3D-Printed Hydrogel Scaffolds Loaded with Flavanone@ZIF-8 Nanoparticles for Promoting Bacteria-Infected Wound Healing DOI Creative Commons
Jian Yu, Xin Huang, Fang‐Ying Wu

et al.

Gels, Journal Year: 2024, Volume and Issue: 10(12), P. 835 - 835

Published: Dec. 18, 2024

Bacterial-infected skin wounds caused by trauma remain a significant challenge in modern medicine. Clinically, there is growing demand for wound dressings with exceptional antibacterial activity and robust regenerative properties. To address the need, this study proposes novel multifunctional dressing designed to combine efficient gas exchange, effective microbial barriers, precise drug delivery capabilities, thereby promoting cell proliferation accelerating healing. This work reports development of 3D-printed hydrogel scaffold incorporating flavanone (FLA)-loaded ZIF-8 nanoparticles (FLA@ZIF-8 NPs) within composite matrix κ-carrageenan (KC) konjac glucomannan (KGM). The forms stable dual-network structure through chelation KC potassium ions intermolecular hydrogen bonding between KGM. not only enhances mechanical stability but also improves its adaptability complex environments. In mildly acidic conditions, FLA@ZIF-8 NPs release Zn2+ controlled manner, providing sustained effects vivo studies using rat full-thickness infected model demonstrated that FLA@ZIF-8/KC@KGM significantly accelerated healing, showcasing superior performance treatment wounds.

Language: Английский

Metal-based antimicrobial agents in wound Dressings: Infection management and the challenge of antibiotic resistance DOI

Haihong Peng,

Derong Dong, Sizhou Feng

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160726 - 160726

Published: Feb. 1, 2025

Language: Английский

Citations

0
Experimental study of biocompatible polycaprolactone composite membranes blended with short oligomers of biosourced triarylmethane-based polyaryletherketone DOI

Huihui Qiao,

Naïma Ahmed Omar, Fanny Coumes

et al.

Sustainable materials and technologies, Journal Year: 2025, Volume and Issue: 43, P. e01323 - e01323

Published: March 1, 2025

Language: Английский

Citations

0
Designing of electrospun unidirectional water transport nanofiber membranes: mechanisms, structures, and applications DOI
Lei Li, Xinyue Yang, Weimin Kang

et al.

Polymer, Journal Year: 2025, Volume and Issue: unknown, P. 128221 - 128221

Published: March 1, 2025

Language: Английский

Citations

0
Cellulose-based bilayer films with asymmetric properties for the sealing of tissue lesions DOI Creative Commons
Ufuk Gürer, Salma Mansi, M. C. Reuter

et al.

Cellulose, Journal Year: 2025, Volume and Issue: unknown

Published: March 23, 2025

Language: Английский

Citations

0
Effect of Carbodiimide Crosslinking on Gelatin-Carboxymethylcellulose-Polycaprolactone Scaffold Properties for Wound Dressing Applications DOI Open Access

Manus Sriswat,

Fasai Wiwatwongwana

Engineering Technology & Applied Science Research, Journal Year: 2025, Volume and Issue: 15(2), P. 21450 - 21455

Published: April 3, 2025

This research investigated the feasibility of fabricating 3D porous scaffolds from gelatin, carboxymethylcellulose (CMC) and polycaprolactone (PCL) using freeze-drying technique for wound dressing applications. The were crosslinked Dehydrothermal Treatment (DHT) 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) combination with N-hydroxysuccinimide (NHS). Their morphological mechanical properties analyzed to determine optimal condition. For DHT crosslinking, results demonstrated that average pore size ranged 127.25 150.77 µm, which was smaller than in non-crosslinked scaffolds. porosity 64.84% to72.08%, decreasing as CMC content increased. gelatin scaffold 35% (w/w) 30% PCL exhibited best overall properties. It provided highest porosity, a compressive strength 47.39 MPa, higher scaffold. Under EDC/NHS conditions, 145.40 µm 184.80 70.24% 74.48%. These characteristics indicate larger compared Although its lower scaffold, it remained Therefore, can be implied is suitable use skin substitute applications

Language: Английский

Citations

0
Development of an aligned nanofiber composite silk fibroin multilayer dressings: Accelerating wound healing and reducing scar formation DOI
Jiahao Zhao, Yongchao Wang, Fei Lu

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 143178 - 143178

Published: April 1, 2025

Language: Английский

Citations

0
Hydrogel‐Based Smart Materials for Wound Healing and Sensing DOI Creative Commons
Thi Hoai Nhung Duong,

Thi Thuy Truong,

Thanh Van Phan

et al.

Aggregate, Journal Year: 2025, Volume and Issue: unknown

Published: April 22, 2025

ABSTRACT Recent advancements in hydrogel‐based flexible materials have revolutionized wound healing and monitoring strategies. These offer promising solutions for medical treatment real‐time diagnostics. Their rich water content, biocompatibility, tunable properties closely mimic the natural extracellular matrix, supporting regeneration. Unlike traditional materials, systems address critical issues such as material stability toxicity while integrating advanced devices. This review highlights latest innovations materials. It focuses on flexibility, potential integration with smart systems. The covers design principles fabrication techniques nanofibers, elastomers, conducting polymers. also discusses development of electronic skin innovative dressings. In addition, explains how sensing capabilities, stimuli‐responsive functions, antibacterial agents are incorporated into these Finally, article examines challenges future directions field. emphasizes transformative multifunctional improving continuous monitoring.

Language: Английский

Citations

0
Using polycaprolactone and sodium alginate to prepare self-pumping/super-absorbent/transportable drug dressings for stage 3–4 pressure ulcer treatment DOI

Dongxing Dong,

Zhiqiang Cheng,

Jingjing Zhang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 278, P. 134711 - 134711

Published: Aug. 14, 2024

Language: Английский

Citations

2
3D-Printed Hydrogel Scaffolds Loaded with Flavanone@ZIF-8 Nanoparticles for Promoting Bacteria-Infected Wound Healing DOI Creative Commons
Jian Yu, Xin Huang, Fang‐Ying Wu

et al.

Gels, Journal Year: 2024, Volume and Issue: 10(12), P. 835 - 835

Published: Dec. 18, 2024

Bacterial-infected skin wounds caused by trauma remain a significant challenge in modern medicine. Clinically, there is growing demand for wound dressings with exceptional antibacterial activity and robust regenerative properties. To address the need, this study proposes novel multifunctional dressing designed to combine efficient gas exchange, effective microbial barriers, precise drug delivery capabilities, thereby promoting cell proliferation accelerating healing. This work reports development of 3D-printed hydrogel scaffold incorporating flavanone (FLA)-loaded ZIF-8 nanoparticles (FLA@ZIF-8 NPs) within composite matrix κ-carrageenan (KC) konjac glucomannan (KGM). The forms stable dual-network structure through chelation KC potassium ions intermolecular hydrogen bonding between KGM. not only enhances mechanical stability but also improves its adaptability complex environments. In mildly acidic conditions, FLA@ZIF-8 NPs release Zn2+ controlled manner, providing sustained effects vivo studies using rat full-thickness infected model demonstrated that FLA@ZIF-8/KC@KGM significantly accelerated healing, showcasing superior performance treatment wounds.

Language: Английский

Citations

0