Pregnancy and COVID-19: Comparing ICU Outcomes for Pregnant and Nonpregnant Women DOI Creative Commons
Małgorzata Lipińska-Gediga, Waldemar Gożdzik, Jakub Śmiechowicz

et al.

Viruses, Journal Year: 2024, Volume and Issue: 17(1), P. 51 - 51

Published: Dec. 31, 2024

Background: This study compares organ dysfunction, treatment strategies, and unfavorable outcome rates between pregnant nonpregnant women admitted to the ICU with severe COVID-19, highlighting increased susceptibility of respiratory infections due physiological changes. Methods: A retrospective, age-matched was conducted at a referral center specializing in critical care for women. Data from 14 pregnant/postpartum 11 were analyzed admission on days 3, 5, 7. Results: Acute distress syndrome diagnosed 100% group 64% (p = 0.026). Inflammatory parameters similar groups, except lower ferritin levels compared (120 vs. 568 µg/L 90 616 day 3). Creatinine, lactate, lactate dehydrogenase significantly group. reduction SOFA score observed over time (from 7.0 4.0 points, p 0.009), while no change noticed 3.0 2.5 0.181). Unfavorable similar, two patients each succumbing disease 0.604). Conclusions: The findings suggest that pregnancy does not increase risk outcomes among COVID-19 receiving treatment. However, additional studies larger sample sizes are needed validate these observations.

Language: Английский

Extra-Corporeal Membrane Oxygenation in Pregnancy DOI Open Access

Tatsiana Romenskaya,

Yaroslava Longhitano, Aman Mahajan

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(6), P. 1634 - 1634

Published: March 13, 2024

Extracorporeal membrane oxygenation (ECMO) is a cardiac or pulmonary function support system that used in cases of refractory organ failure addition to conventional treatment. Currently, Level I evidence not yet available, which reflects improved outcomes with ECMO pregnant women, the use pregnancy should be indicated selected and only specialized centers. We searched articles most important scientific databases from 2009 until 31 December 2023 consulting also site ClinicalTrials.com find out about studies have been recently conducted are currently ongoing. matched combination following keywords: “ECMO pregnancy”, “H1N1 “COVID-19 “ARDS AND (cardiac arrest)”. number for each keyword combination: pregnancy” (665 articles); influenza H1N1” (384 “pregnancy (1006 ARDS” (2930 ARDS (24 “[ECMO arrest)]” (74 articles). After careful inspection, 43 papers fitted our scope. There two types ECMO: venous-venous (VV-ECMO) venous-arterial (VA-ECMO). The first-one necessary cope severe hypoxia: oxygen-depleted blood taken venous circulation, oxygenated, carbon dioxide removed extracorporeal circuit returned same system. VA-ECMO type mechanical assistance circulatory allows put failing at rest by ensuring adequate systemic de-oxygenation, avoiding multi-organ failure. main indications women cardiogenic shock, acute respiratory distress syndrome (ARDS), embolism, eclampsia. fetal ECMO, they distress, hypoxic-ischemic encephalopathy (HIE), twin-to-twin transfusion (TTTS). Until now, based on numerous clinical conducted, has shown successful therapeutic strategy where medical treatment unsuccessful. In well-selected patients, it appears safe associated low risk maternal complications. aim this review report properties (VV VA) its women.

Language: Английский

Citations

4
Acute management of massive pulmonary embolism in pregnancy DOI Creative Commons

Shahin Qadri,

Ashwini Bilagi,

Abha Sinha

et al.

Frontiers in Global Women s Health, Journal Year: 2025, Volume and Issue: 5

Published: Jan. 6, 2025

•Massive pulmonary embolism (PE) during pregnancy or the postpartum period is a rare but potentially lethal event.•Physiological changes in coagulation system and puerperium would lead to hypercoagulable state.•Diagnosis of PE remains challenge due physiological pregnancy. There are no validated scoring systems for assessing pregnant/postpartum women with suspected PE. Massive should be all cases haemodynamic instability pregnancy.•The Management massive timely aggressive. Thrombolysis has shown associated high maternal fetal survival (94% 88%). But other therapeutic options such as (catheter [or surgical] thrombectomy, ECMO) considered period, given risk major bleeding thrombolysis.•Thrombolysis most-used reasonably successful modality treatment avoided it can cause life-threatening haemorrhage. During post-partum thrombectomy choice. •To understand pathophysiology PE.•To appreciate their pros cons.•To need further work this area especially creating algorithm diagnosing period.

Language: Английский

Citations

0
Extracorporeal Membrane Oxygenation in Pregnant and Postpartum Women With Critical Coronavirus Disease 2019 (COVID-19) Acute Respiratory Distress Syndrome DOI

Amir A. Shamshirsaz,

John J. Byrne, Patrick S. Ramsey

et al.

Obstetrics and Gynecology, Journal Year: 2023, Volume and Issue: unknown

Published: Nov. 9, 2023

OBJECTIVE: To estimate the maternal survival and live-birth rates in pregnant women with acute respiratory distress syndrome (ARDS) secondary to critical coronavirus disease 2019 (COVID-19) who are treated extracorporeal membrane oxygenation (ECMO) by performing a systematic review meta-analysis. DATA SOURCES: From database inception through August 2023, we explored MEDLINE, Web of Science, EMBASE, CINAHL, ClinicalTrials.gov, Cochrane Central Register Controlled Trials. Studies reporting COVID-19 undergoing ECMO were included. METHODS OF STUDY SELECTION: Two reviewers separately ascertained studies, obtained data, evaluated study quality. Summary estimates measured, 95% CIs calculated. TABULATION, INTEGRATION, AND RESULTS: Nine retrospective case series 12 cohort studies identified 386 underwent ECMO. that from January 2020 October 2022. Four United States; three Turkey; two France; Israel; one each was Columbia, Germany, Italy, Kuwait, Poland, Republic Srpska, Arab Emirates, Kingdom, consortium Belgium, France, Switzerland, an international registry. The pooled rate among patients initiated on 75.6% (95% CI, 66.0–84.1%, I 2 =72%). 83.7% 76.8-89.6%, 153 neonates, =11%). When examined separately, results similar. CONCLUSION: Among attributable managed ECMO, high. SYSTEMATIC REVIEW REGISTRATION: PROSPERO, CRD42023442800.

Language: Английский

Citations

3
Use of Extracorporeal Membrane Oxygenation for Patients with Coronavirus Disease 2019 Infection DOI
Jessica M. Ruck, Errol L. Bush

Advances in Surgery, Journal Year: 2024, Volume and Issue: 58(1), P. 249 - 273

Published: June 29, 2024

Language: Английский

Citations

0
Pregnancy and COVID-19: Comparing ICU Outcomes for Pregnant and Nonpregnant Women DOI Creative Commons
Małgorzata Lipińska-Gediga, Waldemar Gożdzik, Jakub Śmiechowicz

et al.

Viruses, Journal Year: 2024, Volume and Issue: 17(1), P. 51 - 51

Published: Dec. 31, 2024

Background: This study compares organ dysfunction, treatment strategies, and unfavorable outcome rates between pregnant nonpregnant women admitted to the ICU with severe COVID-19, highlighting increased susceptibility of respiratory infections due physiological changes. Methods: A retrospective, age-matched was conducted at a referral center specializing in critical care for women. Data from 14 pregnant/postpartum 11 were analyzed admission on days 3, 5, 7. Results: Acute distress syndrome diagnosed 100% group 64% (p = 0.026). Inflammatory parameters similar groups, except lower ferritin levels compared (120 vs. 568 µg/L 90 616 day 3). Creatinine, lactate, lactate dehydrogenase significantly group. reduction SOFA score observed over time (from 7.0 4.0 points, p 0.009), while no change noticed 3.0 2.5 0.181). Unfavorable similar, two patients each succumbing disease 0.604). Conclusions: The findings suggest that pregnancy does not increase risk outcomes among COVID-19 receiving treatment. However, additional studies larger sample sizes are needed validate these observations.

Language: Английский

Citations

0