Associations between neutrophil percentage-to-albumin ratio with all-cause and cause-specific mortality among US cancer survivors: evidence from NHANES 2005–2018

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: April 17, 2025

Background The neutrophil percentage-to-albumin ratio (NPAR) had been suggested as a potential prognostic biomarker in various health outcomes. However, its association with mortality cancer survivors remains unclear. Methods A total of 3,022 from the National Health and Nutrition Examination Survey (NHANES) 2005–2018 were linked to outcomes Death Index (NDI). Weighted Cox proportional hazards models was conducted investigate between NPAR all-cause, cardiovascular disease (CVD) hazard (HR) 95% confidence interval (CI) calculated. Restricted cubic spline (RCS) used clarify non-linear association. Additionally, analyses for stratification sensitivity performed. Results During median follow-up 75 months, 790 all-cause deaths occurred, including 244 209 CVD. After adjustment covariates, higher independently associated increased risk (HR = 1.09, CI 1.06–1.13), 1.05, 0.99–1.12), CVD 1.13, 1.06–1.21). RCS revealed U-shaped relationship mortality, thresholds 12.76 13.60, respectively. Below threshold, reduced 0.90, 0.82–0.99; HR 0.87, 0.76–0.99), whereas above significantly 1.14, 1.09–1.18; 1.15, 1.07–1.24). Subgroup confirmed these findings. Conclusion along linear underscores valuable marker survivors.

Language: Английский

Depression Is Associated with a Higher Risk of Mortality among Breast Cancer Survivors: Results from the National Health and Nutrition Examination Survey–National Death Index Linked Study

Brain Sciences, Journal Year: 2024, Volume and Issue: 14(7), P. 732 - 732

Published: July 21, 2024

Breast cancer (BC) and depression are globally prevalent problems. Numerous reviews have indicated the high prevalence of among BC survivors. However, long-term impact on survival survivors has not been well explored. For this investigation, we aimed to explore relationship between BC, depression, mortality from a national random sample adult American women. Data U.S. National Health Nutrition Examination Survey (years 2005–2010) were linked with data Death Index up December 31st, 2019. A total 4719 women (ages 45 years older) included in study 5.1% having breast more than tenth (12.7%) depression. The adjusted hazard ratio (HR) for all-cause risk those was 1.50 (95% CI = 1.05–2.13) compared without BC. In analysis, highest both (HR 3.04; 95% 1.15–8.05) or moderated by cardiovascular diseases, anemia, smoking, age, PIR, marital status. Our analysis provides vital information factors that could be helpful interventions reduce addition, given higher co-occurring collaborative healthcare practices should help widespread screening treatment

Language: Английский

Cognitive Functioning Influences Mortality Risk Among Older Adults with COPD

Healthcare, Journal Year: 2024, Volume and Issue: 12(22), P. 2220 - 2220

Published: Nov. 7, 2024

Background/Objeectives: Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of mortality in the United States (U.S.), with rates varying by disease severity, comorbidities, and sociodemographic factors. Cognitive impairment has been independently associated increased mortality, but not well studied relation to COPD despite being frequently overlooked comorbidity patients. The purpose this nationwide study was assess relationship between low cognitive performance risk among older adults while adjusting for major health-related characteristics.

Language: Английский