A "signal-on" photoelectrochemical sensor based on hierarchical titanium dioxide nanowires/microflowers decorated graphite-like carbon nitride quantum dots for glutathione detection DOI

Romina Rezapour,

Majid Arvand, Maryam Habibi

et al.

Talanta, Journal Year: 2024, Volume and Issue: 285, P. 127448 - 127448

Published: Dec. 20, 2024

Language: Английский

Nanomaterials-driven paper-based biosensors for food contaminants detection: Classification, mechanism and applications DOI
Yang Song, Xiaoyun Xu, Hengyi Xu

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 532, P. 216512 - 216512

Published: Feb. 18, 2025

Language: Английский

Citations

5
High Selectivity Fluorescence and Electrochemical Dual-Mode Detection of Glutathione in the Serum of Parkinson’s Disease Model Mice and Humans DOI
Hui Dong, Weitian Chen, Ke Xu

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: 97(2), P. 1318 - 1328

Published: Jan. 9, 2025

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons and accumulation alpha-synuclein. Glutathione (GSH), key antioxidant, significantly depleted in PD patients. This study presents dual-mode detection strategy for selectively determining GSH using single probe. A series "turn-on" electrochemical fluorescent probes were developed, with resorufin (Re) serving as reporting unit featuring specific recognition sites. Among these, 7-(3,5-dinitrophenoxy)-3H-phenoxazin-3-one (Re-DNP) probe was selected its high selectivity both Its response to superior comparison that observed hydrogen sulfide (H2S) cysteine (Cys). For screen-printed carbon electrode (SPCE)/carbon nanotube (CNT) modified electrodes, limit 5 μM, linear range 25-500 μM. In fluorescence detection, produced 78-fold increase emission at 630 nm presence GSH, strong correlation between intensity concentration 10-700 2 When applied real clinical serum samples, demonstrated lower levels mice human patients compared healthy controls. method provides sensitive accurate tool potential applications understanding GSH's role related diseases.

Language: Английский

Citations

4
Nanozyme-Inhibited SERS Multichannel Paper-Based Sensor Array for the Quantification and Identification of Biothiols and Cancer Cells Based on Three Ag-Based Nanomaterials DOI
Linjie Wang, Yixin Chen,

Yang Ji

et al.

Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(28), P. 11353 - 11365

Published: July 6, 2024

Biothiols play essential roles in maintaining normal physiological functions, resisting oxidative stress, and protecting cell health. Establishing an effective reliable sensor array for the accurate quantification discrimination of diverse biothiols is extremely meaningful. In this work, Ag/Mn3O4, Ag3PO4, Ag3Cit with excellent oxidase-mimetic activity surface-enhanced Raman scattering (SERS)-enhanced features have been prepared loaded onto Whatman filter paper (WFP) to build SERS chips as three sensing channels, which can induce 3,3′,5,5′-tetramethylbenzidine (TMB) oxidation SERS-active reporters (TMBox) concurrently generate prominent signals. Nevertheless, addition suppress conversion from TMB TMBox, cause reduction signal TMBox. Interestingly, each channel different TMBox signals' variations due differences inhibition abilities exclusive properties chip, be plotted specific fingerprint patterns biothiol further translated into intuitive two-dimensional (2D) clustering profiles through linear discriminant analysis (LDA) hierarchical cluster (HCA) techniques precise identification these six minimum concentration 1 μM. More importantly, exploited intracellular glutathione (GSH), differentiate between cancer cells based on GSH contents even identify types tumor cells, demonstrating its powerful application prospects disease diagnosis.

Language: Английский

Citations

14
Multifunctional Eu-doped carbon dots nanoprobe for highly sensitive and selective determination of glutathione in biological fluid and cell imaging DOI
Haitham Saad Al-mashriqi,

Pascaline Sanga,

Jia Chen

et al.

Carbon, Journal Year: 2024, Volume and Issue: 228, P. 119380 - 119380

Published: June 22, 2024

Language: Английский

Citations

13
Portable dual-mode paper chips for highly sensitive and rapid determination of aflatoxin B1 via an aptamer-gated MOFs DOI
Shiqi Huang,

Xiao Song,

Shiyu Wang

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 457, P. 140182 - 140182

Published: June 21, 2024

Language: Английский

Citations

9
Fe3O4@ag@Pt nanoparticles with multienzyme like activity for total antioxidant capacity assay DOI
Li Tian,

Jiaoyuan Fang,

Xiaoli Wan

et al.

Food Chemistry, Journal Year: 2025, Volume and Issue: 473, P. 143064 - 143064

Published: Jan. 25, 2025

Language: Английский

Citations

1
A nanozyme multifunctional platform based on iron doped carbon dots derived from Tibetan Ganoderma lucidum waste for glucose sensing, anti-counterfeiting applications, and anticancer cell effect DOI
Linjie Wang,

Shujun Zheng,

Yan Liu

et al.

Talanta, Journal Year: 2024, Volume and Issue: 276, P. 126262 - 126262

Published: May 15, 2024

Language: Английский

Citations

7
Coupling of an Au@AgPt nanozyme array with an micrococcal nuclease-specific responsiveness strategy for colorimetric/SERS sensing of Staphylococcus aureus in patients with sepsis DOI Creative Commons
Xueqin Huang,

Yingqi Yang,

Hanlin Zhou

et al.

Journal of Pharmaceutical Analysis, Journal Year: 2024, Volume and Issue: 15(2), P. 101085 - 101085

Published: Aug. 27, 2024

Rapid and ultrasensitive detection of pathogen-associated biomarkers is vital for the early diagnosis therapy bacterial infections. Herein, we developed a close-packed ordered Au@AgPt array coupled with cascade triggering strategy surface-enhanced Raman scattering (SERS) colorimetric identification Staphylococcus aureus biomarker micrococcal nuclease (MNase) in serum samples. The trimetallic nanozymes can catalyze oxidation 3,3',5,5'-tetramethylbenzidine (TMB) molecules to SERS-enhanced oxidized TMB (oxTMB), accompanied by color change from colorless blue. In presence S. aureus, secreted MNase preferentially cut nucleobase AT-rich regions DNA sequences on magnetic beads (MBs) release alkaline phosphatase (ALP), which subsequently mediated oxTMB reduction inducing colorimetric/SERS signal fade away. Using this "on-to-off" strategy, target be recorded wide linear range limit 38 CFU/mL mode 6 SERS mode. Meanwhile, MNase-mediated characterized high specificity sensitivity successfully discriminated between patients sepsis (n = 7) healthy participants 3), as well monitored prognostic progression disease 2). Overall, benefiting highly active dense "hot spot" substrate, response dual-signal output, methodology will offer promising avenue infection.

Language: Английский

Citations

6
Highly electroactive thiazolium [5,4-d]thiazol-2,5-dicarboxylic acid-silver electrochemiluminescent metal–organic frameworks: synthesis, properties and application in glutathione detection DOI

Ru Yu,

Haoran Zhang, Ying Tu

et al.

Microchimica Acta, Journal Year: 2025, Volume and Issue: 192(2)

Published: Jan. 14, 2025

Language: Английский

Citations

0
Coordination-Driven Room-Temperature Phosphorescent Carbon Dot Nanozymes for Dual-Mode Glutathione Detection DOI

Meng-Xian Liu,

Xiao Zhang,

Wen-Ye Liu

et al.

Talanta, Journal Year: 2025, Volume and Issue: 290, P. 127833 - 127833

Published: Feb. 25, 2025

Language: Английский

Citations

0