A sensitive electrochemiluminescence immunosensor for CEA detection based on the ECL-RET between zinc-based metal–organic frameworks and ZiF-8@PDA DOI
Yige Li, Yingying Cheng,

Haoyi Ren

et al.

Bioelectrochemistry, Journal Year: 2024, Volume and Issue: 161, P. 108843 - 108843

Published: Oct. 28, 2024

Language: Английский

Using Signal Off-to-On Strategy for Designing Precise and Ultrasensitive Biosensor Towards Tumor Through Protein Variant Detection Based on Biocompatible Bimetallic Mof DOI
Zhihui Dai, Wenwen Tu, Huan Liu

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Using signal off-to-on strategy for designing precise and ultrasensitive biosensor towards hepatocellular carcinoma through protein variant detection based on biocompatible bimetallic MOF DOI
Wenwen Tu, Huan Liu, Junfei Wang

et al.

Biosensors and Bioelectronics, Journal Year: 2025, Volume and Issue: unknown, P. 117429 - 117429

Published: March 1, 2025

Language: Английский

Citations

0
Liquid Biopsy on Microfluidics: From Existing Endogenous to Emerging Exogenous Biomarkers Analysis DOI

Xiaowen Ou,

Peng Chen, Bi‐Feng Liu

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 18, 2025

Liquid biopsy is an appealing approach for early diagnosis and assessment of treatment efficacy in cancer. Typically, liquid involves the detection endogenous biomarkers, including circulating tumor cells (CTCs), extracellular vesicles (EVs), DNA (ctDNA), RNA (ctRNA), proteins. The levels these biomarkers are higher cancer patients compared to those healthy individuals. However, clinical application using biomarker analysis faces challenges due its low abundance poor stability circulation. Recently, a promising strategy involving engineering exogenous probes has been developed overcome limitations. These activated within microenvironment, generating distinct markers that can be easily distinguished from background biological signals. Alternatively, labeled with intrinsic vivo detected vitro after metabolic processes. In this review, we primarily focus on microfluidic-based techniques allow transition analyzing existing emerging ones. First, introduce common as well synthetic Next, discuss recent advancements both biomarkers. Lastly, provide insights into future directions microfluidic systems.

Language: Английский

Citations

0
Rapid and portable detection of hepatocellular carcinoma marker alpha-fetoprotein using a droplet evaporation-based biosensor DOI

Ying Ping Jia,

Hui Zhao,

Shichu Huang

et al.

Talanta, Journal Year: 2025, Volume and Issue: 294, P. 128189 - 128189

Published: April 18, 2025

Language: Английский

Citations

0
Sulfatase-Mediated Peroxidase-like Activity: A Chemiluminescence-Based Platform for High-Throughput Screening of Natural Inhibitors in Cancer Therapy DOI
Mengyuan Cui, Wenqing Li, Li Liu

et al.

Biosensors and Bioelectronics, Journal Year: 2025, Volume and Issue: unknown, P. 117562 - 117562

Published: May 1, 2025

Language: Английский

Citations

0
A sensitive electrochemiluminescence immunosensor for CEA detection based on the ECL-RET between zinc-based metal–organic frameworks and ZiF-8@PDA DOI
Yige Li, Yingying Cheng,

Haoyi Ren

et al.

Bioelectrochemistry, Journal Year: 2024, Volume and Issue: 161, P. 108843 - 108843

Published: Oct. 28, 2024

Language: Английский

Citations

1