Development of Deferoxamine-Functionalized Cyclodextrin Polymer for Targeted Iron Chelation
Published: Jan. 1, 2025
Language: Английский
Rapid and efficient removal of OG dye from wastewater using polypyrrole-coated zinc cobaltite nanorods: RSM optimization and mechanisms insight
Hamid Zouggari,
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Fatima-Zahra Mahir,
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Aida M. Díez
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et al.
Journal of Industrial and Engineering Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 1, 2025
Language: Английский
Development of Deferoxamine‐Functionalized Cyclodextrin Polymer for Targeted Iron Chelation
ChemistryOpen,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 7, 2025
Polymeric
systems
are
used
in
clinical
settings
to
bind
small
molecules
and
ions.
They
show
advantages
pharmacokinetics
reduced
side
effects
compared
low‐molecular‐weight
agents.
In
this
study,
a
cross‐linked
β‐cyclodextrin
polymer
is
functionalized
with
deferoxamine
develop
more
efficient
ways
of
delivering
iron
chelators.
Deferoxamine
well‐known
chelator
treat
overload
conditions.
The
resulting
polymeric
conjugate,
an
equal
complexing
capacity
deferoxamine,
showed
significantly
lower
cytotoxicity
free
all
cancer
cell
lines
studied
(neuroblastoma
SHSY5Y,
breast
MDA‐MB‐231,
ovarian
adenocarcinoma
A2780,
lung
A549).
results
demonstrate
that
the
conjugation
reduces
toxicity
at
same
reveals
potential
deferoxamine‐based
cyclodextrin
conjugates
as
novel
approach
for
targeting
dyshomeostasis.
Language: Английский
Architectonics of a novel carboxylated chitosan-phthalic anhydride/hydroxyapatite composite for organic dye removal: physicochemical properties and adsorption modelling
International Journal of Environmental & Analytical Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 22
Published: May 5, 2025
Language: Английский