An Innovative Near-Infrared Fluorescent Probe for the Continuous Detection of Zn2+ and PPI, and its Applications in Biological Imaging and Real Samples DOI

Qingbiao Yang,

Yixuan Yao,

Fudong Zeng

et al.

Published: Jan. 1, 2023

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Language: Английский

Photonic control of image-guided ferroptosis cancer nanomedicine DOI Creative Commons
Min Jun Ko, Woojung Yoo, Sunhong Min

et al.

Coordination Chemistry Reviews, Journal Year: 2023, Volume and Issue: 500, P. 215532 - 215532

Published: Nov. 10, 2023

Language: Английский

Citations

25
A Fluorescent Probe with Large Stokes Shift for Detecting Biothiols in Living Cells and Zebrafish DOI
Zhao Wang, Zhenbo Gao, Yue Gao

et al.

Tetrahedron, Journal Year: 2025, Volume and Issue: unknown, P. 134615 - 134615

Published: March 1, 2025

Language: Английский

Citations

1
Real-time monitoring of endogenous cysteine in LPS-induced oxidative stress process with a novel lysosome-targeted fluorescent probe DOI
Zhiqiang Yang, Jia Li, Sining Li

et al.

Analytica Chimica Acta, Journal Year: 2023, Volume and Issue: 1279, P. 341819 - 341819

Published: Sept. 13, 2023

Language: Английский

Citations

18
Unveiling regularities of B12N12-X nanocages as a drug delivery vehicle for the nitrosourea: The influence of periods and groups DOI
Y.B. Zhang, Yafei Luo, Lingkai Tang

et al.

Journal of Molecular Liquids, Journal Year: 2023, Volume and Issue: 393, P. 123607 - 123607

Published: Nov. 15, 2023

Language: Английский

Citations

12
Fabrication of a Redox-Reversible Near-Infrared Fluorogenic Probe for Ferroptosis Process Monitoring and the Early Diagnosis of Diabetes DOI
Le He, Wei Xiao, Wei Zhang

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 21, 2025

Ferroptosis is a type of cell death triggered by the iron-dependent accumulation lipid peroxides in cells. Diabetes, chronic metabolic disorder characterized hyperglycemia, can lead to various health complications. The process ferroptosis and progression diabetes are closely linked redox homeostasis, which regulated levels reactive oxygen sulfur species. Currently, there no fluorescent probes available monitor changes homeostasis during diabetes. Here, we report first endeavor create reversible near-infrared fluorogenic (NIRF) probe for monitoring reversal precise diagnosis. In vitro data demonstrated that NIR-CSTe could cyclically reversibly detect ONOO- GSH up four times with minimal loss fluorescence intensity. With help NIR-CSTe, observed HT-1080 cells, induced undergo erastin after being washed PBS 24 h then treated ferrostatin-1, showed recovery intracellular levels. contrast, treatment deferoxamine did not yield similar results. Lastly, was also utilized early diagnosis efficacy assessment relation ONOO-/GSH balance, results illustrating combined administration metformin empagliflozin more effective than using either drug alone. Thus, this smart holds significant potential as an essential tool clinical diseases associated homeostasis.

Language: Английский

Citations

0
Recent developments of small-molecule fluorescent probes for the detection of hydroxyl radical in biological systems DOI
Shanshan Zhang, Heejeong Kim,

Yongqing Zhou

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 118165 - 118165

Published: Feb. 1, 2025

Language: Английский

Citations

0
Harnessing the power of nanoagents in acute kidney injury: A versatile platform for imaging and treatment DOI
Peng Liu, Yu Zhao, Ying Peng

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 533, P. 216570 - 216570

Published: Feb. 27, 2025

Language: Английский

Citations

0
Advances on fluorescence bioimaging and photo-mediated therapy of NIR-II small molecule dyes DOI
Weijie Zhang,

Laraib,

Fangjun Huo

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 534, P. 216587 - 216587

Published: March 14, 2025

Language: Английский

Citations

0
Protein‐Interference‐Free and Kidney‐Targeting NIR Fluorophores for Accurate in Vivo Imaging of H2S2 during Kidney Ferroptosis DOI Open Access

Zhangkang Lv,

Jing Wang,

Jinyuan Xu

et al.

Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown

Published: March 24, 2025

High-fidelity kidney function imaging is important for assessing the nephrotoxicity of drugs and diagnosing renal diseases. However, current challenges in achieving accurate include unspecific signal enhancement due to albumin binding relatively low distribution agents kidneys. Here, first time, a side-chain engineering strategy that incorporates hydrophilic six-membered heterocycles into aza-hemicyanine generating high-performance with protein-interference-free kidney-targeting features proposed. Based on these unique dyes, albumin-insensitive H2S2 near-infrared (NIR) fluorescent probe NA-H2S2 designed, which demonstrates effective following intravenous injection specifically activated by H2S2. The designed presents highly rapid, selective sensitive response detection limit as 24.21 nm. Additionally, it successfully achieves real-time vivo NIR fluorescence during erastin/cisplatin induced ferroptosis. Moreover, also enables rapid through vitro optical urinalysis, offering significant diagnostic value Overall, this study not only practical increased accuracy but provides promising dyes further development disease-related probes.

Language: Английский

Citations

0
Stimuli-responsive smart nanomaterials for theranostics of urological cancers DOI

Yi Xu,

Madineh Moradialvand, Francesca Della Sala

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 539, P. 216745 - 216745

Published: May 1, 2025

Language: Английский

Citations

0