Medicina,
Journal Year:
2024,
Volume and Issue:
60(5), P. 735 - 735
Published: April 28, 2024
Training
and
expertise
in
regional
anaesthesia
have
increased
significantly
tandem
with
interest
over
the
past
two
decades.
This
review
outlines
most
recent
advances
focuses
on
novel
areas
of
including
fascial
plane
blocks.
Pharmacological
form
prolongation
drug
duration
liposomal
bupivacaine
are
considered.
Neuromodulation
context
is
outlined
as
a
potential
future
direction.
The
growing
use
outside
theatre
environment
current
thinking
managing
rebound
after
block
regression
also
discussed.
Recent
relevant
evidence
summarised,
unanswered
questions
outlined,
priorities
for
ongoing
investigation
suggested.
British Journal of Anaesthesia,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Spread
of
local
anaesthetic
solution
in
the
paravertebral
space
after
erector
spinae
plane
block
(ESPB)
is
variable.
We
evaluated
whether
spread
affected
by
patient
position
ESPB.
randomised
84
patients
to
receive
ESPB
at
T
Local
anaesthetic-contrast
mix
reached
space,
intercostal
and
neural
foramina
96.5%,
94.2%,
77.9%
individuals,
respectively.
Epidural
occurred
20
cases.
Prone
positioning
consistently
allowed
all
patients,
with
more
thoracic
level
compared
supine
(5.0
[1.9]
vs
3.1
[1.7],
difference
[95%
confidence
interval,
CI]:
1.9
[0.8-3.0]
levels,
P<0.001
for
spread;
2.8
1.4
[1.4],
CI]
levels:
[0.4-2.5],
P=0.004
4.3
[1.3]
3.2
[1.5],
1.0
[0.1-1.9],
P=0.019
spread).
extended
further
prone
than
lateral
group
(4.3
2.6
[1.5]
1.7
[0.8-2.6],
P<0.001).
Sensory
ventral
dermatomes
was
variable
participants.
significantly
enhanced
foramina,
suggesting
that
gravity
plays
a
substantial
role
spread.
Clinical
Trials.gov
(NCT06142630).
Saudi Medical Journal,
Journal Year:
2023,
Volume and Issue:
44(10), P. 1037 - 1046
Published: Sept. 30, 2023
To
measure
tramadol
intake
in
the
first
24
hours
post-surgery.
In
addition,
pain
scores
and
quality
of
recovery
were
evaluated
as
secondary
outcomes.A
total
80
adult
patients
scheduled
for
laparoscopic
cholecystectomy
randomized
into
2
groups
(with
without
external
oblique
intercostal
plane
block
[EOIPB]).
Control
group
received
standard
multimodal
analgesia,
EOIPB
was
applied
on
each
side
to
addition
analgesia.
The
primary
outcome
evaluate
consumption
at
postoperative
hours.
Secondary
outcomes
evaluating
Numeric
Rating
Scale
(NRS)
scores,
Quality
Recovery
score
(QoR-15),
sedation
score,
incidence
nausea
vomiting,
antiemetic
consumption.In
group,
median
(Q1,
Q3)
values
(0
[0,50]
mg)
found
be
significantly
lower
than
control
(50
[50,100]
(median
difference
-50)
(p<0.001).
NRS
during
rest
motion
compared
all
measurement
points
within
(p<0.05).
QoR-15
higher
No
differences
detected
other
parameters.External
resulted
less
consumption.
However,
there
no
minimal
clinically
important
about
opioid
On
hand,
analgesia
improved
overall
hours.Clinical
Trial
Reg.
No.:
NCT05536557.
Biology,
Journal Year:
2023,
Volume and Issue:
12(8), P. 1073 - 1073
Published: Aug. 1, 2023
Chronic
pain
is
a
common,
pervasive,
and
often
disabling
medical
condition
that
affects
millions
of
people
worldwide.
According
to
the
Global
Burden
Disease
survey,
painful
chronic
conditions
are
causing
largest
numbers
years
lived
with
disability
In
America,
more
than
one
in
five
adults
experiences
pain.
Erector
spinae
plane
block
novel
regional
anesthesia
technique
used
provide
analgesia
multiple
possible
uses
relatively
low
learning
curve
complication
rate.
Here,
we
review
erector
rationale,
mechanism
action
complications,
discuss
its
potential
use
for
future
directions
research
Journal of Pain Research,
Journal Year:
2024,
Volume and Issue:
Volume 17, P. 3047 - 3062
Published: Sept. 1, 2024
Now,
the
erector
spinae
plane
block
(ESPB)
is
widely
used
in
various
thoracolumbar
surgeries.
It
has
unique
advantages:
simple
and
convenient
operation,
low
safety
risks,
reduced
opioid
use.
The
ESPB
thoracic
surgery,
abdominal
spinal
surgery.
There
are
also
relevant
research
reports
on
postoperative
analgesia
during
general
anesthesia
This
article
searches
PubMed
Web
of
Science
databases
to
find
screen
studies
since
2019
retrospectively
summarizes
current
indications
ESPB.
methodological
quality
included
was
assessed
using
Cochrane
bias
risk
tool.
results
showed
that
generally
provides
low-level
clinical
evidence.
complex
anatomy
muscles
both
responsible
for
its
advantages
restricts
development.
Few
anatomical
have
clearly
completely
demonstrated
diffusion
relationship
local
anesthetics
among
structures
muscles.
uncontrollability
prevents
from
being
applied
a
wider
scale
with
high
level
To
further
clarify
scope
application
achieve
best
analgesic
effect,
future,
we
should
focus
course
distribution
their
fascia
nerves.
necessary
combine
anatomical,
imaging,
histological
methods
obtain
high-quality
evidence
guide
application.
BMJ Open,
Journal Year:
2025,
Volume and Issue:
15(1), P. e086392 - e086392
Published: Jan. 1, 2025
Introduction
Minimally
invasive
cardiac
surgery
(MICS)
is
important
for
enhanced
recovery
in
surgery.
However,
the
incidence
of
chronic
postsurgical
pain
(CPSP)
high
and
associated
with
worsened
quality
life,
as
well
raised
short-term
or
long-term
mortality.
The
mechanism
not
clear,
there
still
a
lack
safe
effective
preventive
measures.
Methods
analysis
Paravertebral
Adjunctive
Dexamethasone
Palmitate
Reducing
After
(PANDORA)
trial
parallel-group,
double-blinded,
randomised
controlled,
single-centre
study
recruiting
902
participants
undergoing
MICS.
Participants
will
be
1:1
ratio
to
dexamethasone
palmitate
(D-PAL)
emulsion
group
(DSP)
group.
To
investigate
effect
single
bolus
perineural
administration
D-PAL
an
adjuvant
treatment
standard
thoracic
paravertebral
block
(TPVB)
ropivacaine
decreases
CPSP
adult
patients
compared
DSP
combined
TPVB.
primary
endpoint
postoperative
at
3
months
following
defined
per
updated
International
Classification
Diseases.
new
development
increase
intensity
surgical
area
projected
onto
innervation
nerve
this
after
procedure
that
persists
least
months.
nature
evaluated
Brief
Pain
Inventory
Short
Form
(BPI-SF)
questionnaire.
Ethics
dissemination
was
approved
by
Committee
Xijing
Hospital,
First
Affiliated
Hospital
Air
Force
Military
Medical
University
(KY20232194-C-1).
Results
submitted
publication
peer-reviewed
journals
presented
academic
meetings.
Trial
registration
number
ClinicalTrials.gov,
NCT05920967
.