Biochanin A Mitigates Colitis by Inhibiting Ferroptosis-Mediated Intestinal Barrier Dysfunction, Oxidative Stress, and Inflammation via the JAK2/STAT3 Signaling Pathway
Beiying Deng,
No information about this author
Kunpeng Wang,
No information about this author
Haodong He
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et al.
Phytomedicine,
Journal Year:
2025,
Volume and Issue:
unknown, P. 156699 - 156699
Published: March 1, 2025
Language: Английский
Huangqin decoction alleviated irinotecan-induced diarrhea by inhibiting endoplasmic reticulum stress through activating AMPK/mTOR-mediated autophagy
Yunjing He,
No information about this author
Lei Feng,
No information about this author
Yujie Gao
No information about this author
et al.
Journal of Ethnopharmacology,
Journal Year:
2025,
Volume and Issue:
unknown, P. 119790 - 119790
Published: April 1, 2025
Language: Английский
Intestinal mucus barrier: A potential therapeutic target for IBD
Autoimmunity Reviews,
Journal Year:
2024,
Volume and Issue:
24(2), P. 103717 - 103717
Published: Dec. 9, 2024
Language: Английский
Hymenolepis nana antigens alleviate ulcerative colitis by promoting intestinal stem cell proliferation and differentiation via AhR/IL-22 signaling pathway
X. Cui,
No information about this author
Yi Cheng,
No information about this author
Hongyan Wang
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et al.
PLoS neglected tropical diseases,
Journal Year:
2024,
Volume and Issue:
18(12), P. e0012714 - e0012714
Published: Dec. 12, 2024
Ulcerative
colitis
(UC)
is
a
chronic
inflammatory
bowel
disease
with
an
unknown
etiology
and
difficult
to
treat.
Studies
have
shown
that
some
helminths
their
associated
products
therapeutic
potential
in
controlling
or
preventing
diseases.
This
study
investigate
the
mitigation
effects
of
Hymenolepis
nana
antigens
(HnAg)
on
UC
model.
HnAg
significantly
improved
activity
index,
colon
length,
colonic
pathological
damage
mice
dextran
sulfate
sodium
(DSS)-induced
colitis.
intervention
could
protect
number
goblet
cells
enhance
expression
tight
junction
proteins
mucins,
thereby
improving
intestinal
barrier
integrity.
attenuated
small
organoid
stimulated
stem
proliferation
DSS-induced
mouse
inflammation
The
protective
mechanism
might
be
related
activation
aryl
hydrocarbon
receptor
(AhR)/IL-22
signaling
pathway,
which
regulates
function
promotes
differentiation
cells.
In
conclusion,
has
effect
mice.
Our
provides
new
approach
for
alleviating
by
its
products.
Language: Английский
Effects and mechanism of combination of Platycodon grandiflorum polysaccharides and Platycodon saponins in the treatment of chronic obstructive pulmonary disease rats through the gut-lung axis
Journal of Ethnopharmacology,
Journal Year:
2024,
Volume and Issue:
unknown, P. 119305 - 119305
Published: Dec. 1, 2024
Language: Английский