Multiscale brain modeling: bridging microscopic and macroscopic brain dynamics for clinical and technological applications DOI Creative Commons
Ondřej Krejcar, Hamidreza Namazi

Frontiers in Cellular Neuroscience, Journal Year: 2025, Volume and Issue: 19

Published: Feb. 19, 2025

The brain's complex organization spans from molecular-level processes within neurons to large-scale networks, making it essential understand this multiscale structure uncover brain functions and address neurological disorders. Multiscale modeling has emerged as a transformative approach, integrating computational models, advanced imaging, big data bridge these levels of organization. This review explores the challenges opportunities in linking microscopic phenomena macroscopic functions, emphasizing methodologies driving progress field. It also highlights clinical potential including their role advancing artificial intelligence (AI) applications improving healthcare technologies. By examining current research proposing future directions for interdisciplinary collaboration, work demonstrates how can revolutionize both scientific understanding practice.

Language: Английский

Multiscale brain modeling: bridging microscopic and macroscopic brain dynamics for clinical and technological applications DOI Creative Commons
Ondřej Krejcar, Hamidreza Namazi

Frontiers in Cellular Neuroscience, Journal Year: 2025, Volume and Issue: 19

Published: Feb. 19, 2025

The brain's complex organization spans from molecular-level processes within neurons to large-scale networks, making it essential understand this multiscale structure uncover brain functions and address neurological disorders. Multiscale modeling has emerged as a transformative approach, integrating computational models, advanced imaging, big data bridge these levels of organization. This review explores the challenges opportunities in linking microscopic phenomena macroscopic functions, emphasizing methodologies driving progress field. It also highlights clinical potential including their role advancing artificial intelligence (AI) applications improving healthcare technologies. By examining current research proposing future directions for interdisciplinary collaboration, work demonstrates how can revolutionize both scientific understanding practice.

Language: Английский

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