Research Trends and Dynamics in Single-cell RNA Sequencing for Musculoskeletal Diseases: A Scientometric and Visualization Study
International Journal of Medical Sciences,
Journal Year:
2025,
Volume and Issue:
22(3), P. 528 - 550
Published: Jan. 1, 2025
Background:
Worldwide,
approximately
1.7
billion
people
are
afflicted
with
musculoskeletal
(MSK)
diseases,
posing
significant
health
challenges.
The
introduction
of
single-cell
RNA
sequencing
(scRNA-seq)
technology
provides
novel
insights
and
approaches
to
comprehend
the
onset,
progression,
treatment
MSK
diseases.
Nevertheless,
there
is
a
remarkable
lack
analytical
descriptive
studies
regarding
trajectory,
essential
research
directions,
current
situation,
pivotal
focuses,
upcoming
perspectives.
Therefore,
aim
this
present
comprehensive
overview
advancements
made
in
scRNA-seq
for
disorders
over
past
15
years.
Methods:
It
utilizes
robust
dataset
derived
from
Web
Science
Core
Collection,
encompassing
January
1,
2009,
through
September
6,
2024.
To
achieve
this,
advanced
methodologies
were
applied
conduct
thorough
scientometric
visual
analyses.
Results:
findings
underscore
preeminent
role
China,
which
contributes
63.49%
total
publications,
thereby
exerting
substantial
impact
within
domain.
Notable
contributions
came
institutions
such
as
Shanghai
Jiao
Tong
University,
Sun
Yat-sen
Harvard
Medical
School,
Liu
Yun
being
leading
contributor.
Frontiers
Immunology
published
greatest
number
papers
field.
This
study
identified
joint
bone
neoplasms,
fractures,
intervertebral
disc
degeneration
main
focuses.
Conclusion:
extensive
analysis
benefits
both
experienced
novice
researchers
by
facilitating
immediate
access
critical
data,
fostering
innovation
Language: Английский
Impact of Metabolites from Foodborne Pathogens on Cancer
Foods,
Journal Year:
2024,
Volume and Issue:
13(23), P. 3886 - 3886
Published: Dec. 1, 2024
Foodborne
pathogens
are
microorganisms
that
cause
illness
through
contamination,
presenting
significant
risks
to
public
health
and
food
safety.
This
review
explores
the
metabolites
produced
by
these
pathogens,
including
toxins
secondary
metabolites,
their
implications
for
human
health,
particularly
concerning
cancer
risk.
We
examine
various
such
as
Salmonella
sp.,
Campylobacter
Escherichia
coli,
Listeria
monocytogenes,
detailing
specific
of
concern
carcinogenic
mechanisms.
study
discusses
analytical
techniques
detecting
chromatography,
spectrometry,
immunoassays,
along
with
challenges
associated
detection.
covers
effective
control
strategies,
processing
techniques,
sanitation
practices,
regulatory
measures,
emerging
technologies
in
pathogen
control.
manuscript
considers
broader
highlighting
importance
robust
policies,
awareness,
education.
identifies
research
gaps
innovative
approaches,
recommending
advancements
detection
methods,
preventive
policy
improvements
better
manage
foodborne
metabolites.
Language: Английский
Wearable Aptasensors
Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
96(49), P. 19160 - 19182
Published: Nov. 27, 2024
This
Perspective
explores
the
revolutionary
advances
in
wearable
aptasensor
(WA)
technology,
which
combines
devices
and
aptamer-based
detection
systems
for
personalized,
real-time
health
monitoring.
The
leverage
specificity
sensitivity
of
aptamers
to
target
specific
molecules,
offering
broad
applications
from
continuous
glucose
tracking
early
diagnosis
diseases.
integration
data
analytics
artificial
intelligence
(AI)
allows
risk
prediction
guides
preventive
measures.
While
challenges
miniaturization,
power
efficiency,
security
persist,
these
hold
significant
potential
democratize
healthcare
reshape
patient-doctor
interactions.
Language: Английский
Editorial Perspective: Advancements in Microfluidics and Biochip Technologies
Micromachines,
Journal Year:
2025,
Volume and Issue:
16(1), P. 77 - 77
Published: Jan. 11, 2025
Microfluidics
and
biochip
technologies
continue
to
play
a
key
role
in
driving
innovation
across
biomedical,
environmental
engineering
disciplines
[...]
Language: Английский
Unraveling the future: hot topics shaping molecular diagnostics Today
Expert Review of Molecular Diagnostics,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 16, 2025
This
special
report
highlights
the
transformative
potential
of
advanced
diagnostic
technologies
in
modern
healthcare,
emphasizing
their
role
enhancing
disease
detection,
treatment
personalization,
and
patient
outcomes.
Innovations
such
as
Next-Generation
Sequencing
(NGS),
liquid
biopsy,
Clustered
Regularly
Interspaced
Short
Palindromic
Repeats
(CRISPR)
-based
diagnostics,
Point-of-Care
(PoC)
testing,
microbiome
analysis,
Artificial
Intelligence
are
reshaping
landscape.
These
methods
facilitate
early
identification
diseases,
enable
tailored
therapies
based
on
individual
genetic
profiles,
provide
noninvasive
monitoring
options.
Furthermore,
telemedicine
enhances
access
to
care
while
reducing
costs
associated
with
traditional
healthcare
delivery.
Despite
these
advancements,
challenges
remain
regarding
regulatory
compliance,
data
privacy
concerns,
disparities
services.
The
underscores
need
for
ongoing
collaboration
among
stakeholders
address
limitations
effectively.
By
prioritizing
equitable
continuously
evaluating
emerging
technologies'
impact
safety
health
outcomes,
system
can
harness
full
diagnostics
improve
global
health.
Language: Английский
Harnessing artificial intelligence for theragnostic applications: Current landscape and future directions
Arundhati Pande,
No information about this author
Abhishek Kumar,
No information about this author
Ashish Anjankar
No information about this author
et al.
Multidisciplinary Reviews,
Journal Year:
2025,
Volume and Issue:
8(7), P. 2025218 - 2025218
Published: Feb. 7, 2025
In
the
area
of
theragnostics,
use
artificial
intelligence
(AI)
is
supporting
personalised
medicine
methods
that
merge
therapeutic
and
diagnostic
techniques,
which
causing
sector
to
undergo
a
transition.
An
analysis
historical
backdrop,
current
condition,
promise
intelligence-enhanced
theragnostic
systems
presented
in
this
article.
We
investigate
underlying
ideas
intelligence,
such
as
machine
learning,
deep
neural
networks,
well
their
applications
variety
medical
fields,
including
cancer,
pathology,
imaging,
cardiology,
hypertension
control,
diabetes
management.
The
ability
integrate
wide
information,
recognise
trends,
enable
real-time
decision-making
patient
monitoring
all
illustrate
competency.
It
possible
digital
twins,
make
adaptive
learning
algorithms
dynamic
virtual
models,
might
be
used
optimise
treatment
regimens
anticipate
course
illness.
Important
prospects
for
advancement
biomedical
research
therapy
are
by
biochip
technology
driven
intelligence.
This
includes
gene
chips,
organ-on-a-chip
systems,
biosensors.
However,
there
number
obstacles
must
overcome
before
can
effectively
theragnostics.
These
include
data
security,
privacy,
algorithmic
biases,
legal
frameworks,
acceptability.
vital,
order
realise
full
potential
AI-driven
address
these
constraints
means
extensive
validation,
diversified
datasets,
explainable
clear
communication.
anticipated
synergistic
combination
theragnostics
will
revolutionise
precision
continues
advance.
it
more
accurate
diagnoses,
achieve
tailored
therapeutics,
better
outcomes.
Language: Английский
Machine learning and clinical EEG data for multiple sclerosis: A systematic review
Artificial Intelligence in Medicine,
Journal Year:
2025,
Volume and Issue:
unknown, P. 103116 - 103116
Published: April 1, 2025
Language: Английский
A comprehensive review of neurotransmitter modulation via artificial intelligence: A new frontier in personalized neurobiochemistry
Jaleh Bagheri Hamzyan Olia,
No information about this author
Arasu Raman,
No information about this author
Chou‐Yi Hsu
No information about this author
et al.
Computers in Biology and Medicine,
Journal Year:
2025,
Volume and Issue:
189, P. 109984 - 109984
Published: March 14, 2025
Language: Английский
Software and hardware co-design of AI high-rate chips for parallel training of edge intelligence
Intelligent Decision Technologies,
Journal Year:
2024,
Volume and Issue:
18(4), P. 3259 - 3276
Published: Nov. 1, 2024
With
the
digital
transformation
of
information
technology
and
industry,
applicability
scenarios
edge
intelligent
terminals
are
expanding.
AI
chips
have
become
one
mainstream
core
devices
terminals.
How
to
select
suitable
according
application
through
systematic
analysis
has
an
urgent
problem
be
solved.
This
paper
first
provides
a
comparative
technical
architecture
advantages
disadvantages
chips;
then
proposes
low
implementation
complexity,
multi-code
rate
fusion
LDPC
parallel
coding
structure,
encoder
chip
design
scheme
using
this
structure
for
high-speed
transmission
applications.
Based
on
TSMC
130
nm
CMOS
standard
cell
library,
can
achieve
throughput
1.6
Gbps
at
200
MHz
clock
consume
only
184.3
m
W.
Compared
with
same
designed
in
conventional
architecture,
solution
reduce
storage
space
requirement
18.52%
architecture.
The
proposed
encoding
not
maintains
high
performance
but
also
significantly
reduces
demand
space,
making
it
good
choice
resource-constrained
environments.
Language: Английский