
Chemosensors, Journal Year: 2025, Volume and Issue: 13(5), P. 164 - 164
Published: May 5, 2025
Photoelectrochemical (PEC) sensors have emerged as potential analysis techniques in recent years due to PEC’s benefits, which include straightforward operation, quick response times, and basic equipment. In this work, a new PEC sandwich immunoassay was fabricated, based on low-toxicity BiOI/BiOCl composites accompanied by enhanced signal detection via AgI-conjugated antibodies (Ab2-AgI). Specifically, the inorganic semiconductor were first utilized bioanalysis. Owing unique configuration of energy levels between BiOI BiOCl, photoelectric more excellent than those or BiOCl alone. Moreover, Ab2-AgI conjugates amplification components through specific antibody–antigen immunoreaction. presence target Ag, immobilized clearly improve steric hindrance sensing electrode effectively hinder transfer photo-induced holes; meanwhile, AgI NPs can competitively absorb excitation light. A immunosensing platform for detecting tumor markers at 0 V under visible light developed, using carcinoembryonic antigen (CEA) model analyte demonstrated an ultra-low limit 4.9 fg·mL−1. Meanwhile, it specificity stability, potentially opening up novel promising other critical biomarkers.
Language: Английский