Concordance of maternal and cord blood SARS-COV-2 immunoglobulin seropositivity after COVID-19 infection or vaccination in pregnancy

Journal of Neonatal-Perinatal Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 5, 2025

Objective To assess maternal antibody response to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection during pregnancy and subsequent transplacental transfer in cord blood. Study Design This is a prospective cohort study of Disease 2019 (COVID-19) polymerase chain reaction (PCR) positive pregnant women their newborns. SARS-CoV-2 PCR (+) were enrolled, with (−) as control. Maternal blood was obtained at enrollment collected delivery. Baseline infant characteristics neonatal outcomes collected. Samples analyzed using coronavirus antigen microarray containing immunologically significant antigens from (including nucleocapsid protein [NP], spike [S], S1, S2, receptor-binding domain [RBD]) which can detect immunoglobulin G (IgG) M (IgM). Results Thirty-seven maternal-cord paired samples for IgG or IgM antibodies; 15 out 20 14 17 mothers positive. the received COVID-19 vaccine pregnancy. Difference between seropositivity naturally infected versus vaccinated significant, 75% 100% ( p = 0.043). antibodies detected 10 but none Conclusions Excellent concordance exist Significantly higher SARS-COV-2 found mothers.

Language: Английский

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HUBUNGAN PENGETAHUAN IBU HAMIL TENTANG COVID-19 DENGAN PERILAKU PENCEGAHAN PENULARAN COVIT-19

JKM (Jurnal Kebidanan Malahayati), Journal Year: 2021, Volume and Issue: 7(3), P. 432 - 440

Published: July 31, 2021

Background Knowledge is the basis for pregnant women to do one behavior, presence of Covid-19 makes have be able make prevention efforts, pregnancy hormones a woman vulnerable group corona virus, therefore must good knowledge so that behavior in effort prevent Covid-19. Purposes assess about and relationship between behavior. Methods This study used cross sectional design. The population all at Arsy Media Clinic, Cirebon Regency. Sampling using Acidal sampling. data taken are primary obtained through questionnaire given 40 women. correlation test Chi-Square. Research Results Most poor All this showed positive attitude, namely by answering answers carefully, calmly efforts improve health. Pregnant bad preventive against transmission. There significant regarding with value (p = 0.000). Conclusion It was found respondents studied, them had attitude towards who show actions Suggestion Future research expected examine more deeply attitudes better methods. Keywords: Knowledge, Behavior, Women, ABSTRAK Latar Belakang Pengetahuan merupakan dasar ibu hamil melakukan salah suatu perilaku, adanya menjadikan harus mampu upaya pencegahan, perubahan sistem imun yang terjadi pada kehamilan dapat membuat seorang menjadi kelompok rentan terpaparnya oleh karena itu seseorang mempunyai pengetahuan baik agar mampunyai perilaku dalam pencegahan Covid-19.Tujuan Penelitian untuk mengetahui hubungan antara dengan pencegahannya.Metode ini menggunakan desain sectional. Populasi seluruh di Klinik Kabupaten sebesar 1.440 hamil. Pengambilan sampel Acidental sampling sebanyak responden. Data diambil primer didapat melalui kuesioner diberikan kepada Uji Korelasi digunakan adalah Chi-Square.Hasil Sebagian besar (80%) tidak mengenai Seluruh penelitian menunjukkan sikap positif yaitu menrespon jawaban hati-hati, tenang dan usaha peningkatan kesehatan. Mayoritas Ibu Perilaku terhadap penularan Terdapat signifikan perlaku nilai (p=0,000).Kesimpulan Didapatkan bahwa Dari responden diteliti, seluruhnya tindakan Covid-19.Saran peneliti selanjutnya diharapkan mengkaji lebih metode baik. Kata Kunci : Pengentahuan, Perilaku, Hamil,

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Risk Factor of Vitamin-D Deficiency in Pregnant Women with COVID-19 Infection: Comprehensive Meta-Analysis and Systematic Review

Asian Journal of Health Research, Journal Year: 2024, Volume and Issue: 3(1), P. 87 - 93

Published: April 10, 2024

Introduction: It has been suggested that coronavirus infection (COVID-19) in pregnant women may be influenced by vitamin D deficiency (VDD). The physiological changes brought on pregnancy, and the body's partial immune suppression make more susceptible to viral infections. Therefore, this review aims synthesize current information link between levels risk of COVID-19 women. Material Methods: A systematic search is conducted PubMed, ScienceDirect, Google Scholar. Articles retrieved were screened based PRISMA 2020 guidelines. Studies assessed effect with considered for review. Odds ratios their 95 percent confidence intervals (CI) from a meta-analysis using random-effects model reported. Results: Three eligible studies relevant relationship (n=1005). metanalysis showed was 1.8 times (95% interval, OR 1.72 1.88; p=0.0005) likely infected COVID-19. Conclusion: According our results, increase infection. we recommend adequate prevent its severity.

Language: Английский

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Transmissão vertical e SARS-COV-2: o que sabemos até agora?

Brazilian Journal of Health Review, Journal Year: 2020, Volume and Issue: 3(4), P. 9128 - 9141

Published: Jan. 1, 2020

A doença nomeada COVID-19 pela Organização Mundial da Saúde, foi declarada pandemia em 11 de Março 2020. Preocupa-se que haja possibilidade transmissão vertical devido à alta infectividade do SARS-CoV-2 e a reconhecida imunossupressão gestacional. Assim, o objetivo presente estudo revisar as evidências científicas sobre na COVID-19. Foi realizada uma revisão integrativa nas bases dados PubMed, Lilacs, Science Direct Scielo por meio dos descritores "pregnancy" "COVID-19" até 14 junho 2020, selecionando aqueles abordassem vertical. Dentre os 23 artigos escolhidos, observou-se risco materno-fetal é plausível – já poucos relatam presença vírus tecido placentário mas parece incomum. É possível seja encontrado menor proporção nasofaringe neonato, todavia, análises líquido amniótico, sangue cordão umbilical leite materno não evidenciaram viral, momento.

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Features of the Clinical Current of Coronavirus Infection (COVID-19) Among Newborns

Клиническая инфектология и паразитология, Journal Year: 2023, Volume and Issue: 12(2), P. 131 - 141

Published: Sept. 2, 2023

По сей день врачей всего мира беспокоят вопросы, касающиеся COVID-19-инфекции. Ряд вопросов имеется и у неонатологов. С учетом полученных ранее данных о повышении перинатальной смертности, возрастании частоты преждевременных родов, выкидышей, случаев преэклампсии экстренного кесарева сечения, если во время беременности имелись SARS MERS, вполне закономерна постановка вопроса возможном неблагоприятном влиянии новой коронавирусной инфекции COVID-19 на внутриутробное развитие плода, исход состояние здоровья новорожденного после рождения в неонатальном периоде. Случаи вертикального пути передачи новорожденным редки составляют примерно 2%. Играют роль передаче материнские факторы. Риск от матери ребенку возрастает при тяжелом течении беременной. Для новорожденных характерна вариабельность клинической картины бессимптомной до респираторных кардиоваскулярных нарушений, нарушения терморегуляции, диспепсических расстройств: срыгивание, рвота, парез кишечника, диарея. Doctors around the world are concerned about infection. Neonatologists also have a number of questions. Previous data been obtained on an increase in perinatal mortality, frequency preterm birth, miscarriage, cases preeclampsia and emergency caesarean section if virus or MERS were present during pregnancy. The question arises possible adverse effects intrauterine development fetus, pregnancy outcome health newborn after birth neonatal period. Cases vertical transmission SARS-СoV-2 to newborns rare account for Maternal factors play role risk mother-to-child increases with severe pregnant woman. Neonatal infection is characterized by clinical variability from asymptomatic respiratory cardiovascular disorders; violations thermoregulation; dyspeptic disorders: regurgitation, vomiting, intestinal paresis, diarrhea.

Language: Русский

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PENGETAHUAN, SIKAP DAN PERILAKU IBU HAMIL SELAMA PANDEMI COVID-19

Jurnal Perawat Indonesia, Journal Year: 2023, Volume and Issue: 7(2), P. 1363 - 1370

Published: Aug. 30, 2023

Kehamilan adalah suatu proses fisiologi seorang wanita untuk meneruskan keturunan, Tujuan Penelitian ini melihat karakteristik ibu hamil dalam menjalani kehamilannya selama pandemic di aceh barat daya privinsi aceh, metode penelitian : adapun jenis bersifat deskriptif dengan pendekatan cross sectional desain. Sampel pada berjumlah 124 sebagai responden pemilihan sampel snowball sampling. Analisa data dilakukan menggunakan uji statistic spss, hasil didapatkan domisili sebesar 86,7%, adanya usia berusia 26 – 30 tahun 44,3%, tingkat pendidikan tinggi 47,8%, kehamilan mayoritas trimester 2 41,6% kunjungan kali 40,7%, pengetahuan 70,9%, sikap positif 61,1% dan perilaku baik 61,9%. Direkomendasikan kepada tenaga pelayanan kesehatan agar dapat memfasilitasi khusus media elektronik guna mempermudah ke kesehatan.

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