α-Diazoesters
belong
to
significantly
important
carbenoid
precursors
in
synthetic
chemistry,
diazomethylation-based
difunctionalization
of
alkenes
is
highly
valuable
but
remain
nontrivial.
Herein,
we
reported
a
general
and
modular
approach
for
the
direct
1,2-hydroxyl-diazomethylation
through
visible-light
photoredox
catalysis.
This
process
exploits
photocatalyzed
strategy
convert
γ-hydroxyl-α-diazoesters
using
α-diazo
iodonium
salts
as
carbyne
precursors,
featuring
wide
substrate
tolerance
broad
late-stage
diversifications.
Mechanistic
studies
suggest
that
formation
γ-carbocation-tethered
α-diazoesters
plays
crucial
role
trapping
H2O
allow
this
transformation.
Energy & Fuels,
Journal Year:
2023,
Volume and Issue:
37(17), P. 12589 - 12622
Published: Aug. 10, 2023
Rapid
advancements
in
renewable
energy
and
the
staggering
environmental
impact
of
ethylene
production
have
made
quest
for
"green
ethylene"
urgent.
This
Review
explores
traditional
emerging
methods
production,
focusing
on
transition
from
conventional
to
electrified
processes.
The
global
importance
industry,
valued
at
$230
billion,
cannot
be
overlooked.
However,
its
significant
contribution
150
million
t
annual
CO2
emissions
necessitates
adopting
carbon-negative
sustainable
approaches.
declining
cost
has
sparked
interest
processes,
including
electric
crackers
electrochemical
reactors
production.
provides
a
balanced
overview
performance
attributes
reactors,
such
as
conversion,
selectivity,
operating
temperatures,
crucial
features
Faradaic
efficiency
current
density.
Operating
poses
their
own
challenges,
corrosion
lower
efficiencies,
which
are
discussed
detail.
also
examines
economic
aspects
identifying
challenges
opportunities.
A
comprehensive
roadmap
is
presented
meet
scale
green
ethylene.
outlines
steps
needed
ensuring
environmentally
friendly
future
In
summary,
we
emphasize
urgent
need
provide
pathways
insights
into
different
discusses
presents
an
analysis.
Journal of Catalysis,
Journal Year:
2024,
Volume and Issue:
432, P. 115397 - 115397
Published: March 1, 2024
Carbonylation
reactions
carried
out
at
room
temperature
and
atmospheric
pressure
of
carbon
monoxide
are
highly
attractive
extremely
rare
the
same
time.
Here,
oxidative
alkoxycarbonylation
styrenes
to
industrially
relevant
cinnamates
has
been
developed
under
such
a
mild
conditions
(rt,
1
atm
CO)
in
presence
palladium(II)
complex
bearing
bis(aryl)acenaphthenequinonediimine
ligand,
benzoquinone
p-toluenesulfonic
acid.
Remarkably,
variously
substituted
styrene
derivatives
have
efficiently
carbonylated
using
nearly
stoichiometric
amount
alcohols,
with
dramatic
reduction
waste.
Even
reluctant
internal
alkenes
shown
be
compatible
these
carbonylative
conditions.
In
consideration
experimental
results
DFT
calculations
mechanistic
rationale
proposed.
Based
on
this
study,
found
promote
final
palladium
reoxidation,
boost
reaction
unprecedent
The
present
methodology
successfully
exploited
for
synthesis
high
value-added
cinnamoyl
glycerols
cinnamic
acid
sugar
esters,
including
6-O-p-coumaroyl-D-glucose
natural
product.
Green Carbon,
Journal Year:
2024,
Volume and Issue:
2(2), P. 205 - 208
Published: April 2, 2024
Employing
biodegradable
plastics
is
one
of
the
choices
to
solve
white
pollution
issues.
PBS
(polybutylene
succinate),
as
a
plastic
with
good
stability
and
heat
resistance,
produced
by
polymerization
succinic
acid
butylene
glycol.
However,
inadequate
supply
direct
upstream
material
restricts
development
this
industry.
In
work,
we
provide
carbonylative
strategy
construct
derivatives
from
carbon
monoxide,
ethylene
alcohols.
The
reaction
catalyzed
palladium
catalyst
under
oxidative
conditions.
Chemical Science,
Journal Year:
2023,
Volume and Issue:
15(4), P. 1418 - 1423
Published: Dec. 14, 2023
Difunctionalization
of
alkenes
is
an
efficient
strategy
for
the
synthesis
complex
compounds
from
readily
available
starting
materials.
Herein,
we
developed
a
copper-catalyzed
visible-light-mediated
trichloromethylative
carbonylation
ethylene
by
employing
commercially
CCl
The Chemical Record,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 3, 2025
Abstract
Owing
to
their
wide
utilizations
in
synthesis
and
products
prevalence
numerous
natural
products,
pharmaceuticals
functional
materials,
the
alkene
difunctionalization
methods
for
selective
transformations
of
olefins
are
important
have
attracted
much
attention
form
synthetic
chemists.
Among
them,
electrochemical
reaction
is
particularly
promising
has
becoming
a
potent
sustainable
tool
alkenes
into
vicinal
difunctionalized
structures
organic
through
simultaneous
incorporation
two
groups.
Herein,
we
summarize
recent
progress
reactions
according
types
as
well
category
radicals
over
past
five
years.
By
selecting
remarkable
examples,
elaborately
discussed
substrate
scope
mechanisms
olefin
reaction.
Chemical Communications,
Journal Year:
2023,
Volume and Issue:
59(89), P. 13309 - 13312
Published: Jan. 1, 2023
This
study
describes
an
iron-catalyzed
divergent
oxidation
of
styrene
into
β-hydroxylmethylketone
and
ketone
under
photo-irradiation.
divergence
is
ascribed
to
the
use
with
various
substituents.
More
importantly,
methanol
oxidized
formaldehyde
in
reaction
serves
as
a
C1
synthon.
Mechanism
investigations
show
that
initiated
by
oxidative
SET
transfer
cation
radical.
The
pathway
undergoes
HAT
β-hydride
elimination
well
concerted
cyclization.
Particularly,
several
drug-like
molecules,
such
melperone
analogue,
lenperone
haloperidol
are
synthesized.
In
addition,
this
method
also
applicable
synthesis
natural
product
(R)-atomoxetine.
Chemistry - A European Journal,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 12, 2024
α-Diazoesters
belong
to
significantly
important
carbenoid
precursors
in
synthetic
chemistry.
Diazomethylation-based
difunctionalization
of
alkenes
is
highly
valuable
but
remain
nontrivial.
Herein,
we
reported
a
general
and
modular
approach
for
the
direct
1,2-oxydiazomethylation
through
visible-light
photoredox
catalysis.
This
process
exploits
photocatalyzed
strategy
convert
γ-formyloxyl-α-diazoesters
using
α-diazo
iodonium
salts
as
carbyne
precursors,
featuring
wide
substrate
tolerance
broad
late-stage
diversifications.
Mechanistic
studies
suggest
that
formation
γ-carbocation-tethered
α-diazoesters
plays
crucial
role
trapping
DMF
H
