
Molecular Psychiatry, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 26, 2024
Language: Английский
Molecular Psychiatry, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 26, 2024
Language: Английский
Nature Reviews Psychology, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 16, 2024
Language: Английский
Citations
15Neuron, Journal Year: 2024, Volume and Issue: 112(16), P. 2799 - 2813.e9
Published: July 15, 2024
Every day, hundreds of thousands people undergo general anesthesia. One hypothesis is that anesthesia disrupts dynamic stability-the ability the brain to balance excitability with need be stable and controllable. To test this hypothesis, we developed a method for quantifying changes in population-level stability complex systems: delayed linear analysis estimation (DeLASE). Propofol was used transition animals between awake state anesthetized unconsciousness. DeLASE applied macaque cortex local field potentials (LFPs). We found neural dynamics were more unstable unconsciousness compared state. Cortical trajectories mirrored predictions from destabilized systems. mimicked effect propofol simulated networks by increasing inhibitory tone. This turn networks, as observed data. Our results suggest dynamical required consciousness.
Language: Английский
Citations
7Psychiatry Research Communications, Journal Year: 2025, Volume and Issue: unknown, P. 100203 - 100203
Published: Jan. 1, 2025
Language: Английский
Citations
0Journal of Affective Disorders Reports, Journal Year: 2025, Volume and Issue: unknown, P. 100932 - 100932
Published: May 1, 2025
Language: Английский
Citations
0Trends in Neurosciences, Journal Year: 2024, Volume and Issue: 47(10), P. 766 - 776
Published: Sept. 10, 2024
Language: Английский
Citations
3Molecular Psychiatry, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 26, 2024
Language: Английский
Citations
0