Effects of fermented corn cob on growth performance, digestive enzyme, immune response, and gene expression of Nile tilapia (Oreochromis niloticus) raised in biofloc system DOI

Hien Van Doan,

Supriya Wannavijit,

Khambou Tayyamath

et al.

Fish & Shellfish Immunology, Journal Year: 2025, Volume and Issue: unknown, P. 110413 - 110413

Published: May 1, 2025

Language: Английский

Antioxidant properties and bioactive compounds in rooibos (Aspalathus linearis) and tea (Camellia sinensis) infusions DOI
Julia Płatkiewicz,

Anna Łapawa,

Robert Frankowski

et al.

European Food Research and Technology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 31, 2025

Language: Английский

Citations

0
New insights into Notch signaling as a crucial pathway of pancreatic cancer stem cell behavior by chrysin-polylactic acid-based nanocomposite DOI Creative Commons
Eman M. Ragab,

Doaa M. El Gamal,

Fares F. Elnajjar

et al.

Discover Oncology, Journal Year: 2025, Volume and Issue: 16(1)

Published: Feb. 1, 2025

Pancreatic cancer is an extremely deadly illness for which there are few reliable treatments. Recent research indicates that malignant tumors highly variable and consist of a tiny subset unique cells, known as stem cells (CSCs), responsible the beginning spread tumors. These typically identified by expression specific cell surface markers. A population pancreatic with aberrantly active developmental signaling pathways has been in recent studies human Among these Notch pathway key regulator CSCs self-renewal, making it attractive target therapeutic intervention. Chrysin-loaded polylactic acid (PLA) polymeric nanoparticles systems have growing interest using platforms improved drug delivery. This review aims to explore innovative strategies targeted therapy optimized delivery manipulating leveraging PLA-based systems. Furthermore, we will assess capability PLA enhance bioavailability effectiveness gemcitabine cells. The insights gained from this potential contribute development novel treatment approaches combine advanced utilizing biodegradable nanoparticles.

Language: Английский

Citations

0
RNA signaling in medicinal plants: An overlooked mechanism for phytochemical regulation DOI
Esther Ugo Alum, Chidozie Dennis Udechukwu,

David Chukwu Obasi

et al.

Biochemistry and Biophysics Reports, Journal Year: 2025, Volume and Issue: 42, P. 102032 - 102032

Published: April 29, 2025

Language: Английский

Citations

0
Melphalan-Induced Ovarian Toxicity and Effects of Chrysin in an Experimental Rat Model: The Role Of Oxidative Stress and microRNA In Regulating Autophagy DOI
علی عبادی, Maryam Moghimian,

Seyd‐Hossein Abtahi‐Evari

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: May 5, 2025

Abstract This study aims to investigate the microRNA-modulatory effects of chrysin in mitigating melphalan-induced ovarian damage. Rats were divided into six groups: Group 1: Control; 2: Melphalan (1.5 mg/kg); 3: mg/kg) + Chrysin (50 4: (75 5: 6: mg/kg). was administered via injection, while given orally by gavage daily for two weeks. The results showed that toxicity impaired folliculogenesis and decreased expression miR-30a, miR-375, miR-204, leading increased autophagy cell death. High-dose treatment appeared counteract these modulating oxidative stress markers (MDA, SOD, GPX) restoring microRNA expression, thereby reducing death during folliculogenesis. These findings suggest high-dose may offer a potential therapeutic option protecting tissue from microRNAs Oxidative Stress.

Language: Английский

Citations

0
Effects of fermented corn cob on growth performance, digestive enzyme, immune response, and gene expression of Nile tilapia (Oreochromis niloticus) raised in biofloc system DOI

Hien Van Doan,

Supriya Wannavijit,

Khambou Tayyamath

et al.

Fish & Shellfish Immunology, Journal Year: 2025, Volume and Issue: unknown, P. 110413 - 110413

Published: May 1, 2025

Language: Английский

Citations

0