α-Ketoglutarate modulates the mechanisms of toxicity in crucian carp kidneys chronically exposed to NaHCO3: Metabolomics insights

Comparative Biochemistry and Physiology Part D Genomics and Proteomics, Journal Year: 2025, Volume and Issue: 55, P. 101466 - 101466

Published: March 4, 2025

Language: Английский

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Influence of anti-androgen cyproterone acetate on sperm characteristics, testosterone level, testicular and liver histology in male goldfish (Carassius auratus)

Emerging contaminants, Journal Year: 2025, Volume and Issue: unknown, P. 100507 - 100507

Published: April 1, 2025

Language: Английский

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Impact of continuous Triazophos exposure on Labeo rohita: Physiological, biochemical, and histological alterations and IBRv2 index assessment

Pesticide Biochemistry and Physiology, Journal Year: 2024, Volume and Issue: 204, P. 106043 - 106043

Published: July 23, 2024

Language: Английский

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Toxic Effects of 4‐Bromodiphenyl Ether (BDE‐3) on Antioxidant Enzymes, Cell Viability, Histology and Biomolecules in Zebrafish Embryo‐Larvae

Journal of Applied Toxicology, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 4, 2024

ABSTRACT Polybrominated diphenyl ethers (PBDEs) are a class of flame retardants that being used widely in industrial and consumers products such as plastics, electronics, furniture, textiles so forth. They can undergo debromination process to form less brominated ethers, which bioaccumulative, more volatile toxic nature. The current study was conducted reveal the biochemical, apoptotic, histopathological, ultrastructural biomolecular (ATR‐FTIR) toxicity 4‐bromodiphenyl ether (BDE‐3) zebrafish larvae. After 96‐h LC 50 determination, embryos were exposed sublethal concentrations BDE‐3, is, 0.79 1.59 mg/L. MDA content found be significantly increased BDE‐3 larvae whereas FRAP activity decreased. catalase (CAT), glutathione‐S‐transferase (GST) acetylcholinesterase (AChE) observed increased, decreased superoxide dismutase (SOD) reported after exposure cell viability exposure. Histopathological alterations also changes biomolecules DNA protein revealed via ATR‐FTIR analysis. present investigation will help understand nature could utilised assess environmental risk.

Language: Английский

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Assessing the effects of cadmium on antioxidant enzymes and histological structures in rainbow trout liver and kidney

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Nov. 10, 2024

Cadmium contamination in aquatic environments poses severe risks to organisms, particularly fish, where cadmium accumulation tissues can lead compromised organ functionality and reproductive issues. The present study aimed assess the effects of (Cd) exposure on key biomarkers oxidative stress, DNA damage, apoptosis, enzyme activity liver kidney rainbow trout (Oncorhynchus mykiss). Specifically, measured 8-hydroxy-2-deoxyguanosine (8-OHdG) levels, caspase-3 activation, acetylcholinesterase (AChE) activity, stress indicators (ONOO

Language: Английский

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Genotoxic, biochemical, cytotoxic and biomolecular alterations in the early-life stage of zebrafish exposed to diphenyl ether

Drug and Chemical Toxicology, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 12

Published: Nov. 28, 2024

Diphenyl ether (DE) is a chemical compound being used in number of industries such as soap, detergents, perfumes, adhesive, dyes, herbicides and flame retardant plastics, rubbers textiles, etc. DE the final debromination product polybrominated diphenyl ethers (PBDEs) under anaerobic conditions. The present investigation evaluated genotoxic, biochemical, histopathological, ultrastructural (SEM) biomolecular (ATR-FTIR) changes zebrafish larvae after exposure. After determination 96 h LC

Language: Английский

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Elevated Urinary Levels of Primary Aromatic Amines in Residents from E-Waste Dismantling Area: Associations with Oxidative Stress and Kidney Injury

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 485, P. 136821 - 136821

Published: Dec. 9, 2024

Language: Английский

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