Injectable Chitosan-Based Hydrogel for Photothermal Treatment of Drug-Resistant Bacterial Infections to Accelerate Wound Healing DOI

Desheng Cai,

Kairu Che,

Yuqin Yang

et al.

Published: Jan. 1, 2024

Language: Английский

Comprehensive Quality Evaluation and Botanical Differentiation of Typhae Pollen Using UHPLC‐DAD/Q‐TOF‐MS and Multivariate Chemometric Analysis DOI Open Access

Fang Tian,

Ying Zhang, Li-Xia Chen

et al.

Phytochemical Analysis, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 20, 2025

ABSTRACT Introduction In China, Typhae Pollen (TP) has been extensively utilized as a medicinal product, which is the dried pollen from male inflorescences of Typha angustifolia L. (TA), orientalis Presl (TO), or species within same genus. However, existing methods for differentiating botanical origin and controlling quality TP are confusing, unreliable, unsystematic. Objectives This study aims to elucidate microstructural similarities differences between grains two develop comprehensive method qualitative quantitative analysis multiple flavonoids phenolic acids in TP. Methodology Scanning electron microscopy (SEM) was employed examine grains. A analytical approach developed using ultra‐high performance liquid chromatography with diode array detection quadrupole‐time‐of‐flight mass spectrometry quantitatively qualitatively analyze 17 acids. Discrepancies constituents were further explored partial least squares discrimination hierarchical clustering analysis. Results Microscopic examination revealed distinct species, could be distinguished SEM. The established these constituents—comprising 13 4 acids—proved reliable accurate. flavonoid glycosides categorized into three groups. TA, average contents 1, 2, 3, 4, 8, 12 higher than TO, whereas reverse true 7, 14, 16, 17. Constituents 9, 10, unique TO. And constituent 14 should chosen more appropriate indicator Chemometric techniques effectively differentiated TA Conclusions contributes enhancing control facilitating identification provides an experimental foundation improving its standards.

Language: Английский

Citations

1
Advances in the study of polysaccharide-based hydrogel wound dressings DOI
Yu Zhang, Ning Qiao, Lihua Liu

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142134 - 142134

Published: March 1, 2025

Language: Английский

Citations

1
Conjugated Polymer Composite Flexible Wood Hydrogel-Mediated Sequential Nir-Ii Photothermal and Photodynamic Anti-Bacteria and Macrophage Polarization for Acute Sinusitis​ DOI

Lei He,

Yongze Liu, Xiaofeng Ma

et al.

Published: Jan. 1, 2025

Bacterial infection-induced acute sinusitis​​is prevalent and easy to convert into chronic sinusitis that is difficult heal with the increased environmental pollution bacterial drug resistance nowadays. For nasal cavity, flexibility hydrogels (LM@P/S@CP@Hemin) involve flexible wood-modified logs, photo-active conjugated polymers, immunomodulator (Hemin), immobilization hydrogel were prepared address this challenge. Hemin has a strong regulatory effect on macrophages perform anti-inflammation cellular ROS clearance abilities. The logs provide mechanical strength support. In vitro experiments verified could generate photothermal of 48 °C under near-infrared-II laser irradiation in deep bone tissues produce reactive oxygen species (ROS) initiate photodynamic effect. Based these properties, induced an anti-bacterial 98.5% inhibition rate against methicillin-resistant Staphylococcus aureus. Meanwhile, exhibited excellent ability excessive promotion anti-inflammatory M2 macrophage generation avoid uncontrolled inflammation. vivo rabbit model histological analysis further confirmed great therapeutic LM@P/S@CP@Hemin for based therapy. Therefore, material can adapt environment treat sinusitis​​.

Language: Английский

Citations

0
Effect of rutin on the structural and functional properties of ovalbumin DOI Creative Commons

Qian Cui,

Yanqiu Ma, Xue Ping Mao

et al.

Poultry Science, Journal Year: 2025, Volume and Issue: 104(2), P. 104816 - 104816

Published: Jan. 16, 2025

Language: Английский

Citations

0
Fabrication of amino-capped Pluronic F127 with aldehyde dextran chains: A strategy improving extensibility, compressibility and self-healing hydrogel for wound healing DOI

Yutao Zheng,

Pengqi Guo,

Fengyuan Yong

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 304, P. 140774 - 140774

Published: Feb. 10, 2025

Language: Английский

Citations

0
Protein-polysaccharide based nanogel/hydrogel composite with controlled continuous delivery of drug for enhanced wound healing DOI
Yi Mao, Bing Tian Zhao,

Linghui Xu

et al.

Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: unknown, P. 123407 - 123407

Published: Feb. 1, 2025

Language: Английский

Citations

0
Injectable Arctium lappa polysaccharide-based composite hydrogel enhances diabetic wound healing DOI
Wen Xiang, Jiayi Wei, Jianguo Huang

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141285 - 141285

Published: Feb. 1, 2025

Language: Английский

Citations

0
Construction of pH-responsive hydrogel coatings on titanium surfaces for antibacterial and osteogenic properties DOI Creative Commons
Shan Peng,

Yueru Liu,

Wei Zhao

et al.

Frontiers in Chemistry, Journal Year: 2025, Volume and Issue: 13

Published: Feb. 19, 2025

Infection is one of the leading causes failure in titanium-based implant materials during clinical surgeries, often resulting delayed or non-union bone healing. Furthermore, overuse antibiotics can lead to bacterial resistance. Therefore, developing a novel material with both antimicrobial and osteogenic properties great significance. In this study, chitosan (CS), polydopamine (PDA), peptides (AMPs) HHC36 were applied modify surface titanium, successful preparation composite Ti-PDA-CS/PDA@HHC36 (abbreviated as T-P-C/P@H). CS promotes osteogenesis cell adhesion, providing an ideal microenvironment for repair. PDA enhances material's biocompatibility corrosion resistance, offering adhesion sites, while components exhibit pH-responsive characteristics. The effectively prevents infection, protecting repair from damage. Overall, synergistic effects these T-P-C/P@H not only confer excellent but also improve biocompatibility, new strategy applying implants settings.

Language: Английский

Citations

0
Electrospun metal–organic framework-based nanofibers with natural therapeutic agents for enhanced diabetic wound healing DOI Creative Commons

Soo Ghee Yeoh,

Yun Khoon Liew, May Lee Low

et al.

Discover Materials, Journal Year: 2025, Volume and Issue: 5(1)

Published: March 26, 2025

Language: Английский

Citations

0
Bacterial cellulose nanofiber reinforced self-healing hydrogel to construct a theranostic platform of antibacterial and enhanced wound healing DOI
Wenping Li, Junjie Yu, Qingxue Li

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 136336 - 136336

Published: Oct. 1, 2024

Language: Английский

Citations

2