Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
11(20), P. 5806 - 5812
Published: Jan. 1, 2024
An
unprecedented
copper-catalyzed
oxidative
dehydrogenative
[3
+
2]
annulation
of
oximes
with
α-amino
ketones
involving
dehydroxylation
toward
3-aminopyrroles
is
disclosed.
Green Chemistry,
Journal Year:
2024,
Volume and Issue:
26(12), P. 7331 - 7336
Published: Jan. 1, 2024
A
novel
photocatalytic
acylation
strategy
was
developed
harnessing
tetrabutylammonium
decatungstate
(TBADT)
as
a
hydrogen
atom
transfer
(HAT)
photocatalyst
to
facilitate
the
direct
coupling
of
aldehydes
with
N-heterocycles
at
ambient
temperature.
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(25), P. 5263 - 5268
Published: June 14, 2024
A
green
and
sustainable
electrochemical
oxidative
cyclization
of
enaminones
with
thioamides
under
metal-
oxidant-free
conditions
has
been
developed,
providing
an
efficient
approach
for
thiazole
synthesis.
Furthermore,
1,2,4-thiadiazoles
can
be
selectively
accessed
via
the
dimerization
in
absence
enaminones.
Green Chemistry,
Journal Year:
2024,
Volume and Issue:
26(8), P. 4600 - 4608
Published: Jan. 1, 2024
A
metal-free
and
catalyst-free
strategy
is
reported
to
achieve
N–H
insertions
by
coupling
N
-tosylhydrazones
with
diverse
amines
including
aminopyridines,
anilines,
aliphatic
amines,
other
nucleophiles
such
as
imidazoles
indoles.
Organic Chemistry Frontiers,
Journal Year:
2023,
Volume and Issue:
11(1), P. 135 - 141
Published: Nov. 21, 2023
A
visible-light-induced
one-pot
three-component
reaction
of
cycloketone
oxime
esters,
NH-sulfoximines,
and
alkenes
was
developed
for
the
difunctionalization
alkenes.
Organic Letters,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 24, 2025
A
copper-catalyzed
[4
+
2]
annulation
protocol
from
readily
available
α,β-unsaturated
ketoximes
and
dialkyl
acetylenedicarboxylates
has
been
achieved.
The
approach
enables
the
expedient
construction
of
a
series
structurally
new
highly
substituted
pyridines
with
good
functional
group
tolerance.
Organic Letters,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 26, 2025
The
catalytic
asymmetric
multicomponent
acylation/rearrangement/cyclization
of
alkenylfurans
with
acyl
oxime
esters/arylamines
or
esters/arylamines/hydroxylamine
has
been
developed.
This
method
employs
synergistic
photoredox/Brønsted
acid
catalysis,
enabling
the
efficient
and
versatile
synthesis
multifunctionalized
[3.2.1]
[4.2.1]
bicyclic
bridged
compounds
in
high
yields
excellent
diastereo-
enantioselectivities.
A
synergistic
I2/secondary
amine
catalysis
has
been
developed
for
the
modular
assembly
of
2,2'-bipyridines,
employing
oxime
esters
and
enals
as
readily
available
starting
materials.
This
method
demonstrates
a
good
substrate
scope
functional
group
tolerance
can
easily
afford
series
structurally
new
2,2'-bipyridines
in
moderate
to
yields.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(37), P. 6886 - 6890
Published: Sept. 7, 2023
Herein,
we
have
developed
an
atom-
and
step-economic
three-component
cascade
reaction
that
enables
a
modular
platform
for
the
synthesis
of
pyrrolo[2,3-c]quinoline
compounds
through
ring-expansion/cyclization
by
way
novel
N1–C2
cleavage
indoles.
The
metal-free
catalytic
system
exhibits
broad
functional
group
tolerance.