Validation of Segmental Bioelectrical Impedance Analysis Compared with Dual Energy X-Ray Absorptiometry to Measure Body Composition in Patients with Obesity-related Heart Failure with Preserved Ejection Fraction DOI Creative Commons

Hannah Salmons,

Syed Imran Ahmed, Hayley Billingsley

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 23, 2024

Background. Appendicular lean mass index (ALMI), a term used to describe appendicular soft tissue measured by dual-energy X-ray absorptiometry (DXA), is major determinant of cardiorespiratory fitness in patients with obesity-related heart failure preserved ejection fraction (HFpEF). Moreover, ALMI can be diagnose sarcopenia and sarcopenic obesity this population. DXA reference standard for assessing body composition, however, segmental single-frequency bioelectrical impedance analysis (SF-BIA) could offer more accessible, portable, cost-effective, radiation-free alternative. To validate SF-BIA composition HFpEF obesity, focus on ALMI. Methods. We analyzed 62 consecutive euvolemic persistent (83.8% female, 60.8± 2.8 years age). both measure fat (AFMI), (FM), fat-free (FFM) kg as % weight, FM index, FFM index. Correlations were assessed using Pearson?s coefficients Bland-Altman plots, while linear regression was performed evaluate proportional bias. Results. Strong, statistically significant correlations found between BIA (r=0.897), AFMI (r=0.864), (r=0.968), FM% (r=0.867), (r=0.954), FFM% (r=0.852), (r=0.97), (r=0.88) (all p<0.001). The demonstrated agreement methods indicated no bias all parameters, except AFMI. Conclusions. Segmental SF-BIA-measured shows strong correlations, appropriate agreements, compared DXA. Considering the central role particularly HFpEF, when not readily available or contraindicated, should considered

Language: Английский

Visceral obesity and HFpEF: targets and therapeutic opportunities DOI
Yilin Li, Zhuofeng Lin,

Yulin Li

et al.

Trends in Pharmacological Sciences, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

1

Insights into the role of obesity in Heart Failure with Preserved Ejection Fraction pathophysiology and management DOI
Brandon Hathorn, Mark J. Haykowsky, Jaime P. Almandoz

et al.

Canadian Journal of Cardiology, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

1

The impact of lifestyle‐based weight loss in older adults with obesity on muscle and bone health: a balancing act DOI Open Access
Tiffany Cortes, Kacey Chae, Colleen M. Foy

et al.

Obesity, Journal Year: 2025, Volume and Issue: unknown

Published: March 10, 2025

Abstract Despite adverse metabolic and functional consequences of obesity (BMI ≥30 kg/m 2 ), clinical recommendations for weight loss (WL) in older adults (65+ years) with remain controversial. Reluctance stems partly from epidemiologic data demonstrating musculoskeletal tissue WL increased risk disability osteoporotic fracture. Randomized controlled trials complement extend knowledge this area showing: (1) lifestyle‐based interventions often yield clinically meaningful (~8%–10%) adults; (2) lean mass is significant, although fat preferential physical performance improved, particularly when combined aerobic resistance training (RT); (3) bone also some evidence that RT can attenuate WL‐associated loss; (4) regain after intervention cessation common, yet gains appear to be maintained. Best practices treating include comprehensive assessment baseline health; patient‐centered goal setting; moderate (i.e., −500 kcal/day) caloric restriction ensuring protein (1–1.2 g/kg/day), calcium (1000–1200 mg/day), vitamin D (800–1000 IU/day) needs are met; incorporation (≥2 days/week) moderate‐intensity weight‐bearing (≥150 min/week); delivery care by a multidisciplinary team. image

Language: Английский

Citations

0

Aerobic, resistance, and specialized exercise training in heart failure with preserved ejection fraction: A state-of-the-art review DOI Creative Commons
Saeid Mirzai,

Uttsav Sandesara,

Mark J. Haykowsky

et al.

Heart Failure Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: May 15, 2025

Language: Английский

Citations

0

Dietary Interventions in Heart Failure With Preserved Ejection Fraction DOI Creative Commons
Hayley Billingsley, Salvatore Carbone, Elissa Driggin

et al.

JACC Advances, Journal Year: 2024, Volume and Issue: 4(1), P. 101465 - 101465

Published: Dec. 17, 2024

Language: Английский

Citations

3

Assessing Static Balance, Balance Confidence, and Fall Rate in Patients with Heart Failure and Preserved Ejection Fraction: A Comprehensive Analysis DOI Creative Commons
Andriana Teloudi, Maria Anifanti, Konstantinos Chatzinikolaou

et al.

Sensors, Journal Year: 2024, Volume and Issue: 24(19), P. 6423 - 6423

Published: Oct. 4, 2024

Chronic heart failure (CHF) is a complex clinical syndrome, associated with frailty, higher fall rates, and frequent hospitalizations. Heart Failure (HF) preserved ejection fraction (HFpEF) defined as condition where patient HF have diagnosis of left ventricular (LVEF) ≥ 50%. The risk HFpEF increases age related to non-cardiovascular mortality. aim this study was evaluate static balance examine the effect task difficulty on discriminating power control between patients (Patients HFpEF) their healthy controls. Moreover, associations parameters, confidence, falls, lean muscle mass, strength were assessed. Seventy two (mean age: 66.0 ± 11.6 years) seventy age- gender-matched individuals 65.3 9.5 participated in study. Participants underwent 30 s bilateral stance (BS) test 20 Tandem-Romberg (TRS) force platform, evaluating Range Standard Deviation Center Pressure (COP) displacement parameters both axes. Balance confidence evaluated by Activities-Specific Confidence (ABC) Scale, number falls during last year recorded. Lower limb measured using an isokinetic dynamometer, isometric leg strength, Sit-to-Stand test. Bioelectrical impedance analysis conducted assess fat mass index, lean%. Patients presented lower BS TRS compared controls (p < 0.05), 21.5% incidence 72.9% 0.05). better descriptor between-group difference. Furthermore, balance, assessed controlled lab conditions, found little if no relationship confidence. Although correlation noted rate age, fat.

Language: Английский

Citations

0

Validation of Segmental Bioelectrical Impedance Analysis Compared with Dual Energy X-Ray Absorptiometry to Measure Body Composition in Patients with Obesity-related Heart Failure with Preserved Ejection Fraction DOI Creative Commons

Hannah Salmons,

Syed Imran Ahmed, Hayley Billingsley

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 23, 2024

Background. Appendicular lean mass index (ALMI), a term used to describe appendicular soft tissue measured by dual-energy X-ray absorptiometry (DXA), is major determinant of cardiorespiratory fitness in patients with obesity-related heart failure preserved ejection fraction (HFpEF). Moreover, ALMI can be diagnose sarcopenia and sarcopenic obesity this population. DXA reference standard for assessing body composition, however, segmental single-frequency bioelectrical impedance analysis (SF-BIA) could offer more accessible, portable, cost-effective, radiation-free alternative. To validate SF-BIA composition HFpEF obesity, focus on ALMI. Methods. We analyzed 62 consecutive euvolemic persistent (83.8% female, 60.8± 2.8 years age). both measure fat (AFMI), (FM), fat-free (FFM) kg as % weight, FM index, FFM index. Correlations were assessed using Pearson?s coefficients Bland-Altman plots, while linear regression was performed evaluate proportional bias. Results. Strong, statistically significant correlations found between BIA (r=0.897), AFMI (r=0.864), (r=0.968), FM% (r=0.867), (r=0.954), FFM% (r=0.852), (r=0.97), (r=0.88) (all p<0.001). The demonstrated agreement methods indicated no bias all parameters, except AFMI. Conclusions. Segmental SF-BIA-measured shows strong correlations, appropriate agreements, compared DXA. Considering the central role particularly HFpEF, when not readily available or contraindicated, should considered

Language: Английский

Citations

0