Finite element analysis of anatomically-modelled prosthetic incus for ossicular chain reconstruction DOI Creative Commons
Masoud Mohseni-Dargah, Christopher J. Pastras, Payal Mukherjee

et al.

Computers in Biology and Medicine, Journal Year: 2025, Volume and Issue: 187, P. 109770 - 109770

Published: Feb. 4, 2025

Ossicular chain reconstruction (OCR) is the gold standard for repairing conductive hearing loss (CHL) using prosthetic devices. However, few techniques can validate prosthesis performance before translational implementation. This study not only validates a Finite Element (FE) model examining (reconstructed) middle ear biomechanics, but also evaluates potential of personalised devices OCR. Additionally, this research examines tricalcium phosphate (TCP), as biomaterial, besides titanium and hydroxyapatite (HA), commonly used biomaterials use in (personalised) Here, designed FE tested hypothesis that 3D anatomically modelled (prosthetic incus) reliably restore sound transmission appropriate biomaterials, including titanium, HA, or TCP. Our modelling examined biomechanics after replacement each biomaterial assignment. Results demonstrated agreement with experimental vibrometry recordings ossicular motion earlier numerical simulations. incus closely mimicked normal revealing its analysis revealed no significant differences between TCP prostheses functions, serving first-order evidence their support establishes FE-based framework OCR following imaging, which valuable future treatments patients CHL due to dysfunction. simulations evaluate function prostheses, helping surgeon make well-informed decisions regarding outcomes.

Language: Английский

Finite element analysis of anatomically-modelled prosthetic incus for ossicular chain reconstruction DOI Creative Commons
Masoud Mohseni-Dargah, Christopher J. Pastras, Payal Mukherjee

et al.

Computers in Biology and Medicine, Journal Year: 2025, Volume and Issue: 187, P. 109770 - 109770

Published: Feb. 4, 2025

Ossicular chain reconstruction (OCR) is the gold standard for repairing conductive hearing loss (CHL) using prosthetic devices. However, few techniques can validate prosthesis performance before translational implementation. This study not only validates a Finite Element (FE) model examining (reconstructed) middle ear biomechanics, but also evaluates potential of personalised devices OCR. Additionally, this research examines tricalcium phosphate (TCP), as biomaterial, besides titanium and hydroxyapatite (HA), commonly used biomaterials use in (personalised) Here, designed FE tested hypothesis that 3D anatomically modelled (prosthetic incus) reliably restore sound transmission appropriate biomaterials, including titanium, HA, or TCP. Our modelling examined biomechanics after replacement each biomaterial assignment. Results demonstrated agreement with experimental vibrometry recordings ossicular motion earlier numerical simulations. incus closely mimicked normal revealing its analysis revealed no significant differences between TCP prostheses functions, serving first-order evidence their support establishes FE-based framework OCR following imaging, which valuable future treatments patients CHL due to dysfunction. simulations evaluate function prostheses, helping surgeon make well-informed decisions regarding outcomes.

Language: Английский

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