Neurosurgery Clinics of North America, Journal Year: 2023, Volume and Issue: 35(1), P. 125 - 133
Published: Oct. 6, 2023
Language: Английский
Neurosurgery Clinics of North America, Journal Year: 2023, Volume and Issue: 35(1), P. 125 - 133
Published: Oct. 6, 2023
Language: Английский
Biomedical Signal Processing and Control, Journal Year: 2024, Volume and Issue: 102, P. 107369 - 107369
Published: Dec. 21, 2024
Language: Английский
Citations
0medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown
Published: Dec. 14, 2023
Patients with drug-resistant temporal lobe epilepsy often undergo intracranial EEG recording to capture multiple seizures in order lateralize the seizure onset zone. This process is associated morbidity and ends postoperative recurrence. Abundant interictal (between-seizure) data captured during this process, but these currently play a small role surgical planning. Our objective was predict laterality of zone using patients epilepsy. We performed retrospective cohort study (single-center for model development; two-center validation). studied undergoing at University Pennsylvania (internal cohort) Medical South Carolina (external between 2015 2022. developed logistic regression EEG. compared concordance model-predicted side surgery good poor outcomes. 47 (30 women; ages 20-69; 20 left-sided, 10 right-sided, 17 bilateral onsets) were analyzed development internal validation. 19 (10 23-73; 5 4 bilateral) external The cross-validated area under curve trained spike rates 0.83 predicting left-sided 0.68 right-sided onset. Balanced accuracies 79.3% 78.9% left- predictions, respectively. predicted higher outcome. In conclusion, signatures are distinct across lateralities. Left-sided onsets easier distinguish than onsets. A on accurately identifies zones predicts
Language: Английский
Citations
1Neurosurgery Clinics of North America, Journal Year: 2023, Volume and Issue: 35(1), P. 125 - 133
Published: Oct. 6, 2023
Language: Английский
Citations
0