British Journal of Oral and Maxillofacial Surgery, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 1, 2024
Language: Английский
British Journal of Oral and Maxillofacial Surgery, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 1, 2025
Language: Английский
Citations
0
British Journal of Oral and Maxillofacial Surgery, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 1, 2025
Language: Английский
Citations
0
Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(5), P. 1404 - 1404
Published: Feb. 20, 2025
Background/Objectives: Tendinopathy is the preferred term to describe various tendon pathologies, including paratendinitis, tendinitis, and tendinosis, in absence of histopathological evidence biopsy specimens. The management tendinopathies challenging; rest, physiotherapy (such as eccentric training), injections, shock waves, orthotics, medical therapy, surgery are main therapeutic options offered patient. conservative treatment still difficult, but several have been proposed, use anti-inflammatory molecules. In this retrospective study, we aimed assess efficacy a approach improving pain functional improvement hip bursitis (HB) biceps tendinitis (BT) patients. Methods: A series data concerning application Polynucleotides High Purification Technology (PN HPTTM) 47 patients with BT HB was analyzed. All received three bi-weekly injections PN HPTTM (T0–T2). Follow-up visits were performed at T3 (8 weeks from T2) T4 (24 T2). Both visual analog scale (VAS) for assessment impairment (FI) scores processed form anonymized clinical evaluations. Results: Statistically significant differences (p < 0.001) reduction (−85%) (+86%) found end treatment. levels patient satisfaction (PS) Clinical Global Improvement—Impression (CGI-I) equal 93% 98%, respectively. According analyses, other (e.g., gender, age, BMI) did not appear influence positive outcomes. Conclusions: shown improve both deterioration tendonitis similar manner treatments. These analyses may open up new avenues implementation approaches tendinitis.
Language: Английский
Citations
0
Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(9), P. 3043 - 3043
Published: April 28, 2025
Background/Objectives: Natural-origin PN HPT™ (Polynucleotides High Purification Technology) protect and revitalize chondrocytes, synoviocytes, cartilage with a regenerative medicine perspective following intra-articular injection. This six-month, open-label data collection aimed to validate the benefits documented in previous studies of single injection proprietary HPT™/HA-based medical device improving both subjective objective manifestations knee osteoarthritis real-life ambulatory patients genders unilateral or bilateral osteoarthritis. Methods: Efficacy safety assessments, conducted at baseline before HPT™/HA after three six months follow-up, included Lequesne index patient-assessed Numeric Pain Rating Scale (NPRS), which focuses on pain intensity, as primary endpoints. The Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) was secondary endpoint. Results: After months, mean score improved by 43.8% 51.4%, respectively. Concurrently, NPRS improvements were 42.2% 54.7%. Furthermore, 32% investigators 15.5% treated deemed optimal clinical outcomes no worsening. Conclusions: With some limitations due uncontrolled design relying rating scales only, study confirms all findings about combining HA same for
Language: Английский
Citations
0
British Journal of Oral and Maxillofacial Surgery, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 1, 2024
Language: Английский
Citations
0
British Journal of Oral and Maxillofacial Surgery, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 1, 2024
Language: Английский
Citations
0