Coordination Chemistry Reviews,
Journal Year:
2022,
Volume and Issue:
462, P. 214508 - 214508
Published: March 29, 2022
The
cell
contains
various
organelles
that
perform
different
functions
using
biological
processes
to
form
a
complete
organic
architecture.
Healthy
cells
and
tumor
often
show
clear
differences
in
cellular
homeostasis.
Specific
detection,
imaging,
therapeutic
strategies
targeting
have
been
found
be
effective
for
diagnosis
therapy.
multiple
of
AIEgens
make
them
attractive
over
other
nanomaterials,
the
application
has
increased
dramatically
tumor-related
nanomedicine,
specifically,
bioimaging,
therapy
cancers.
Here,
recent
advances
AIEgen
applications
specific
are
summarized.
ability
target
enhanced
diagnostic
this
technology,
review
will
provide
guidance
further
exploration
AIEgen-related
nanomedicine.
Advanced Optical Materials,
Journal Year:
2023,
Volume and Issue:
11(12)
Published: April 9, 2023
Abstract
The
understanding
of
the
excited
state
dynamics
thermally
activated
delayed
fluorescence
(TADF)
materials
is
crucial.
In
this
study,
two
donor–acceptor‐type
TADF
emitters
with
highly
twisted
conformation
are
synthesized.
subtle
chemical
modification
donor
unit
exhibit
opposite
aggregation
luminescent
behaviors:
aggregation‐induced
emission
(AIE)
and
aggregation‐caused
quenching
(ACQ).
Through
photophysical
properties
crystallographic
analysis,
theory
simulations,
it
discovered
that
X‐aggregation
supports
AIE
behavior
by
restricting
intramolecular
motions
preserving
via
an
efficient
reverse
intersystem
crossing
(RISC)
process,
but
on
other
hand,
H‐aggregation
leads
to
ACQ
due
inhibited
RISC,
disabled
channel,
weak
phosphorescence
from
radiative
low‐lying
triplet
state.
findings
shed
light
excited‐state
dynamic
behaviors
emitters,
which
dependent
aggregation.
Nano Letters,
Journal Year:
2024,
Volume and Issue:
24(10), P. 3005 - 3013
Published: Feb. 28, 2024
Most
aggregation-induced
emission
(AIE)
luminogens
exhibit
high
brightness,
excellent
photostability,
and
good
biocompatibility,
but
these
AIE-active
agents,
which
kill
two
birds
with
one
stone
to
result
in
applications
both
stimulated
depletion
(STED)
super-resolution
imaging
photodynamic
therapy
(PDT),
have
not
been
reported
yet
are
urgently
needed.
To
meet
the
requirements
of
STED
nanoscopy
PDT,
D-A-π-A-D
type
DTPABT-HP
is
designed
by
tuning
conjugated
π
spacers.
It
exhibits
red-shifted
emission,
PLQY
32.04%,
impressive
1O2
generation
(9.24
fold
compared
RB)
nanoparticles
(NPs).
Then,
NPs
applied
cell
via
nanoscopy,
especially
visualizing
dynamic
changes
lysosomes
PDT
process
at
ultrahigh
resolution.
After
that,
vivo
was
also
conducted
NPs,
resulting
significantly
inhibited
tumor
growth,
an
inhibition
rate
86%.
The
work
here
beneficial
design
multifunctional
agents
deep
understanding
their
phototheranostic
mechanism
biological
research.
Chemical Science,
Journal Year:
2024,
Volume and Issue:
15(19), P. 7178 - 7186
Published: Jan. 1, 2024
Through
the
formation
of
macrocycle
and
[2]catenane,
precise
regulation
vibration-induced
emission
has
been
successfully
achieved,
providing
a
new
strategy
for
development
novel
molecular
systems
with
tunable
behaviors.
Chemical Science,
Journal Year:
2021,
Volume and Issue:
13(5), P. 1270 - 1280
Published: Dec. 13, 2021
AIE
nanocrystals
with
high
brightness
in
the
deep-red
region
were
facilely
prepared
by
kinetically
controlled
nanoprecipitation.
These
then
applied
super-resolution
cellular
imaging
via
STED
nanoscopy.
Coordination Chemistry Reviews,
Journal Year:
2022,
Volume and Issue:
462, P. 214508 - 214508
Published: March 29, 2022
The
cell
contains
various
organelles
that
perform
different
functions
using
biological
processes
to
form
a
complete
organic
architecture.
Healthy
cells
and
tumor
often
show
clear
differences
in
cellular
homeostasis.
Specific
detection,
imaging,
therapeutic
strategies
targeting
have
been
found
be
effective
for
diagnosis
therapy.
multiple
of
AIEgens
make
them
attractive
over
other
nanomaterials,
the
application
has
increased
dramatically
tumor-related
nanomedicine,
specifically,
bioimaging,
therapy
cancers.
Here,
recent
advances
AIEgen
applications
specific
are
summarized.
ability
target
enhanced
diagnostic
this
technology,
review
will
provide
guidance
further
exploration
AIEgen-related
nanomedicine.
