Shrimp Shapes a Nitrite Tolerance Trait via Regulating Autophagy and Apoptosis

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(4), P. 1641 - 1641

Published: Feb. 14, 2025

Nitrite is a significant toxic substance that causes acute toxicity in aquatic animals. However, the molecular mechanisms underlying nitrite tolerance remain largely unidentified. Here, we investigated physiological and transcriptomic profiles of nitrite-sensitive nitrite-tolerant families white shrimp Penaeus vannamei under stress. Exposure to lethal concentration for 72 h caused higher mortality, accumulation, more severe damage both hemolymph hepatopancreas than families. This manifested as hepatic tubular deformation, hepatocyte necrosis, decreased hemocyte counts, lowered phagocytic activity hemocytes, elevated production reactive oxygen species (ROS), AKP enzyme activity. Furthermore, analysis revealed an upregulation protein processing endoplasmic reticulum (ER) families, triggering apoptosis- autophagy-related pathways hemocytes upon exposure. Additionally, TUNEL staining transmission electron microscopy (TEM) experiments tolerant may mitigate by modulating autophagy apoptosis. Collectively, our results provide valuable foundation exploring shrimp, which could facilitate targeted breeding germplasm with enhanced aquaculture.

Language: Английский

Managing freshwater invasive mussel biofouling: Insights into byssal adhesion on underwater surfaces

Journal of Environmental Management, Journal Year: 2025, Volume and Issue: 380, P. 124965 - 124965

Published: March 13, 2025

Language: Английский

Genetic parameter estimation of tolerance traits for ammonia‑nitrogen and nitrite‑nitrogen in Urechis unicinctus

Aquaculture, Journal Year: 2025, Volume and Issue: unknown, P. 742649 - 742649

Published: April 1, 2025

Language: Английский