Ultrasound-assisted metabolite detection in different extraction processes of Bletilla striata and bitter metabolite detection

Ultrasonics Sonochemistry, Journal Year: 2025, Volume and Issue: 114, P. 107266 - 107266

Published: Feb. 10, 2025

Bletilla striata, a medicinal orchidaceous plant, is recognized for its significant pharmacological value. However, the lack of comparative metabolomic data across different extraction methods analyzing bioactive components has significantly undervalued application potential B. striata in traditional Chinese medicine market. Using six ultrasound-assisted and UPLC-MS/MS, this study identified 1,945 metabolites extracts. The dominant categories were lipids (51.35%), flavonoids (18.00%), phenolic acids (12.51%). KEGG analysis revealed alterations isoflavonoids biosynthesis pathways. Thirteen bitter metabolites, including cinnamic acid, tubers, underscoring their applications, such as anti-inflammatory, antioxidant antibacterial activities. Optimizing can better preserve extracts, thereby enhancing applications food pharmaceutical industries.

Language: Английский

Structural insights and biological activities of flavonoids: Implications for novel applications

Food Frontiers, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 16, 2024

Abstract Flavonoids are a major class of polyphenolic compounds that occur naturally in plants and widely distributed various dietary products. exhibit prominent physicochemical properties biological activities, thereby garnering considerable attention. Notably, the functionalities flavonoids structurally dependent. Variations chemical structure lead to differences characteristics among different flavonoid types. Structural alterations can modify these characteristics, influencing activities mechanisms action. However, structural variations their implication have not been comprehensively elucidated. In this review, we outline flavonoids, discuss biosynthesis, vivo digestion, absorption, particularly emphasize diverse action associated with structures. By summarizing current scientific findings, aim elucidate structure–activity relationships provide theoretical basis for development new applications, which will help target design functional molecules moieties food pharmaceutical industries use drug development. Practical Application : Understanding guide products supplements targeted health benefits. leveraging knowledge relationships, food, innovate formulations enhance bioavailability efficacy, potentially leading creation tailored specific conditions or needs. This research lays groundwork novel flavonoid‐based interventions aimed at promoting human well‐being.

Language: Английский

Apigenin as an emerging hepatoprotective agent: current status and future perspectives

Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15

Published: Dec. 19, 2024

Apigenin (C

Language: Английский