Sex differences in sleep apnea and Alzheimer’s Disease: role of cerebrovascular dysfunction

npj Women s Health, Journal Year: 2025, Volume and Issue: 3(1)

Published: May 5, 2025

Obstructive sleep apnea (OSA) significantly impacts cardiovascular health in post-menopausal females. Given that and cerebrovascular diseases are tightly linked, OSA-mediated on function Alzheimer's Disease (AD) risk also likely more manifest This review will: summarize sex differences function, the vascular hypothesis of AD, characterize OSA phenotype implications for control, highlight AD risk.

Language: Английский

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The intersection of delirium and long-term cognition in older adults: the critical role of delirium prevention

Journal of Neurology, Journal Year: 2025, Volume and Issue: 272(6)

Published: May 6, 2025

Language: Английский

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Comparison of Optic Nerve Sheath Diameter Measurements in Coronary Artery Bypass Grafting Surgery with Pulsatile and Non-Pulsatile Flow

Medicina, Journal Year: 2025, Volume and Issue: 61(5), P. 870 - 870

Published: May 9, 2025

Background and Objectives: In coronary artery bypass grafting (CABG) surgeries, monitoring intracranial pressure (ICP) is crucial due to neurological risks. Although pulsatile flow (PF) during cardiopulmonary (CPB) considered more physiological than non-pulsatile (NPF), its impact on ICP remains unclear. This study aimed compare preoperative postoperative optic nerve sheath diameter (ONSD) measurements between PF NPF techniques evaluate their effect changes. Materials Methods: Sixty patients undergoing elective CABG (aged 45–75 years, ASA II-III-IV) were enrolled divided into two groups depending the technique determined by surgeon: (Group P, n = 30) NP, 30). ONSD performed with ultrasound before surgery (Tpreop) after (Tpostop). Hemodynamic parameters jugular carotid vessel diameters also recorded. Statistical analysis included t-tests, Mann–Whitney U-tests, chi-square tests, Pearson correlation. Results: Both demonstrated significant increases in postoperatively compared values (p < 0.001). However, no statistically difference magnitude of change was observed > 0.05). Group P showed lower ejection fractions higher total inotrope requirements NP 0.01), but these factors did not translate differences dynamics. Conclusions: increased significantly surgery, regardless perfusion type. strategies comparable terms effects as reflected ultrasonography appears be a simple, rapid, non-invasive tool for perioperative cardiac surgery. Further studies are needed confirm findings dynamic intraoperative neurocognitive assessments.

Language: Английский

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Evaluation of the effect of fluid management on intracranial pressure in patients undergoing laparoscopic gynaecological surgery based on the ratio of the optic nerve sheath diameter to the eyeball transverse diameter as measured by ultrasound: a randomised controlled trial

BMC Anesthesiology, Journal Year: 2024, Volume and Issue: 24(1)

Published: Sept. 7, 2024

Language: Английский

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The hidden cost of hypotension: redefining hemodynamic management to improve patient outcomes

Brazilian Journal of Anesthesiology (English Edition), Journal Year: 2024, Volume and Issue: 75(1), P. 844581 - 844581

Published: Dec. 5, 2024

Language: Английский

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Association between intraoperative blood pressure and postoperative delirium in cardiac surgery: A question yet to be resolved

Journal of Clinical Anesthesia, Journal Year: 2024, Volume and Issue: 101, P. 111717 - 111717

Published: Dec. 12, 2024

Language: Английский

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