene (BODIPY) nanoparticles (NPs) were synthesized with poly(ethylene glycol)2k-block-poly(d,l-lactide)2k (PEG–PLA) NPs for tumor microenvironment response, near-infrared fluorescence (NIRF) high signal-to-noise ratio (SNR), photothermal therapy (PTT). The absorption spectra obtained BDP changed as pH decreased. introduction dimethylamino group enhanced conversion efficiency capability BODIPY-loaded PEG–PLA (BDP NPs). After injection into mice, these showed excellent efficacy toward hepatoma papillary thyroid cancer. Additionally, could be NIRF SNR after BODIPY was modified group. This work highlights that engineering can enhance luminescence are theranostic agents.

Language: Английский

Citations

1

A tumor Microenvironment-triggered protein-binding Near-infrared-II Theranostic nanoplatform for Mild-Temperature photothermal therapy DOI

Wenlong Huang,

Bo Jin,

Huili Gong

et al.

Journal of Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 680, P. 375 - 388

Published: Nov. 9, 2024

Language: Английский

Citations

1

Dual‐Responsive and Aggregation‐Induced‐Emission Probe for Selective Imaging of Infectious Urolithiasis DOI
Xiangyu Li, Qi Wang, Shanshan Hu

et al.

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(28)

Published: May 31, 2024

Identifying infected stones is crucial due to their rapid growth and high recurrence rate. Here, the calcium-magnesium dual-responsive aggregation-induced emission (AIE)-active probe TCM-5COOH (Tricyano-methlene-pyridine-5COOH), distinctively engineered distinguish high-threat infection calculi from metabolic stones, presented. Upon incorporation of flexible alkyl carboxyl group, featuring five moieties demonstrates excellent water solubility enhanced penetration into porous infectious stones. The robust chelation with stone surface-abundant Ca

Language: Английский

Citations

0

Biomimetic CuCoO2 nanosheets reinforced with self-assembling peptide nanofibers for tumor photothermal therapy DOI Creative Commons
Mingjin Xu,

Youyin Xu,

Chenxi Du

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(53), P. 39163 - 39172

Published: Jan. 1, 2024

The flexible design and unique physical chemical properties of self-assembled peptides have shown great potential for applications in the fields materials science, life environmental science. Peptide nanofibers (PNFs), as a kind bioactive nanomaterials, possess excellent biocompatibility, designability, multifaceted functionalizability. In this work, we describe PNFs that by peptide molecules carriers bimetallic nanosheets (BMNS), leading to development hybrid BMNS-PNFs, with properties. BMNS-PNFs exhibit photothermal conversion efficiency (PCE) up 31.57%, can be used nanoplatform therapy (PTT) lung tumour cells. Through results, it is reduce cytotoxicity cancer cell killing effects, rates more than 95% 90% cells HCC2279 PC9, respectively. Finally, comprehensive PTT performance analysed Ranking Efficiency Performance (REP), REP value calculated 0.741. sequences assemble into study are instructive functional structural modulation molecular self-assembly, constructed bimetallic-biomolecular provide strategy medical bioengineering.

Language: Английский

Citations

0