Differential association between childhood trauma subtypes and neurocognitive performance in adults with major depression DOI Creative Commons
Min Wang,

Jinxue Wei,

Yikai Dou

et al.

BMC Psychiatry, Journal Year: 2024, Volume and Issue: 24(1)

Published: Nov. 6, 2024

Neurocognitive impairment is one of the prominent manifestations major depressive disorder (MDD). Childhood trauma enhances vulnerability to developing MDD and contributes neurocognitive dysfunctions. However, distinct impacts different types childhood on processes in remain unclear. This study comprised 186 individuals diagnosed with 268 healthy controls. was evaluated using 28-item Trauma Questionnaire-Short Form. abilities, encompassing sustained attention, vigilance, visual memory, executive functioning, were measured by Cambridge Neuropsychological Testing Automated Battery. Multivariable linear regressions revealed that diagnosis independently associated impairment. Physical neglect impaired memory working memory. planning. Interactive analysis physical/sexual abuse a high level vigilance emotional linked better performance cognitive flexibility patients. Furthermore, abuse, physical be risk factors for early-onset, chronic episodes. Thus, specific associations between various traumas development depression are complex phenomena need further study.

Language: Английский

Amygdala hyperactivity in PTSD: disentangling predisposing from consequential factors in a prospective longitudinal design DOI Creative Commons
Lycia D. de Voogd, Mahur M. Hashemi, Wei Zhang

et al.

Biological Psychiatry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

0
Childhood Trauma Exposure is Associated with Decreased Amygdala and Insula Functional Connectivity in Individuals with Alcohol Use Disorder DOI
Primavera A. Spagnolo,

Robin Chholak,

A. F. M. Jalal Ahamed

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Differential association between childhood trauma subtypes and neurocognitive performance in adults with major depression DOI Creative Commons
Min Wang,

Jinxue Wei,

Yikai Dou

et al.

BMC Psychiatry, Journal Year: 2024, Volume and Issue: 24(1)

Published: Nov. 6, 2024

Neurocognitive impairment is one of the prominent manifestations major depressive disorder (MDD). Childhood trauma enhances vulnerability to developing MDD and contributes neurocognitive dysfunctions. However, distinct impacts different types childhood on processes in remain unclear. This study comprised 186 individuals diagnosed with 268 healthy controls. was evaluated using 28-item Trauma Questionnaire-Short Form. abilities, encompassing sustained attention, vigilance, visual memory, executive functioning, were measured by Cambridge Neuropsychological Testing Automated Battery. Multivariable linear regressions revealed that diagnosis independently associated impairment. Physical neglect impaired memory working memory. planning. Interactive analysis physical/sexual abuse a high level vigilance emotional linked better performance cognitive flexibility patients. Furthermore, abuse, physical be risk factors for early-onset, chronic episodes. Thus, specific associations between various traumas development depression are complex phenomena need further study.

Language: Английский

Citations

1