Harnessing Nanomaterials For Enhanced DNA‐Based Biosensing And Therapeutic Performance DOI Open Access

Xumin Pan,

Xiaoman Zhao,

Yanhong Lu

et al.

ChemBioChem, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 10, 2024

The integration of nanomaterials with DNA-based systems has emerged as a transformative approach in biosensing and therapeutic applications. Unique features DNA, like its programmability specificity, complement the diverse functions nanomaterials, leading to creation advanced for detecting biomarkers delivering treatments. Here, we review developments DNA-nanomaterial conjugates, emphasizing their enhanced functionalities potential across various biomedical We first discuss methodologies synthesizing these distinguishing between covalent non-covalent interactions. then categorize DNA-nanomaterials conjugates based on properties DNA involved, respectively. probes are classified by application into or uses, and, several highlighted recent progress living biological. Finally, current challenges future prospects this field, anticipating that significant will greatly enhance precision medicine.

Language: Английский

Nano biosensors: Classification, electrochemistry, nanostructures, and optical properties DOI Creative Commons
Ahmed Mahdi Rheima, Zainab T. Al‐Sharify, Ameen Alwan Mohaimeed

et al.

Results in Engineering, Journal Year: 2024, Volume and Issue: unknown, P. 103428 - 103428

Published: Nov. 1, 2024

Language: Английский

Citations

5
Dual-mode DNA nano-stage biosensing platform for efficient detection of uracil-DNA glycosylase activity in cells DOI

Dandan Hu,

Yanhong Ye,

Qianlin Zhu

et al.

Bioelectrochemistry, Journal Year: 2025, Volume and Issue: 165, P. 108950 - 108950

Published: Feb. 26, 2025

Language: Английский

Citations

0
Exploring Framework Nucleic Acids: A Perspective on Their Cellular Applications DOI Creative Commons
Zhaoyang Wang, Xin Wang,

Yao He

et al.

JACS Au, Journal Year: 2024, Volume and Issue: 4(11), P. 4110 - 4128

Published: Oct. 22, 2024

Cells are fundamental units of life. The coordination cellular functions and behaviors relies on a cascade molecular networks. Technologies that enable exploration manipulation specific events in living cells with high spatiotemporal precision would be critical for pathological study, disease diagnosis, treatment. Framework nucleic acids (FNAs) represent novel class acid materials characterized by their monodisperse rigid nanostructure. Leveraging exceptional programmability, convenient modification property, predictable atomic-level architecture, FNAs have attracted significant attention diverse applications such as cell recognition, imaging, manipulation, therapeutic interventions. In this perspective, we will discuss the utilization systems while critically assessing opportunities challenges presented burgeoning field.

Language: Английский

Citations

1
Harnessing Nanomaterials For Enhanced DNA‐Based Biosensing And Therapeutic Performance DOI Open Access

Xumin Pan,

Xiaoman Zhao,

Yanhong Lu

et al.

ChemBioChem, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 10, 2024

The integration of nanomaterials with DNA-based systems has emerged as a transformative approach in biosensing and therapeutic applications. Unique features DNA, like its programmability specificity, complement the diverse functions nanomaterials, leading to creation advanced for detecting biomarkers delivering treatments. Here, we review developments DNA-nanomaterial conjugates, emphasizing their enhanced functionalities potential across various biomedical We first discuss methodologies synthesizing these distinguishing between covalent non-covalent interactions. then categorize DNA-nanomaterials conjugates based on properties DNA involved, respectively. probes are classified by application into or uses, and, several highlighted recent progress living biological. Finally, current challenges future prospects this field, anticipating that significant will greatly enhance precision medicine.

Language: Английский

Citations

0