Frontiers in Chemistry,
Journal Year:
2024,
Volume and Issue:
12
Published: May 13, 2024
In
droplet
microfluidics,
UV-Vis
absorption
spectroscopy
along
with
colorimetric
assays
have
been
widely
used
for
chemical
and
biochemical
analysis.
However,
the
sensitivity
of
measurement
can
be
limited
by
short
optical
pathlength.
Here
we
report
a
novel
design
to
enhance
removing
oil
converting
droplets
into
single-phase
aqueous
flow,
which
measured
within
U-shape
channel
long
The
flow
cells
were
fabricated
via
3D
printing.
calibration
results
demonstrated
complete
removal
effective
pathlengths
similar
designed
lengths
(from
5
20
mm).
cell
was
further
employed
in
microfluidic-based
phosphate
sensing
system.
levels
displayed
excellent
consistency
data
obtained
from
traditional
UV
This
overcomes
limitations
microfluidics
has
potential
situ
continuous
monitoring.
Analytical Chemistry,
Journal Year:
2023,
Volume and Issue:
95(27), P. 10422 - 10429
Published: June 29, 2023
Microfluidic
chips
are
in
critical
demand
for
emerging
applications
material
synthesis
and
biosensing.
Herein,
we
relied
on
ultrafast
laser-processing
technology
to
fabricate
a
three-dimensional
(3D)
microfluidic
chip,
which
semiconducting
polymer
nanoparticles
(SPNs)
were
continuously
synthesized
with
tunable
size
SPN-involved
online
fluorescence
sensing
was
implemented.
A
homogeneous
distribution
of
SPNs
can
be
readily
realized
due
the
efficient
mixing
powerful
vortices
3D
prevents
from
aggregating
throughout
process.
Moreover,
optimized
conditions,
unveiled
unique
an
ultrasmall
particle
(<3
nm)
good
monodispersity.
By
integrating
high-performance
further
developed
platform
ratiometric
assays
H2O2
oxidase-catalyzed
substrates
(e.g.,
glucose),
composite
neutral
red
(NR)
(SPNs/NR)
used
as
mediator.
The
limit
detection
(LOD)
is
0.48
μM,
LOD
glucose
3.33
μM
via
presented
platform.
This
synthesis-and-sensing
provides
new
avenue
facile
production
offers
exciting
prospects
field
biomarkers.
Micromachines,
Journal Year:
2023,
Volume and Issue:
14(9), P. 1722 - 1722
Published: Sept. 1, 2023
Particle
counting
serves
as
a
pivotal
constituent
in
diverse
analytical
domains,
encompassing
broad
spectrum
of
entities,
ranging
from
blood
cells
and
bacteria
to
viruses,
droplets,
bubbles,
wear
debris,
magnetic
beads.
Recent
epochs
have
witnessed
remarkable
progressions
microfluidic
chip
technology,
culminating
the
proliferation
maturation
chip-based
particle
methodologies.
This
paper
undertakes
taxonomical
elucidation
counters
based
on
physical
parameters
they
detect.
These
are
classified
into
three
categories:
optical-based
counters,
electrical-based
other
counters.
Within
each
category,
subcategories
established
consider
structural
differences.
Each
type
counter
is
described
not
only
terms
its
working
principle
but
also
methods
employed
enhance
sensitivity
throughput.
Additionally,
an
analysis
future
trends
related
provided.
Frontiers in Chemistry,
Journal Year:
2024,
Volume and Issue:
12
Published: May 13, 2024
In
droplet
microfluidics,
UV-Vis
absorption
spectroscopy
along
with
colorimetric
assays
have
been
widely
used
for
chemical
and
biochemical
analysis.
However,
the
sensitivity
of
measurement
can
be
limited
by
short
optical
pathlength.
Here
we
report
a
novel
design
to
enhance
removing
oil
converting
droplets
into
single-phase
aqueous
flow,
which
measured
within
U-shape
channel
long
The
flow
cells
were
fabricated
via
3D
printing.
calibration
results
demonstrated
complete
removal
effective
pathlengths
similar
designed
lengths
(from
5
20
mm).
cell
was
further
employed
in
microfluidic-based
phosphate
sensing
system.
levels
displayed
excellent
consistency
data
obtained
from
traditional
UV
This
overcomes
limitations
microfluidics
has
potential
situ
continuous
monitoring.
