Impact of New Ventilation and Hemodynamic Support Strategies on the Recovery of Critically Ill Patients with Acute Respiratory Distress Syndrome due to Sepsis: A Systematic Review DOI Creative Commons

Luisa Paulina Chafla Romero,

Ana Beatriz Batista e Silva,

Mónica Alexandra Caiza Asitimbay

et al.

Salud Ciencia y Tecnología, Journal Year: 2025, Volume and Issue: 5, P. 1320 - 1320

Published: Jan. 1, 2025

Acute Respiratory Distress Syndrome (ARDS) is a complication caused by sepsis and present burden in critical care with high mortality limited effective treatments. Advances ventilation hemodynamic support offer potential to improve recovery. Our aim systematically evaluate impact of new strategies on the recovery critically ill patients ARDS due sepsis. The research conducted Web Science, PubMed, Embase, Cochrane Library from January 2000 December 2023. We selected randomized controlled trials observational studies that looked at adult as main cause were focus inclusion criteria. Advanced fluid management, extracorporeal membrane oxygenation (ECMO) lung-protective among interventions. Survival rates, length mechanical breathing improvements rates outcomes examined. Low tidal volume reduced 31% 40% ventilator-induced lung injury. Research stated prone positioning improved moderate-to-severe ARDS. documented ECMO offered survival benefits refractory cases while conservative ventilator days without impacting mortality. monitoring titration perfusion Certain interventions such high-frequency oscillatory ventilation, showed benefit or increased risk. Emerging enhance sepsis-induced through individualized care. Future should refine these optimize minimizing risks.

Language: Английский

Applicability of mouse models for induction of severe acute lung injury DOI

Ana Paula Ferreira Leal,

Valentina Nieto Marín,

Vinícius Varzim Cabistany

et al.

Pulmonary Pharmacology & Therapeutics, Journal Year: 2024, Volume and Issue: 86, P. 102316 - 102316

Published: July 26, 2024

Language: Английский

Citations

4

Macrophage pyroptosis and its crucial role in ALI/ARDS DOI Creative Commons

Yuju Cai,

Luorui Shang,

Fangyuan Zhou

et al.

Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 14, 2025

Acute lung injury(ALI)/acute respiratory distress syndrome(ARDS) is a severe clinical syndrome characterized by high morbidity and mortality, primarily due to injury. However, the pathogenesis of ALI/ARDS remains complex issue. In recent years, role macrophage pyroptosis in injury has garnered extensive attention worldwide. This paper reviews mechanism pyroptosis, discusses its ALI/ARDS, introduces several drugs intervening measures that can regulate influence progression ALI/ARDS. By doing so, we aim enhance understanding provide novel insights for treatment.

Language: Английский

Citations

0

SARS-CoV-2: A synergy to the Alzheimer’s disease DOI
Khaja Moinuddin Shaik, Deepak Kumar, Pirangi Srikanth

et al.

Journal of NeuroVirology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 25, 2025

Language: Английский

Citations

0

Mechanisms of pulmonary microvascular endothelial cells barrier dysfunction induced by LPS: The roles of ceramides and the Txnip/NLRP3 inflammasome DOI

Huijuan Ouyang,

Yi Wang, Jie Wu

et al.

Microvascular Research, Journal Year: 2023, Volume and Issue: 147, P. 104491 - 104491

Published: Jan. 26, 2023

Language: Английский

Citations

10

Impact of New Ventilation and Hemodynamic Support Strategies on the Recovery of Critically Ill Patients with Acute Respiratory Distress Syndrome due to Sepsis: A Systematic Review DOI Creative Commons

Luisa Paulina Chafla Romero,

Ana Beatriz Batista e Silva,

Mónica Alexandra Caiza Asitimbay

et al.

Salud Ciencia y Tecnología, Journal Year: 2025, Volume and Issue: 5, P. 1320 - 1320

Published: Jan. 1, 2025

Acute Respiratory Distress Syndrome (ARDS) is a complication caused by sepsis and present burden in critical care with high mortality limited effective treatments. Advances ventilation hemodynamic support offer potential to improve recovery. Our aim systematically evaluate impact of new strategies on the recovery critically ill patients ARDS due sepsis. The research conducted Web Science, PubMed, Embase, Cochrane Library from January 2000 December 2023. We selected randomized controlled trials observational studies that looked at adult as main cause were focus inclusion criteria. Advanced fluid management, extracorporeal membrane oxygenation (ECMO) lung-protective among interventions. Survival rates, length mechanical breathing improvements rates outcomes examined. Low tidal volume reduced 31% 40% ventilator-induced lung injury. Research stated prone positioning improved moderate-to-severe ARDS. documented ECMO offered survival benefits refractory cases while conservative ventilator days without impacting mortality. monitoring titration perfusion Certain interventions such high-frequency oscillatory ventilation, showed benefit or increased risk. Emerging enhance sepsis-induced through individualized care. Future should refine these optimize minimizing risks.

Language: Английский

Citations

0