Chemosphere,
Journal Year:
2023,
Volume and Issue:
330, P. 138695 - 138695
Published: April 18, 2023
Along
with
bisphenol-A
(BPA),
conventional
phthalate
esters
(PAEs)
have
been
reported
as
environmental
hormones,
despite
their
functional
usefulness
plasticizers.
Nevertheless,
they
are
frequently
found
in
various
products,
including
children's
utensils
and
toys
made
of
poly
(vinyl
chloride).
This
is
tremendously
important
because
PAEs
harmful
to
infants.
In
addition,
gel/slime-type
alcohol)
currently
popular
for
developing
infant'
tactile
senses.
this
study,
we
developed
a
method
qualitatively
quantitatively
detect
mimicking,
infants
playing
them
bathtub.
As
result,
1,2-cyclohexanedicarboxylic
acid
diisononyl
ester
(DINCH),
one
the
PAE
alternatives,
transferred
into
water
from
was
detected
most
commonly
(108-719
μg
g-1;
0.01-0.07
wt%)
among
PAEs.
The
DINCH
levels
were
below
universally
accepted
(0.1
wt%).
However,
amount
could
still
be
toxic,
accordance
toxicity
tests
using
fleas.
Furthermore,
unpleasant
odors
emitted
when
containing
toxic
volatile
organic
compounds
unpacked.
first
study
develop
analyze
determine
that
alternatives
cannot
unconditionally
regarded
safe
chemicals.
Therefore,
revised
standards
regulating
must
reconsidered.
Current Neuropharmacology,
Journal Year:
2024,
Volume and Issue:
22(11), P. 1870 - 1898
Published: March 29, 2024
Environmental
exposures
to
non-biodegradable
and
biodegradable
plastics
are
unavoidable.
Microplastics
(MPs)
nanoplastics
(NPs)
from
the
manufacturing
of
(primary
sources)
degradation
plastic
waste
(secondary
can
enter
food
chain
directly
or
indirectly
and,
passing
biological
barriers,
could
target
both
brain
gonads.
Hence,
worldwide
diffusion
environmental
contamination
(PLASTAMINATION)
in
daily
life
may
represent
a
possible
potentially
serious
risk
human
health.
Environmental Pollution,
Journal Year:
2023,
Volume and Issue:
341, P. 122946 - 122946
Published: Nov. 15, 2023
Plastics
contain
a
mixture
of
chemical
additives
that
can
leach
into
the
environment
and
potentially
cause
harmful
effects
on
reproduction
endocrine
system.
Two
these
chemicals,
N-butyl
benzenesulfonamide
(NBBS)
triphenyl
phosphate
(TPHP),
are
among
top
30
organic
chemicals
detected
in
surface
groundwater
currently
placed
international
watchlist
for
evaluation.
Although
bans
have
been
legacy
pollutants
such
as
diethylhexyl
phthalate
(DEHP)
dibutyl
(DBP),
their
persistence
remains
concern.
This
study
aimed
to
examine
impact
plastic
additives,
including
NBBS,
TPHP,
DBP,
DEHP,
reproductive
behaviour
male
fertility
marine
amphipod
Echinogammarus
marinus.
Twenty
precopulatory
pairs
E.
marinus
were
exposed
varying
concentrations
four
test
assess
pairing
behaviour.
A
high-throughput
methodology
was
developed
optimised
record
contact
time
re-pair
within
15
min
additional
point
observations
96
h.
The
found
low
levels
DEHP
prolonged
re-pairing
amphipods
proportion
reduced
drastically
with
success
ranging
from
75%
100%
control
group
0%–85%
groups
at
Sperm
count
declined
by
40%
60%
50
μg/l
500
DBP
groups,
respectively,
whereas
TPHP
resulted
significantly
lower
sperms
group.
Animals
NBBS
showed
high
interindividual
variability
all
groups.
Overall,
this
provides
evidence
disrupt
mechanisms
sperm
counts
environmentally
relevant
concentrations.
Our
research
also
demonstrated
usefulness
mechanism
sensitive
endpoint
ecotoxicity
assessments
proactively
mitigate
population-level
aquatic
environment.
Phthalates
(PAEs)
are
one
of
the
most
widely
used
compounds
in
polymer
products,
commonly
as
additives
food
packaging,
personal
care
insecticides,
and
agricultural
films.
In
plastic
industry,
they
mainly
plasticizers
to
increase
flexibility
durability
polyvinyl
chloride
(PVC)
plastics.
Due
noncovalent
binding
PAEs
with
can
migrate
from
interior
product
through
wear
leaching,
gradually
continuously
releasing
into
environment,
causing
widespread
pollution
environmental
media
such
atmosphere,
water,
soil,
sediment,
leading
increasing
exposure
risk
human.
Some
research
has
shown
that
have
a
chemical
structure
similar
sex
hormones
endocrine-disrupting
effects,
affecting
fertility
reproductive
health
both
females
males.
addition,
neurotoxicity,
hepatotoxicity,
carcinogenicity
been
reported,
so
classified
harmful
chemicals
(EDCs)
emerging
pollutants.
However,
challenge
is
appearance
these
does
not
exist
single
compound,
typically
exposed
people
form
mixtures.
Because
instability
PAEs,
even
be
metabolized
by
organisms
produce
more
toxic
metabolites.
Although
extensive
studies
on
several
there
limited
understanding
their
interactions.
Therefore,
this
chapter
introduces
combined
toxicological
cases
PAE
co-exposure.
