An environment-responsive platform based on acid-resistant metal organic framework for efficient oral insulin delivery DOI
Yingnan Zhu, Ruikang Zhang, Wenwen Gao

et al.

Journal of Controlled Release, Journal Year: 2024, Volume and Issue: 377, P. 540 - 552

Published: Nov. 29, 2024

Language: Английский

Enhanced diabetic foot ulcer treatment with a chitosan-based thermosensitive hydrogel loaded self-assembled multi-functional nanoparticles for antibacterial and angiogenic effects DOI
Zhiwei Wu, Weiwei Wu, Chi Zhang

et al.

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 347, P. 122740 - 122740

Published: Sept. 12, 2024

Language: Английский

Citations

8
Injectable dual-network hydrogel for phototherapy and immunomodulation in the treatment of MRSA-infected and diabetic wound DOI

Shengfei Bao,

Aodi Jiang,

Peng Li

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 163026 - 163026

Published: April 1, 2025

Language: Английский

Citations

0
Ratiometric Fluorescent Sensors for Real-Time Monitoring Cellular Autophagy Levels during Diabetic Wound Healing DOI
Fei Yang,

Xiuzhu Huo,

Xiaoyu Fu

et al.

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: April 11, 2025

Hard-healing wounds are a serious issue faced by diabetic patients, and the cellular autophagy level is closely related to wound healing progress. However, it difficult monitor real-time levels in living organisms. In this work, we provided new fluorescent sensor IN-NH2 based on modification of 2-substituted quinoline, giving an excellent ability quantify pH fluctuation lysosomes during autophagy. This was successfully applied monitoring model rats, showing potential for exploring internal mechanism between disease progression.

Language: Английский

Citations

0
Nanozymes in Biomedical Applications: Innovations Originated From Metal‐Organic Frameworks DOI
Yuewu Zhao, Junjie Cheng, Zhen Li

et al.

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 25, 2024

Abstract Nanozymes exhibit significant potential in medical theranostics, environmental protection, energy development, and biopharmaceuticals due to their exceptional catalytic performance. Compared with natural enzymes, nanozymes have the advantages of simple preparation purification, convenient production low cost. Therefore, it is very important prepare quickly efficiently, which not only helps expand application scope, but also can further exert great various fields. Metal‐organic frameworks (MOF) materials serve as versatile substrates for constructing nanozymes, offering unique like adjustable structure, high specific surface area, porous channels. MOF coordination nodes constructed from metal ions or clusters properties that be leveraged tailor nanozyme characteristics different applications. This review describes analyzes recent methods using materials, explores prospects biomedicine. By expounding techniques biomedical applications this aims inspire researchers develop innovative explore new directions.

Language: Английский

Citations

3
An environment-responsive platform based on acid-resistant metal organic framework for efficient oral insulin delivery DOI
Yingnan Zhu, Ruikang Zhang, Wenwen Gao

et al.

Journal of Controlled Release, Journal Year: 2024, Volume and Issue: 377, P. 540 - 552

Published: Nov. 29, 2024

Language: Английский

Citations

0