Ultimately Sensitive Organic Bioelectronic Transistor Sensors by Materials and Device Structure Design

Advanced Functional Materials, Journal Year: 2019, Volume and Issue: 30(20)

Published: Sept. 4, 2019

Abstract Organic bioelectronic sensors are gaining momentum as they can combine high‐performance sensing level with flexible large‐area processable materials. This opens to potentially highly powerful systems for point‐of‐care health monitoring and diagnostics at low cost. Prominent detect biochemical recognition events, electrolyte‐gated organic field‐effect transistors (EGOFETs) electrochemical (OECTs) easily fabricated operated. EGOFETs recently shown be capable of label‐free single‐molecule detections, even in serum. progress report aims provide a critical perspective through selected overview the literature on both EGOFET OECT biosensors. Attention is paid correctly attribute them potentiometric amperometric biosensor categories, which important set right conditions quantification purposes. Moreover, deepen understanding mechanisms, support unpublished data, focus put two among most aspects, namely, capacitance interplay role Faradaic currents. The final aim rationale functional mechanisms encompassing sensors, improve materials devices' designs taking advantage processes that enhance response enabling extremely resulting ultimate sensitivity, selectivity, fast response.

Language: Английский

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Recent development in chitosan nanocomposites for surface‐based biosensor applications

Electrophoresis, Journal Year: 2019, Volume and Issue: 40(16-17), P. 2084 - 2097

Published: May 13, 2019

Abstract Recent years have witnessed ever expanding use of biosensors in the fields environmental monitoring, homeland security, pharmaceutical, food and bioprocessing, agricultural industries. To produce effective reliable biosensors, good quality immobilization biological recognition elements is critical. Chitosan its nanocomposites emerge as an excellent matrix on biosensor surface. As a natural polysaccharide, chitosan has many useful characteristics, such high permeability mechanical strength, biocompatibility non‐toxicity, availability, low cost. Due to presence amino hydroxyl groups chitosan, can easily crosslink with variety nanomaterials. This investigation nanocomposite‐based presents recent development innovations preparation coordination for various bio‐detection applications, including formed carbon nanomaterials, inorganic complexes. These nanocomposite based demonstrated sensitivity selectivity stability detection different types targets ranging from glucose, proteins, DNAs, small biomolecules bacteria. It our hope that this review will offer guidance novel open up opportunities field research.

Language: Английский

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Enzyme-modified electrodes for biosensors and biofuel cells

Materials Horizons, Journal Year: 2019, Volume and Issue: 6(7), P. 1336 - 1358

Published: Jan. 1, 2019

The use of protein engineering, designer polymers, and the introduction nanomaterials are key strategies for design next-generation bioelectrodes.

Language: Английский

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About the amplification factors in organic bioelectronic sensors

Materials Horizons, Journal Year: 2020, Volume and Issue: 7(4), P. 999 - 1013

Published: Jan. 1, 2020

A systematic comparison between electrochemical and organic bioelectronic sensors reveals a unified rational description for transistor amplified detection.

Language: Английский

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A review on nanomaterial-based field effect transistor technology for biomarker detection

Microchimica Acta, Journal Year: 2019, Volume and Issue: 186(11)

Published: Nov. 1, 2019

Language: Английский

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