Recent Progress in Biosensors for Depression Monitoring—Advancing Personalized Treatment DOI Creative Commons

Jiaju Yin,

Xinyuan Jia,

Haorong Li

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(9), P. 422 - 422

Published: Aug. 30, 2024

Depression is currently a major contributor to unnatural deaths and the healthcare burden globally, patient's battle with depression often long one. Because causes, symptoms, effects of medications are complex highly individualized, early identification personalized treatment key improving outcomes. The development wearable electronics, machine learning, other technologies in recent years has provided more possibilities for realization this goal. Conducting regular monitoring through biosensing technology allows comprehensive objective analysis than previous self-evaluations. This includes identifying depressive episodes, distinguishing somatization analyzing etiology, evaluating effectiveness programs. review summarizes research on depression. Special attention given that can be portable or wearable, potential enable patient use outside hospital, periods.

Language: Английский

Identification of mitophagy-related genes and analysis of immune infiltration in the astrocytes based on machine learning in the pathogenesis of major depressive disorder DOI
Lan Lei,

Cong-Ya Chen,

Yufei Wang

et al.

Journal of Affective Disorders, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

Citations

4
Mediation Effect of Resilience Between Social Support and Depression Symptoms in Patients With Strabismus: A Cross-Sectional Study DOI Creative Commons
Yawen Mo, Huiting Zhang, Xinping Yu

et al.

Journal of Multidisciplinary Healthcare, Journal Year: 2025, Volume and Issue: Volume 18, P. 459 - 468

Published: Jan. 1, 2025

The prevalence of depression symptoms in patients with strabismus is high. This study aimed to examine the relationship between social support, resilience, and how support mediated by resilience. A cross-sectional was conducted among adult undergoing surgery at an ophthalmic centre Guangzhou, China, March 2021 May 2023. Patients completed Self-Rating Depression Scale (SDS), Social Support Rating Scale, Connor-Davidson Resilience Scale. Multiple linear regression structural equation modeling explored symptoms. Of 200 patients, 28.5% had (21.5% mild, 6.0% moderate, 1.0% severe). mean SDS score (45.50 ± 11.60) significantly higher than healthy reference group (p < 0.001). (β=-0.407, P<0.001) resilience (β=-0.367, were predictors symptoms, which explained 44.2% all variations. partially accounting for 22.22% total effect (-1.543/-6.944). mediates strabismus. findings present highlight importance psychological improving depressive

Language: Английский

Citations

0
E2F2 induces microglial activation and augments depressive-like behavior in mice by repressing PTPN6 transcription DOI
Xin Jin, Yao Chen, Li Zhang

et al.

Cytotechnology, Journal Year: 2025, Volume and Issue: 77(2)

Published: Feb. 21, 2025

Language: Английский

Citations

0
Schaftoside Reduces Depression- and Anxiogenic-like Behaviors in Mice Depression Models DOI Creative Commons

Hu Yue,

Yaoxue Gan,

Lei Jia

et al.

Brain Sciences, Journal Year: 2025, Volume and Issue: 15(3), P. 238 - 238

Published: Feb. 24, 2025

Background: Major depressive disorder is a common mental health issue characterized by persistently low mood and high morbidity mortality. The major pathophysiology neuroinflammation, as evidenced elevated cytokine levels. Patients often fail to achieve full remission with the use of currently available antidepressants, prompting search for new treatment options. Schaftoside (SS), flavonoid found in traditional Chinese herbs, has both antioxidant anti-inflammatory properties. However, its antidepressant effects are poorly understood. Methods: Male C57BL/6 mice underwent chronic unpredictable mild stress (CUMS) lipopolysaccharide (LPS) induce depression- anxiety-like behaviors. SS was administered at 40, 80, 160 mg/kg 28 days. effect on depression-like behaviors assessed using behavioral assays, ELISA used measure pro-inflammatory cytokines serum hippocampus. Results: significantly decreased immobility forced swim tail suspension tests, increased sucrose preference test, reduced feeding latency novelty-suppressed test. These findings indicate improved depression showed that lowered interleukin-1 beta (IL-1β), IL-6, tumor necrosis factor-alpha levels hippocampus CUMS mice. Conclusions: Our study indicates anxiolytic effects, possibly through neuroinflammatory processes, making it promising therapeutic candidate depression, thus deserves further investigation into mechanisms clinical efficacy.

Language: Английский

Citations

0
Electrochemical Voltammetry Quantification of Dopamine based on Ceria-doped ZnAl2O4 DOI
Nandini Robin Nadar,

J. Deepak,

S.C. Sharma

et al.

Materials Chemistry and Physics, Journal Year: 2025, Volume and Issue: unknown, P. 130704 - 130704

Published: March 1, 2025

Language: Английский

Citations

0
Advances in Apolipoprotein-A4 Biosensing Assays for Depression Diagnosis DOI

Zahra Jamalizadeh Bahaabadi,

Sercan Karav, Amirhossein Sahebkar

et al.

Critical Reviews in Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 12

Published: April 29, 2025

Apolipoprotein-A4 (Apo-A4) is a plasma protein that plays role in various physiological and behavioral-emotional reactions when faced with stress. Studies have shown close relationship between Apo-A4 the onset of depression its symptoms. However, there currently no reliable laboratory approach to confirm diagnosis depression. Therefore, development precise effective technique assess might help early detection screening other related psychiatric diseases, as well tracking managing course treatment. As technology advances, biosensors become quick, accurate, sensitive tools for personal care illness diagnosis. Biosensors measuring detecting levels recently been designed. These studies emphasized accurate diagnostic measurement techniques. This review attempts give general overview introduce established measurement.

Language: Английский

Citations

0
The multifaceted roles of circular RNAs in cancer hallmarks: From mechanisms to clinical implications DOI Creative Commons

Indira Kundu,

Shivani Varshney,

Srikanth Karnati

et al.

Molecular Therapy — Nucleic Acids, Journal Year: 2024, Volume and Issue: 35(3), P. 102286 - 102286

Published: July 20, 2024

Language: Английский

Citations

3
Electrochemical biosensors for depression: Diagnosis and therapeutic monitoring DOI
Amir Asadi,

Felora Ferdosi,

Sanam Anoosheh

et al.

Clinica Chimica Acta, Journal Year: 2024, Volume and Issue: 567, P. 120091 - 120091

Published: Dec. 15, 2024

Language: Английский

Citations

2
Recent Progress in Biosensors for Depression Monitoring—Advancing Personalized Treatment DOI Creative Commons

Jiaju Yin,

Xinyuan Jia,

Haorong Li

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(9), P. 422 - 422

Published: Aug. 30, 2024

Depression is currently a major contributor to unnatural deaths and the healthcare burden globally, patient's battle with depression often long one. Because causes, symptoms, effects of medications are complex highly individualized, early identification personalized treatment key improving outcomes. The development wearable electronics, machine learning, other technologies in recent years has provided more possibilities for realization this goal. Conducting regular monitoring through biosensing technology allows comprehensive objective analysis than previous self-evaluations. This includes identifying depressive episodes, distinguishing somatization analyzing etiology, evaluating effectiveness programs. review summarizes research on depression. Special attention given that can be portable or wearable, potential enable patient use outside hospital, periods.

Language: Английский

Citations

1