International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 287, P. 138549 - 138549
Published: Dec. 9, 2024
Language: Английский
Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113172 - 113172
Published: Feb. 1, 2025
Language: Английский
Citations
1
Analytical Methods, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
The extensive use of antibiotics poses significant public health concerns, including the increase in drug-resistant bacteria and environmental pollution, underscoring urgent need for rapid, sensitive, specific antibiotic detection methods. Most current reviews on primarily focus categorizing based their types or classification sensors used, such as electrochemical, optical, colorimetric sensors. In contrast, this review proposes a novel systematic theoretical framework using seven popular molecular recognition elements-antibodies, aptamers, microorganisms, cells, peptides, molecularly imprinted polymers (MIPs), metal-organic frameworks (MOFs) direct modalities briefly discusses mechanism elements recognition. Additionally, it explores biosensors developed these elements, offering detailed analysis strengths limitations terms sensitivity, specificity, practicality. concludes by addressing challenges future directions, providing comprehensive perspective essential enhancing food safety protecting health.
Language: Английский
Citations
0
Food Chemistry, Journal Year: 2025, Volume and Issue: 480, P. 143890 - 143890
Published: March 15, 2025
Language: Английский
Citations
0
Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113664 - 113664
Published: April 1, 2025
Language: Английский
Citations
0
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2025, Volume and Issue: 340, P. 126332 - 126332
Published: May 9, 2025
Language: Английский
Citations
0
Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: May 15, 2025
Herein, an efficient luminol-H2O2 electrochemiluminescence (ECL) system with bimetallic organic gels as ECL signal booster and innovative heterosequence aptamer recognition a target conversion strategy is used to construct sensitive specific aptasensor for the detection of β2-microglobulin (B2M), key biomarker end-stage renal disease (ESRD). Impressively, porous Fe@Cu (Fe@Cu MOGs) act coreaction accelerators confinement-enhanced reactors system, amplifying by 21-fold compared traditional which greatly enhanced sensitivity biosensor. Compared homosequence approach competitive binding aptamers single site, synergistic multiple sites could improve specificity aptasensor, validated experiments molecular docking simulations. Therefore, developed exhibits remarkable dynamic range 10 fg/mL-1 μg/mL ultralow limit 0.9 fg/mL, superior previously reported works. Additionally, demonstrated consistent performance conventional clinical immunoturbidimetric assays high B2M concentration in 14 samples, well exhibiting trace levels that are undetectable immunoturbidimetry. This offers accurate platform recognition, promising applications detection, diagnosis, therapeutic monitoring, advancing scientific research on early pathological changes discovery.
Language: Английский
Citations
0
Talanta, Journal Year: 2024, Volume and Issue: 284, P. 127196 - 127196
Published: Nov. 13, 2024
Language: Английский
Citations
2
Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 19, 2024
Abstract Organic photoelectrochemical transistors (OPECT) have emerged as leading candidates for biosensing technologies, attributed to their high transconductance, zero operating voltage, and excellent biocompatibility. However, the practical application of OPECT in complex biological fluids is usually hindered by challenges such gate structures, undesired contamination, side reactions. Herein, a contamination‐free biosensor proposed based on nanochannel membrane‐isolated design, effectively preventing matrix from detection cell. Using adenosine triphosphate (ATP), biomarker malignant tumors Alzheimer's disease proof‐of‐principle, metal−organic framework (MOF)‐guarded entrance switch‐on strong chelation interaction between ATP Zn(II) nodes MOFs, which allowed sodium thiophosphate substrate pass through. Benefiting confinement effect nanochannels frameworks, encapsulated alkaline phosphatase molecules exhibited catalytic efficiency H 2 S production subsequent CdS electrode, thus altering transistor response. The device, combined with nanochannels‐regulated on‐off strategy not only prevented contamination biomatrix but also enabled rapid direct 1.0 n m within 15 min, providing an alternative insight into design device interference‐free matrices.
Language: Английский
Citations
2
Bioelectrochemistry, Journal Year: 2024, Volume and Issue: 161, P. 108843 - 108843
Published: Oct. 28, 2024
Language: Английский
Citations
1
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 287, P. 138549 - 138549
Published: Dec. 9, 2024
Language: Английский
Citations
0