Centering prayer in the treatment of bipolar disorder DOI Creative Commons

Yanín Machado,

Mauricio Chinchilla,

Robert Hesse

et al.

World Journal of Advanced Research and Reviews, Journal Year: 2024, Volume and Issue: 21(3), P. 2314 - 2323

Published: March 30, 2024

Bipolar Disorder (BD), formerly manic-depressive illness or manic depression, is a lifelong mood disorder and mental health condition that causes intense shifts in mood, energy levels, thinking patterns, behavior. These can last for hours, days, weeks, months, interrupting the ability to carry out daily tasks. The manageable with medications, talk therapy, lifestyle changes, other treatments, but therapy results are unreliable many patients. Most faith traditions have two forms of prayer: discursive contemplative. believers practice prayer. Medical research has shown statistical healing effects prayer, there considerably less on contemplative Hesse reports method teaching CP by asking volunteer help demonstrate analogy between human Divine relationships following quoted phases., Therefore, we hypothesize might produce significant depression improvement BP Two neurologists double-blind diagnosed five patients complaining BD normal subjects. All cases expressed their belief God, so not non-theistic meditation. Patients will be free medication selected during depressive episodes. Among trait markers frontal alpha asymmetry,55,56, changes qEEG cordance. A very stable QEEG pattern, consisting asymmetry, was observed all Hence, this pattern used compare before after CP. Our main result showed focal left Alpha increment disappeared Conclusion: promising tool treating organizing function interplay among brain networks subserve Cognition-emotion interactions prefrontal cortex.

Language: Английский

The Balance in the Head: How Developmental Factors Explain Relationships Between Brain Asymmetries and Mental Diseases DOI Creative Commons
Martina Manns, Georg Juckel, Nadja Freund

et al.

Brain Sciences, Journal Year: 2025, Volume and Issue: 15(2), P. 169 - 169

Published: Feb. 9, 2025

Cerebral lateralisation is a core organising principle of the brain that characterised by complex pattern hemispheric specialisations and interhemispheric interactions. In various mental disorders, functional and/or structural asymmetries are changed compared to healthy controls, these alterations may contribute primary symptoms cognitive impairments specific disorder. Since multiple genetic epigenetic factors influence both pathogenesis illness development asymmetries, it likely neural developmental pathways overlap or even causally intertwined, although timing, magnitude, direction interactions vary depending on However, underlying steps neuronal mechanisms still unclear. this review article, we briefly summarise what know about structural, functional, relationships outline hypothetical connections, which could be investigated in appropriate animal models. Altered cerebral features disorder, as trigger neuropathogenesis embedded asymmetrical organisation developing brain. Therefore, occurrence severity processing cognition probably cannot understood independently lateralised intra- networks. Conversely, impaired cellular processes can also hinder favourable asymmetry lead deficits particular.

Language: Английский

Citations

1
Accelerated intermittent theta burst stimulation for pharmacological treatment‐resistant bipolar depression: Protocol for double‐blind, randomized, sham‐controlled trial DOI Creative Commons
Taro Kishi, Kenji Sakuma,

Shun Hamanaka

et al.

Psychiatry and Clinical Neurosciences Reports, Journal Year: 2025, Volume and Issue: 4(1)

Published: Feb. 10, 2025

Abstract Background With 30%–50% of people with bipolar depression (BDep) not responding to multiple pharmacological treatments, alternative therapies are needed. Accelerated intermittent theta burst stimulation (aiTBS) over the left dorsolateral prefrontal cortex (L‐DLPFC) has been employed for individuals treatment‐resistant major depressive disorder (TR‐MDD). Imaging studies have revealed reduced regional activity L‐DLPFC both TR‐MDD and BDep (TR‐BDep), suggesting that aiTBS may be beneficial TR‐BDep. Methods A 6‐week, double‐blind, sham‐controlled, randomized trial will conducted compare efficacy safety in TR‐BDep (jRCTs042240019). Fifty iTBS sessions (1800 pulses/session) delivered 10 daily 5 consecutive days at 90% resting motor threshold. This protocol is termed as Fujita Neuromodulation Therapy Bipolar Depression (FNT‐BD). Twenty‐two participants (both sexes, aged 18–64 years) (DSM‐5‐TR, Type I) recruited. The response rate any given week follow‐up primary outcome, defined a reduction ≥50% Montgomery Åsberg Rating Scale (MADRS) score. Other outcomes include MADRS score changes, remission (10 ≥ score), Clinical Global Impression‐Improvement score, Impression‐Severity discontinuation rate, incidence individual adverse events. Results We anticipate who receive treatment show significant improvement depressing symptoms compared those receiving sham treatment. Conclusions study provide valuable evidence patients clinicians.

Language: Английский

Citations

0
Decoding depression: How DLPFC and SMA mediate stress perception's role in mental health? DOI
Xiaochen Cao, Yan Zhang, Huifen Wu

et al.

Journal of Affective Disorders, Journal Year: 2025, Volume and Issue: 379, P. 323 - 331

Published: March 12, 2025

Language: Английский

Citations

0
Tract-based structural and functional connectivity abnormalities in bipolar I disorder DOI Creative Commons

Liqian Cui,

Huixing Zeng,

Yixin Chen

et al.

Progress in Neuro-Psychopharmacology and Biological Psychiatry, Journal Year: 2025, Volume and Issue: unknown, P. 111297 - 111297

Published: Feb. 1, 2025

Language: Английский

Citations

0
A Unified Pathogenic Hypothesis for Mental Disorders Based on Schismogenesis DOI Creative Commons
Mauro García‐Toro, Rocío Gómez-Juanes

Biosystems, Journal Year: 2025, Volume and Issue: unknown, P. 105431 - 105431

Published: Feb. 1, 2025

Language: Английский

Citations

0
Epigenome Defines Aberrant Brain Laterality in Major Mental Illnesses DOI Creative Commons
Hamid M. Abdolmaleky, Shabnam Nohesara, Sam Thiagalingam

et al.

Brain Sciences, Journal Year: 2024, Volume and Issue: 14(3), P. 261 - 261

Published: March 7, 2024

Brain-hemisphere asymmetry/laterality is a well-conserved biological feature of normal brain development. Several lines evidence, confirmed by the meta-analysis different studies, support disruption laterality in mental illnesses such as schizophrenia (SCZ), bipolar disorder (BD), attention-deficit/hyperactivity (ADHD), obsessive compulsive (OCD), and autism. Furthermore, abnormal lateralization planum temporale (a critical structure auditory language processing) has been reported patients with SCZ, it considered major cause for onset verbal hallucinations. Interestingly, peripheral counterparts illness, particularly have also shown several structures human body. For instance, fingerprints SCZ exhibit aberrant asymmetry, while their hair whorl rotation random, 95% general population clockwise rotation. In this work, we present comprehensive literature review disturbances BD, ADHD, OCD, followed systematic epigenetic factors that may be involved health disorders. We will conclude discussion on whether existing non-pharmacological therapies rTMS ECT used to influence altered functional asymmetry right left hemispheres brain, along corresponding gene-expression patterns.

Language: Английский

Citations

2
Effect of γ-tACS on prefrontal hemodynamics in bipolar disorder: A functional near-infrared study DOI Creative Commons
Haiqi Wu, Qinghui Zhang, Li Wan

et al.

Journal of Psychiatric Research, Journal Year: 2024, Volume and Issue: 175, P. 227 - 234

Published: May 3, 2024

Transcranial alternating current stimulation (tACS) is a potential therapeutic psychiatric tool that has been shown to modulate clinical symptoms and brain function by inducing oscillations. However, direct evidence on the effects of gamma-tACS (γ-tACS) Bipolar I Disorder (BD-I) limited. In present study we used functional near-infrared spectroscopy explore prefrontal hemodynamic changes in BD-I patients receiving combined γ-tACS intervention addition pharmacological treatment.

Language: Английский

Citations

2
Behavioral lateralization in bipolar disorders: a systematic review DOI Creative Commons
Annakarina Mundorf,

Jette Borawski,

Sebastian Ocklenburg

et al.

International Journal of Bipolar Disorders, Journal Year: 2023, Volume and Issue: 11(1)

Published: Dec. 1, 2023

Abstract Background Bipolar disorder (BD) is often seen as a bridge between schizophrenia and depression in terms of symptomatology etiology. Interestingly, hemispheric asymmetries well behavioral lateralization are shifted towards tendency left-side or mixed-side bias whereas no shift observed subjects with depression. Given the role BD both, (hypo)manic depressive episodes, investigating an interesting objective. Method A systematic review studies including measures form handedness, footedness, eyedness, language was performed resulting 25 suitable studies. Results broad variety methods used to assess lateralization, especially for hindering integration results. Additionally, hand preference, frequently different cut-off scores classification systems. Overall, do not support alteration side preference subjects. Studies focusing on differences handedness demonstrate that show equal rates right- non-right-handedness general population. Few manic episodes point increased ear eye dominance, but small sample sizes conflicting results warrant further investigation. Conclusion The reinforce some disorders, such BD, should be treated homogenous group sub-groups analyzed within patient’s Particularly, clinical implications from neuroimaging highlight need study given they may important consider brain stimulation protocols.

Language: Английский

Citations

4
Transcranial Magnetic Stimulation DOI
Luigi Cattaneo

Neuromethods, Journal Year: 2024, Volume and Issue: unknown, P. 461 - 508

Published: Dec. 11, 2024

Citations

1
Centering prayer in the treatment of bipolar disorder DOI Creative Commons

Yanín Machado,

Mauricio Chinchilla,

Robert Hesse

et al.

World Journal of Advanced Research and Reviews, Journal Year: 2024, Volume and Issue: 21(3), P. 2314 - 2323

Published: March 30, 2024

Bipolar Disorder (BD), formerly manic-depressive illness or manic depression, is a lifelong mood disorder and mental health condition that causes intense shifts in mood, energy levels, thinking patterns, behavior. These can last for hours, days, weeks, months, interrupting the ability to carry out daily tasks. The manageable with medications, talk therapy, lifestyle changes, other treatments, but therapy results are unreliable many patients. Most faith traditions have two forms of prayer: discursive contemplative. believers practice prayer. Medical research has shown statistical healing effects prayer, there considerably less on contemplative Hesse reports method teaching CP by asking volunteer help demonstrate analogy between human Divine relationships following quoted phases., Therefore, we hypothesize might produce significant depression improvement BP Two neurologists double-blind diagnosed five patients complaining BD normal subjects. All cases expressed their belief God, so not non-theistic meditation. Patients will be free medication selected during depressive episodes. Among trait markers frontal alpha asymmetry,55,56, changes qEEG cordance. A very stable QEEG pattern, consisting asymmetry, was observed all Hence, this pattern used compare before after CP. Our main result showed focal left Alpha increment disappeared Conclusion: promising tool treating organizing function interplay among brain networks subserve Cognition-emotion interactions prefrontal cortex.

Language: Английский

Citations

0