Nanotechnology and COVID-19: Prevention, diagnosis, vaccine, and treatment strategies

Frontiers in Materials, Journal Year: 2023, Volume and Issue: 9

Published: Jan. 11, 2023

In December 2019, Coronavirus pandemic (COVID-19) caused by Severe Acute Respiratory Syndrome 2 (SARS-CoV-2) viruses, which affected the whole world, is emerged. The details on epidemiology, infection source, transmission mode, and prognosis of SARS-CoV-2 gave in this review. Universal control standards such as hand hygiene, environmental cleanliness, use personal protective equipment, quarantine used to prevent spread COVID-19 without vaccine. However, many vaccine candidate studies carried out globally with using traditional technological approaches. Innovations technology allow development nanotechnological tools formation systems that will inactivate patients. It expected include technologies combine different disciplines, especially robotic applications, antimicrobial nanotechnology, tissue engineering for future treatment COVID-19. This review-based work discusses relationship nanotechnology based working principles.

Language: Английский

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Estimation of Anti-SARS-CoV-2 IgM/IgG Seroprevalence Among Non-Vaccinated and Vaccinated University Students: A Cross-Sectional Egyptian Study

Viruses, Journal Year: 2025, Volume and Issue: 17(3), P. 378 - 378

Published: March 6, 2025

It is essential to comprehend the humoral immune response severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its vaccines maximize effectiveness of anti-SARSCoV-2 community immunization efforts. The aim this cross-sectional study was determine seroprevalence anti-SARS-CoV-2 IgM/IgG among newcomer students at Kafr Elsheikh University in Egypt, whether they had been vaccinated or not. Blood samples from 400 healthy (200 non-vaccinated 200 vaccinated) were evaluated for presence using colloidal gold immunochromatography lateral flow immunoassay cards, then results confirmed by specific ELISA tests. prevalence antibodies participants (n = 400) 56.3% IgG 13.3% IgM. Regarding participants, 55.0% females, mean age 18.2 years, BMI 25.35. 58.5% 18.1 25.3. There statistically non-significant correlations (p ˃ 0.05) between gender, BMI, each IgM- IgG-positivity both groups. In total, 41.5% 48.5% IgM-positive IgG-positive non-vaccinated, respectively. Furthermore, 51.5% vaccinated, No significant association immunoglobulins positivity immunological nonsmokers, people who exercise regularly, those take vitamin supplements, eat a balanced diet, use certain herbs noteworthy. Among subjects, 96.6%, 25.0%, 31.9%, 45.7%, 7.8% group, versus 97.2%, 60.6%, 64.2%, 52.3%, 6.4% exercisers, taking eating herbs, 93.5%, 32.3%, 35.5%, 48.4%, 6.5% 100.0%, 63.6%, 81.8%, 45.5%, 4.5% physical supplement users, eaters, herbalists, Persons are free comorbidities, young, non-obese, non-smokers, engage exercise, vitamins, immunostimulant herbal all have strong response, even if not vaccinated. During pandemics, vaccination group should be priority preserve vaccine doses high-risk vulnerable people. Even there lockdown during an anticipated future epidemic pandemic, we prioritize lifestyle choices, along with increasing activity.

Language: Английский

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Dental Healthcare Amid the COVID-19 Pandemic

International Journal of Environmental Research and Public Health, Journal Year: 2021, Volume and Issue: 18(21), P. 11008 - 11008

Published: Oct. 20, 2021

The hustle and bustle of the planet Earth have come to a halt thanks novel coronavirus. virus has affected approximately 219 million people globally; taken lives 4.55 patients as September 2021; created an ambiance fear, social distancing, economic instability. purpose this review article is trace historical origin evolution severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2). highly contagious with unique feature rapid mutations—the scientific research paving way for discoveries regarding disease (COVID-19) diagnosis, features, prevention, vaccination. connections between pandemic dental practices are essential because COVID-19 transmitted by aerosols, fomites, droplets, which also produced during procedures, putting both patient dentist at risk. main emphasis paper highlight psychological, economic, impact on throughout world under what circumstances guidelines can health care be provided. In current situation pandemic, appropriate screening tool must established either using molecular testing or saliva point-of-care technology, will effective in identifying well isolating potential contacts carriers hopes contain mitigate infection. blessing disguise that united leaders, scientists, providers, all professions from around fight against common enemy.

Language: Английский

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Review: A systematic review of virus-like particles of coronavirus: Assembly, generation, chimerism and their application in basic research and in the clinic

International Journal of Biological Macromolecules, Journal Year: 2022, Volume and Issue: 200, P. 487 - 497

Published: Jan. 19, 2022

Language: Английский

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Comprehensive role of SARS‐CoV‐2 spike glycoprotein in regulating host signaling pathway

Journal of Medical Virology, Journal Year: 2022, Volume and Issue: 94(9), P. 4071 - 4087

Published: April 30, 2022

Since the outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome 2 (SARS-CoV-2) infection, global public health and economy have suffered unprecedented damage. Based on increasing related literature, characteristics pathogenic mechanisms virus, epidemiological clinical features are being rapidly discovered. The spike glycoprotein (S protein), as a key antigen SARS-CoV-2 for developing vaccines, antibodies, drug targets, has been shown to play an important role in viral entry, tissue tropism, pathogenesis. In this review, we summarize molecular interaction between S protein host factors, especially receptor-mediated modulation signaling pathways, highlight progression potential therapeutic prophylactic agents prevention treatment infection.

Language: Английский

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