Review on biodegradable microsphere with special emphasis on inflammatory bowel disease & recent patents DOI Creative Commons

Supriya Shidhaye,

Krutika Nagpurkar,

Mayur B. Kale

et al.

Next Nanotechnology, Journal Year: 2025, Volume and Issue: 7, P. 100184 - 100184

Published: Jan. 1, 2025

Language: Английский

Advances in Lipid Nanoparticle‐Based Disease Treatment DOI Open Access
Yujie Zhou,

Qiqi Ge,

Xin Wang

et al.

ChemMedChem, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 17, 2025

Abstract Lipid nanoparticles (LNPs) have emerged as a transformative platform for the targeted delivery of therapeutic agents, revolutionizing treatment paradigms across spectrum diseases. Since inception liposomes in 1960s, lipid‐based nanotechnology has evolved to address limitations such poor bioavailability, off‐target effects, and instability, thereby enhancing efficacy safety drug administration. This review highlights latest advancements LNPs technology, focusing on their application cancer therapy, gene infectious disease management, glaucoma, other clinical areas. Recent studies underscore potential deliver messenger RNA (mRNA) small interfering (siRNA) precise genetic intervention, exemplified by breakthroughs interference CRISPR‐Cas9 genome editing. Additionally, been successfully employed ameliorate conditions, demonstrating versatility addressing both acute chronic disorders. However, challenges persist concerning large‐scale manufacturing, long‐term stability, comprehensive evaluations. Future research must focus optimizing formulations, exploring synergistic combinations with existing therapies, expanding scope treatable The integration into personalized medicine exploration applications diseases represent promising avenues further investigation. are poised play an increasingly central role development next‐generation therapeutics.

Language: Английский

Citations

1
RNA-based therapies for neurodegenerative disease: Targeting molecular mechanisms for disease modification DOI

Vishal Bhati,

Sonima Prasad,

Atul Kabra

et al.

Molecular and Cellular Neuroscience, Journal Year: 2025, Volume and Issue: unknown, P. 104010 - 104010

Published: May 1, 2025

Language: Английский

Citations

0
Nanostructured lipid carriers in cancer Therapy: Advances in passive and active targeting strategies DOI

Dana Alkhamach,

Saeed Ahmad Khan,

Khaled Greish

et al.

International Journal of Pharmaceutics, Journal Year: 2025, Volume and Issue: unknown, P. 125736 - 125736

Published: May 1, 2025

Language: Английский

Citations

0
Review on biodegradable microsphere with special emphasis on inflammatory bowel disease & recent patents DOI Creative Commons

Supriya Shidhaye,

Krutika Nagpurkar,

Mayur B. Kale

et al.

Next Nanotechnology, Journal Year: 2025, Volume and Issue: 7, P. 100184 - 100184

Published: Jan. 1, 2025

Language: Английский

Citations

0