The Latest Progress in the Chemistry of Daphniphyllum Alkaloids DOI Creative Commons

Lujuan Chen,

Chao Lv, Yan Meng

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(23), P. 5498 - 5498

Published: Nov. 21, 2024

alkaloids (DAs) are interesting molecules with rich molecular skeletons and diverse biological activities. Since their discovery, phytochemists have isolated, purified, identified more than 350 DAs. Synthetic chemists, attracted by the structure activity of DAs, accomplished many elegant synthetic jobs. Herein, we summarize work on isolation, structural identification, bioactivity testing, synthesis DAs from 2018 to 2023, aim providing a reference for future studies.

Language: Английский

Synthesis of the AB Ring System of Daphniphyllum Alkaloid Daphniglaucin C DOI
Xiaofeng Zhang, Aggeliki Roumana,

Hai-Kang Mao

et al.

Chinese Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: 45(3), P. 925 - 925

Published: Jan. 1, 2025

Language: Английский

Citations

0
Total Synthesis of Daphniphyllum Alkaloids: (+)-Daphlongamine E, (+)-Calyciphylline R, and (–)-10-Deoxydaphnipaxianine A DOI
Yan Zhang, Yuye Chen, Jing Xu

et al.

Synthesis, Journal Year: 2024, Volume and Issue: 56(08), P. 1273 - 1284

Published: Jan. 12, 2024

Abstract Here, we wish to describe our detailed efforts in the total synthesis of three calyciphylline A-type alkaloids, namely (+)-daphlongamine E, (+)-calyciphylline R, and (–)-10-deoxydaphnipaxianine A. Important steps approach include a Pt-catalyzed nitrile hydration, Babler–Dauben rearrangement, novel selective amide reduction tactic, an oxidative Nazarov cyclization via unfunctionalized tertiary divinyl carbinol (TDC).

Language: Английский

Citations

2
Synthetic Study toward Daphnimacropodines DOI

Hai-Kang Mao,

Qian Wang,

Sujun Xie

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 4, 2024

Daphnimacropodines A-C are members of a small but structurally distinct subfamily

Language: Английский

Citations

1
The Latest Progress in the Chemistry of Daphniphyllum Alkaloids DOI Creative Commons

Lujuan Chen,

Chao Lv, Yan Meng

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(23), P. 5498 - 5498

Published: Nov. 21, 2024

alkaloids (DAs) are interesting molecules with rich molecular skeletons and diverse biological activities. Since their discovery, phytochemists have isolated, purified, identified more than 350 DAs. Synthetic chemists, attracted by the structure activity of DAs, accomplished many elegant synthetic jobs. Herein, we summarize work on isolation, structural identification, bioactivity testing, synthesis DAs from 2018 to 2023, aim providing a reference for future studies.

Language: Английский

Citations

0