Carboxymethyl chitosan-gelatin based films filled with whey protein-stabilized nanoscale essential oils for skin wound healing: In vivo and in vitro studies

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141119 - 141119

Published: Feb. 1, 2025

Language: Английский

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Material Design, Fabrication Strategies, and the Development of Multifunctional Hydrogel Composites Dressings for Skin Wound Management

Biomacromolecules, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 17, 2025

The skin is fragile, making it very vulnerable to damage and injury. Untreated wounds can pose a serious threat human health. Three-dimensional polymer network hydrogels have broad application prospects in wound dressings due their unique properties structure. therapeutic effect of traditional limited, while multifunctional composite show greater potential. Multifunctional regulate moisture through formula adjustment. Moreover, be combined with bioactive ingredients improve performance healing applications. Stimulus-responsive respond specifically the environment meet needs different stages. This review summarizes material types, structure, properties, design considerations, formulation strategies for hydrogel used healing. We discuss various types recently developed dressings, highlights importance tailoring physicochemical addresses potential challenges preparing dressings.

Language: Английский

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4D printing polymeric biomaterials for adaptive tissue regeneration

Bioactive Materials, Journal Year: 2025, Volume and Issue: 48, P. 370 - 399

Published: Feb. 22, 2025

Language: Английский

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3D printed eutectogel dissolving microneedles patch loaded with chitosan-based nanoparticles for diabetic wound management

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 307, P. 142018 - 142018

Published: March 12, 2025

Language: Английский

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A Narrative Review of Bioactive Hydrogel Microspheres: Ingredients, Modifications, Fabrications, Biological Functions, and Applications

Small, Journal Year: 2025, Volume and Issue: unknown

Published: March 19, 2025

Abstract Hydrogel microspheres are important in regenerative medicine and tissue engineering, acting as cargos of cells, drugs, growth factors, bio‐inks for 3D printing, medical devices. The antimicrobial anti‐inflammatory characteristics hydrogel good treating injured tissues. However, the biological properties should be modified optimal treatment various body parts with different physiological biochemical environments. In addition, specific preparation methods required to produce customized shapes sizes clinical applications. Herein, advances biomedical applications reviewed. Synthesis precursor solutions, manufacturing methods, strategies enhancing functions these described. involvement bioactive repair is also discussed. This review anticipates fostering more insights into design, production, application biomedicine.

Language: Английский

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A remotely triggered phase change hydrogel dressing for controlled release and promoting healing of infected wounds

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 161828 - 161828

Published: March 1, 2025

Language: Английский

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A multifunctional metformin loaded carboxymethyl chitosan/tannic acid/manganese composite hydrogel with promising capabilities for age-related bone defect repair

Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: unknown, P. 123526 - 123526

Published: March 1, 2025

Language: Английский

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Core‐Shell Structure‐Based Smart Hydrogel Wound Dressing with Endogenous and Exogenous Dual Adhesion Dynamic Response to Promote Wound Healing

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: March 21, 2025

Abstract Herein, MIL‐88b‐NH 2 nanocage is designed with adenine inside the cage and tannins as gating outside cage. Based on this core‐shell structure, polyvinyl alcohol/carboxymethyl chitosan/MIL/adenine/tannic acid (PCMAT) hydrogels are able to respond endogenously exogenously at different stages of wound healing. The engineered hydrogel have tunable adhesion intelligence. optimal PCMAT‐0.3 reduced pore size ≈13.5 µm under endogenous response conditions, antimicrobial performance reached more than 80% within 6 h. Tensile strength strain break by 8.47% 60.52% respectively exogenous conditions. Evaluation healing effect mouse back tissue shows that rate significantly better control group without incorporation day 14. It provides an idea for development smart dressing integrates multifunctionality.

Language: Английский

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A hydrogel-based composite facilitates efficient and recyclable tetracycline biodegradation in aquatic environments

Environmental Research, Journal Year: 2025, Volume and Issue: unknown, P. 121524 - 121524

Published: April 1, 2025

Language: Английский

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Magnetron Sputtered Carboxymethyl Chitosan Nonwovens as Antibacterial and Exudate Management Dressings

Journal of Applied Polymer Science, Journal Year: 2025, Volume and Issue: unknown

Published: April 8, 2025

ABSTRACT Excessive exudate within the wound can readily result in fluid retention and bacterial infection. Carboxymethyl chitosan (CMCS) nonwoven effectively absorb excess exudate, providing a moist environment for healing. However, CMCS shows poor antimicrobial activity neutral or weakly alkaline environment, absorbent gel property of makes its wet antibacterial modification very difficult. Therefore, Zn‐coated dressings (Zn@CMCS) with management properties were prepared by template‐assisted magnetron sputtering. The Zn 5 @CMCS sputtering time min have excellent air permeability (> 6000 mm/s), high swelling degree (~2500%), superior transition properties. Moreover, exhibits significant against Staphylococcus aureus Escherichia coli . Additionally, benefiting from low coating area (~18%), cytocompatibility. This study provides insights into nonwet

Language: Английский

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