Characterization and anti-Vibrio activity of citral-chitosan Schiff base complexed tannic acid-zinc slow-release bacteriostatic formulations

LWT, Journal Year: 2025, Volume and Issue: unknown, P. 117780 - 117780

Published: April 1, 2025

Language: Английский

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Advancements and Prospects of pH-Responsive Hydrogels in Biomedicine

Gels, Journal Year: 2025, Volume and Issue: 11(4), P. 293 - 293

Published: April 15, 2025

As an intelligent polymer material, pH-sensitive hydrogels exhibit the capability to dynamically sense alterations in ambient pH levels and subsequently initiate corresponding physical or chemical responses, including swelling, contraction, degradation, ion exchange. Given significant variations inherent human pathophysiological microenvironments, particularly tumor tissues, inflammatory lesions, gastrointestinal system, these smart materials demonstrate remarkable application potential across diverse domains such as targeted drug delivery systems, regenerative medicine engineering, biosensing, disease diagnostics. Recent breakthroughs nanotechnology precision have substantially propelled advancements design of pH-responsive hydrogels. This review systematically elaborates on current research progress future challenges regarding biomedical applications, with particular emphasis their stimulus–response mechanisms, fabrication methodologies, multifunctional integration strategies, scenarios.

Language: Английский

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An Antifreezing Scaffold‐Based Cryopreservation Platform of Stem Cells for Convenient Application in Wound Repair

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 14(4)

Published: Dec. 26, 2024

Efficient cryopreservation of stem cells is crucial to fabricating off-the-shelf cell products for tissue engineering and regeneration medicine. However, it remains challenging due utilization toxic cryoprotectants reducing ice-related cryodamages during freeze-thaw cycle, stringent post-thaw washing process, further integration with scaffolds form constructs downstream applications. Herein, a novel platform based on an antifreezing polyvinylpyrrolidone/gellan gum/gelatin (PGG) scaffold together reported L-proline assisted pre-dehydration strategy. Results show that this capable inhibiting extra-/intracellular ice, thus can achieve high cryoprotection efficacy (≈95%) without using any eliminate traditional process. Meanwhile, the post-thawed maintain their proliferation, differentiation, paracrine functionalities. More importantly, biocompatibility three dimensional structure PGG scaffold, cell-laden be directly used as wound repair by mitigating inflammation promoting collagen deposition at regenerating sites. This present work demonstrates feasibility scaffold-based cells, which may advance clinical translation.

Language: Английский

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TA/PVP hydrogel coating enhanced photo-Fenton membranes with antifouling and self-cleaning properties for efficient oil–water emulsion separation

Separation and Purification Technology, Journal Year: 2024, Volume and Issue: unknown, P. 131252 - 131252

Published: Dec. 1, 2024

Language: Английский

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