Wireless, Programmable, and Refillable Hydrogel Bioelectronics for Enhanced Diabetic Wound Healing

Advanced Science, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 14, 2024

Abstract Diabetic wounds, characterized by complex pathogenesis and high infection rates, pose significant challenges in treatment due to prolonged recovery times recurrence often leading severe complications such as amputation death. Traditional dry dressing treatments fail address the unique microenvironment of diabetic wounds tend cause secondary damage frequent replacement. In this study, an electronic‐embedding, drug‐loading hydrogel bioelectronics is reported for accelerating wound healing using a combination programmable pharmaceutical electrostimulative approaches. Encapsulated stretchable biocompatible materials, device capable multiple drug refilling accelerated release modulated on‐board electronics. vivo experiments on model rats confirm device's effectiveness promoting healing. This innovative approach implies potential improving management physical, material, interventions.

Language: Английский

Corticosteroid-loaded chitosan-based in-situ forming gel combined with microneedle technology for improvement of burn eschar wound healing

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 664, P. 124590 - 124590

Published: Aug. 15, 2024

Language: Английский

Preparation and Characterization of IPNs for Controlled Release of 5-Fluorouracil: Evaluation of Possible Use in Wound Dressing

Journal of Polymers and the Environment, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 24, 2024

Language: Английский