Advances in adhesive hydrogels applied for ophthalmology: An overview focused on the treatment DOI Creative Commons

Ke Yan,

Qinghe Zhang, Qiu‐Ping Liu

et al.

Theranostics, Journal Year: 2024, Volume and Issue: 15(3), P. 915 - 942

Published: Dec. 2, 2024

Adhesive hydrogels, composed of hydrophilic polymers arranged in a three-dimensional network, have emerged as pivotal innovation ophthalmology due to their ability securely adhere ocular tissues while providing sustained therapeutic effects. The eye, with its delicate structure and specific needs, presents unique challenges for drug delivery tissue regeneration. This review explores the transformative potential adhesive hydrogels addressing these across range conditions, including corneal injuries, cataracts, glaucoma, vitreoretinal disorders, trauma. By detailing mechanisms polymerization adhesion, this paper highlights how materials can be customized ophthalmic applications, offering insights into current use future possibilities. emphasis is placed on clinical significance directions advancing therapy, potentially revolutionizing treatment complex eye diseases.

Language: Английский

Three-step crosslinking dependent self-bending transformation of a nano-spherical mineralized collagen laden 4D printed sodium alginate scaffold for bone regeneration DOI

Song Lv,

Xiaojie Lian, Haonan Feng

et al.

Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: 355, P. 123422 - 123422

Published: Feb. 19, 2025

Language: Английский

Citations

1
Branched Polymer Architecture for Modulating Interactions in Material-Bio Interface DOI

Fahimeh Taghavimandi,

Min Gyu Kim, Mingyu Lee

et al.

Tissue Engineering and Regenerative Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: March 8, 2025

Language: Английский

Citations

1
Comprehensive Review of Hydrogel Synthesis, Characterization, and Emerging Applications DOI Open Access
A. Sathiya Priya,

R. Premanand,

Indhumathi Ragupathi

et al.

Journal of Composites Science, Journal Year: 2024, Volume and Issue: 8(11), P. 457 - 457

Published: Nov. 4, 2024

Hydrogels play a crucial role due to their high-water content and 3D structure, which make them ideal for various applications in biomedicine, sensing, beyond. They can be prepared from variety of biomaterials, polymers, combinations, allowing versatility properties applications. include natural types derived collagen, gelatin, alginate, hyaluronic acid, as well synthetic based on polyethylene glycol (PEG), polyvinyl alcohol (PVA), polyacrylamide (PAAm). Each type possesses distinct properties, such mechanical strength, biodegradability, biocompatibility, tailored wound healing, contact lenses, bioprinting, tissue engineering. The hydrogels mimics environments, promoting cell growth nutrient waste exchange, supports the development functional tissues. serve scaffolds engineering applications, including cartilage bone regeneration, vascular engineering, organ-on-a-chip systems. Additionally, encapsulate deliver therapeutic agents, factors or drugs, specific target sites body. through three primary methods: physical crosslinking, relies non-covalent interactions entanglements hydrogen bonding; chemical forms covalent bonds between polymer chains create stable structure; irradiation-based where UV irradiation induces rapid hydrogel formation. choice crosslinking method depends desired hydrogel. By providing biomimetic environment, facilitate differentiation, support formation, aid regeneration damaged diseased tissues while delivering agents. This review focuses critical advancements processing routes development, summarizing characterization application hydrogels. It also details key healing challenges future perspectives field.

Language: Английский

Citations

7
Fertile Ground for Homeostatic Reformation: Engineered Release Platforms for Enhanced Regenerative Outcomes DOI
Pei Wang, Yan Gong,

Xiansong Wang

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: 106, P. 106740 - 106740

Published: Feb. 21, 2025

Language: Английский

Citations

0
Influence of Photopolymerization on Fabrication of Double Network Conductive Polysuccinimide based Hydrogel: An insight on Structure-property correlation DOI

Kunpeng Chang,

Zhanwen Wang,

Hongliang Wei

et al.

Materials Today Communications, Journal Year: 2025, Volume and Issue: unknown, P. 112803 - 112803

Published: May 1, 2025

Language: Английский

Citations

0
A Novel Surgical Strategy for Repairing Postoperative Xanthelasma Defects Using Lax Upper Eyelid Skin DOI
Tingfeng Xiong, Qing Ye,

Aawrish Khan

et al.

Aesthetic Plastic Surgery, Journal Year: 2025, Volume and Issue: unknown

Published: May 27, 2025

Language: Английский

Citations

0
Advances in adhesive hydrogels applied for ophthalmology: An overview focused on the treatment DOI Creative Commons

Ke Yan,

Qinghe Zhang, Qiu‐Ping Liu

et al.

Theranostics, Journal Year: 2024, Volume and Issue: 15(3), P. 915 - 942

Published: Dec. 2, 2024

Adhesive hydrogels, composed of hydrophilic polymers arranged in a three-dimensional network, have emerged as pivotal innovation ophthalmology due to their ability securely adhere ocular tissues while providing sustained therapeutic effects. The eye, with its delicate structure and specific needs, presents unique challenges for drug delivery tissue regeneration. This review explores the transformative potential adhesive hydrogels addressing these across range conditions, including corneal injuries, cataracts, glaucoma, vitreoretinal disorders, trauma. By detailing mechanisms polymerization adhesion, this paper highlights how materials can be customized ophthalmic applications, offering insights into current use future possibilities. emphasis is placed on clinical significance directions advancing therapy, potentially revolutionizing treatment complex eye diseases.

Language: Английский

Citations

2