Low molecular weight polysaccharide of Tremella fuciformis exhibits stronger antioxidant and immunomodulatory activities than high molecular weight polysaccharide

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 136097 - 136097

Published: Sept. 1, 2024

Language: Английский

---

Polysaccharides with antioxidant activity: Extraction, beneficial roles, biological mechanisms, structure-function relationships, and future perspectives: A review

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 300, P. 140221 - 140221

Published: Jan. 22, 2025

Language: Английский

---

Isolation, In Vitro Antioxidant Capacity, Hypoglycemic Activity and Immunoactivity Evaluation of Polysaccharides from Coriandrum sativum L.

Antioxidants, Journal Year: 2025, Volume and Issue: 14(2), P. 149 - 149

Published: Jan. 27, 2025

Coriander (Coriandrum sativum) is a classical medicinal and edible herb as well spice, but the physicochemical biological properties of its polysaccharides have not been fully studied. In this study, were extracted using an ultrasonic-assisted method purified from fresh coriander, then coriander polysaccharide (CSP) fraction was separated agarose gel Q-Sepharose Fast Flow column. The total sugar content, protein content monosaccharides composition CSPs determined phenol–sulfuric acid method, Coomassie Brilliant Blue HPLC. structural characterization detected ultraviolet spectrophotometry FT-IR spectroscopy. DPPH ABTS free radicals used to explore their antioxidant activities, while inhibitory abilities α-amylase α-glucosidase evaluate hypoglycemic activity. After that, immunomodulatory antitumor activities investigated macrophage RAW264.7 HepG2 cells targets. results showed that contents 66.90 ± 1.44% 1.06 0.32%, respectively. mainly composed fucose, rhamnose, arabinose, galactose, glucose, galacturonic glucuronic acid, with molar ratio 1.13:15.11:9.60:25.98:1.55:44.33:2.29, may be acidic heteropolysaccharide containing pyran rings, α- β-glycosidic bonds acid. Results in vitro experiments IC50 for scavenging 0.759 mg/mL 1.758 mg/mL, respectively; values inhibiting 0.634 2.178 concentration 25~200 μg/mL no obvious toxicity RAW264.7, when treated 100 CSPs, relative cell phagocytosis capacity secreted nitric oxide amount 153.75 12.01% 133.56 5.37%, concentration-dependent ability inhibit growth within test 0.25–2.0 mg/mL. Summarizing results, due excellent antioxidant, anti-tumor expected show good potential comprehensive development food medicine.

Language: Английский

---

Structural characterization, antioxidant activity, and fermentation characteristics of Flammulina velutipes residue polysaccharide degraded by ultrasonic assisted H2O2-Vc technique

Ultrasonics Sonochemistry, Journal Year: 2024, Volume and Issue: 111, P. 107085 - 107085

Published: Sept. 27, 2024

Language: Английский

---

Comparative Study of Pentanema verbascifolium Extracts: Phytochemical Composition, Antioxidant Potential, and Enzyme Inhibition Across Plant Parts

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106607 - 106607

Published: April 1, 2025

Language: Английский

---

High molecular weight polysaccharides from Ganoderma lucidum attenuates inflammatory responses, gut microbiota, and liver metabolomic in lipopolysaccharide-induced liver injury mice

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 138400 - 138400

Published: Dec. 1, 2024

Language: Английский

---