The Journal of Physical Chemistry B,
Journal Year:
2024,
Volume and Issue:
128(41), P. 10258 - 10271
Published: Sept. 24, 2024
Polyaniline
(PANI)-based
molecularly
imprinted
polymers
were
investigated
for
their
efficacy
in
sensing
phenylalanine
(Phe)
when
fabricated
on
both
glassy
carbon
electrode
(GCE)
and
indium
tin
oxide
(ITO)
sheets.
This
study
highlights
the
superior
performance
of
PANI-MIP/ITO
over
PANI-MIP/GCE
Phe,
with
clear
distinct
redox
responses.
Molecular
computation
helps
to
understand
interaction
mechanism
between
PANI
where
molecular
crowding,
aggregated
clusters,
hydrogen
bonding,
π-π
stacking
facilitate
stable
interactions.
We
tested
specificity
Phe
by
PANI-MIP
different
amino
acids
such
as
cysteine,
tryptophan,
tyrosine
well
organic
molecules
ascorbic
acid,
allantoin,
sucrose,
urea,
confirming
its
remarkable
electrochemical
efficiency.
The
oxidation
response
curve
yielded
a
limit
detection
4.88
μM
quantification
16.3
μM,
comparable
or
better
than
earlier
reported
sensors.
work
demonstrates
promise
MIP-based
sensing.
It
also
lays
groundwork
future
investigations
into
optimizing
PANI-MIPs
nanocomposites
develop
more
selective
International Journal of Molecular Sciences,
Journal Year:
2025,
Volume and Issue:
26(5), P. 2317 - 2317
Published: March 5, 2025
Preserving
ovarian
function
is
important
to
women's
reproductive
health.
It
necessary
for
fertility
and
maintaining
the
overall
hormonal
balance.
Platelet-rich
plasma
(PRP)
an
autologous
containing
a
predominately
platelet
concentrate
prepared
from
fresh
blood.
has
been
observed
that
PRP
injections
into
ovary
can
renew
functional
cells
of
cortical
layer
follicles
reactivate
production
sex
hormones.
may
improve
woman's
in
case
premature
failure,
condition
after
chemotherapy
treatment,
or
during
climacteric
period.
The
main
markers
evaluate
procedure's
success
are
elevated
anti-Müllerin
hormone
enlarged
count
level
atrial
ovaries.
aim
this
review
identify
procedure
point
out
electrochemical
sensor
techniques.
Literature
was
selected
depending
on
including
excluding
criteria;
studies
were
sorted
by
topics
two
blocks:
biomarkers
electrochemistry.
As
acts
as
regenerative
care,
biosensors
provide
accurate,
real-time
data
biological
response
therapy.
biosensors'
ability
monitor
levels
follicle
development
serves
objective
effectiveness
restoring
function.
Together,
these
approaches
enable
more
precise
evaluation
health
outcomes
intervention.
