Peptide Based Engineering of Extracellular Vesicles for Cancer Theranostics and Vaccine DOI
Abhimanyu Thakur

International Journal of Peptide Research and Therapeutics, Journal Year: 2024, Volume and Issue: 31(1)

Published: Dec. 18, 2024

Language: Английский

Management of hypertension addressing hyperuricaemia: introduction of nano-based approaches DOI Creative Commons
Koyeli Girigoswami,

Radhakrishnan Arunkumar,

Agnishwar Girigoswami

et al.

Annals of Medicine, Journal Year: 2024, Volume and Issue: 56(1)

Published: May 16, 2024

Uric acid (UA) levels in blood serum have been associated with hypertension, indicating a potential causal relationship between high UA and the progression of hypertension. Therefore, reduction level is considered strategy for lowering mitigating pressure. If an individual at risk developing or already manifesting elevated pressure, this intervention could be integral part comprehensive treatment plan. By addressing hyperuricaemia, practitioners may subsidize optimization pressure regulation, which illustrates importance as valuable within broader context hypertension management. In analysis, we outlined operational principles effective xanthine oxidase inhibitors hyperuricaemia along exploration contribution nanotechnology to field.

Language: Английский

Citations

1
iRGD-Guided Silica/Gold Nanoparticles for Efficient Tumor-Targeting and Enhancing Antitumor Efficacy Against Breast Cancer DOI Creative Commons

Xuefeng Hou,

Qi Chen, Ying Fang

et al.

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 19, P. 8237 - 8251

Published: Aug. 1, 2024

Breast cancer presents significant challenges due to the limited effectiveness of available treatments and high likelihood recurrence. iRGD possesses both RGD sequence C-terminal has dual functions targeting membrane penetration. iRGD-modified nanocarriers can enhance drug tumor vascular endothelial cells penetration new microvessels, increasing concentration in tissues.

Language: Английский

Citations

1
Engineering Docetaxel Micelles for Enhanced Cancer Therapy Through Intermolecular Forces DOI Creative Commons
Hao Wang, Feirong Gong, Jiajie Liu

et al.

Bioengineering, Journal Year: 2024, Volume and Issue: 11(11), P. 1078 - 1078

Published: Oct. 28, 2024

Docetaxel has exhibited excellent therapeutic effects in cancer treatment; however, its hydrophobicity, short blood circulation time, and high toxicity restrict clinical application. The use of mPEG-PLA micelles to deliver docetaxel into the body been verified as an effective approach enhance efficacy. However, are easily disassembled bloodstream, which can lead premature drug release. To broaden application scenarios mPEG PLA micelles, we utilized π–π stacking effect intermolecular force design a novel mPEG-PLA-Lys(Fmoc) micelle stability permeability drug-loaded micelles. result showed that for injection did not alter tissue selectivity docetaxel. Intravenous nude mice better antitumor efficacy than tumor recurrence rate is 0%, significantly lower (100%). designed by this research institute anticipated improve

Language: Английский

Citations

1
Silent threats of organophosphates: surging pollutants, harmful impacts, remediation strategies, and viable eco-friendly alternatives DOI

P. Durgadevi,

Koyeli Girigoswami, Karthick Harini

et al.

Toxicology and Environmental Health Sciences, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 3, 2024

Language: Английский

Citations

0
Peptide Based Engineering of Extracellular Vesicles for Cancer Theranostics and Vaccine DOI
Abhimanyu Thakur

International Journal of Peptide Research and Therapeutics, Journal Year: 2024, Volume and Issue: 31(1)

Published: Dec. 18, 2024

Language: Английский

Citations

0