Emerging Piezoelectric Sonosensitizer for ROS-Driven Sonodynamic Cancer Therapy

Inorganics, Journal Year: 2025, Volume and Issue: 13(3), P. 71 - 71

Published: Feb. 26, 2025

As a non-invasive modality, sonodynamic therapy (SDT) offers several advantages in cancer treatment, including deep tissue penetration and precise spatiotemporal control, resulting from the interplay between low-intensity ultrasound sonosensitizers. Piezoelectric materials, known for their remarkable capacity of interconversion mechanical electrical energy, have garnered considerable attention biomedical applications, which can serve as pivotal sonosensitizers SDT. These materials generate internal electric fields via ultrasound-induced deformation, modulates alteration charge carriers, thereby initiating surface redox reactions to reactive oxygen species (ROS) realizing therapeutic efficacy This review provides an in-depth exploration piezoelectric utilized SDT, with particular emphasis on recent innovations, elucidation underlying mechanisms, optimization strategies advanced materials. Furthermore, incorporation immunotherapy, photodynamic, chemodynamic, chemotherapy is explored, emphasizing potential enhance outcomes. By examining basic principles effect its contributions this sheds light promising applications oncology. It also highlights future directions improving these expanding clinical utility tumor therapy.

Language: Английский

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Advancement in tribological performance of hexagonal Bi2Te3 nanosheets by incorporation of Ag2MoO4 nanoparticles

Hybrid Advances, Journal Year: 2025, Volume and Issue: unknown, P. 100429 - 100429

Published: March 1, 2025

Language: Английский

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Safe-by-design strategies towards bismuth-based nanomaterials in tumor diagnosis and therapy

Nano Today, Journal Year: 2025, Volume and Issue: 62, P. 102714 - 102714

Published: March 15, 2025

Language: Английский

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Nanoarchitectured bismuth-based structures for diverse applications: Recent advancements and latest breakthroughs

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 536, P. 216645 - 216645

Published: April 4, 2025

Language: Английский

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Bismuth Oxyhalides (BiOX (X=Cl, Br, I)) based composites for photocatalytic antibacterial: Modification strategies, antibacterial mechanisms and prospects

Journal of environmental chemical engineering, Journal Year: 2025, Volume and Issue: unknown, P. 116428 - 116428

Published: April 1, 2025

Language: Английский

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P–N Type ReS₂/Cu₂O Nanoheterojunction for Sonodynamic and Chemodynamic Tumor Therapy

ACS Applied Nano Materials, Journal Year: 2025, Volume and Issue: unknown

Published: April 27, 2025

Language: Английский

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Polyimide/CNTs Ionogel for Application in Photo‐Thermal‐Resistance Response Materials

Journal of Applied Polymer Science, Journal Year: 2025, Volume and Issue: unknown

Published: May 11, 2025

ABSTRACT Ionogels have inherent ionic conductivity, flexibility, and excellent mechanical properties, which received increasing attention for their use as transducers, flexible devices, optoelectronic sensing applications. However, the reported photo‐thermal‐resistance responsible ionogels are hindered by weak low narrow working temperature range, inefficient response efficiency. Here, polyimide (PI) were doped with carbon nanotubes (CNTs) to obtain PI/CNTs (PI/CNTs‐IG). The resulting PI/CNTs‐IG exhibits properties (tensile strength ~3.9 MPa, elongation at break ~260%), high thermal stability (~300°C), conductivity (8.1–9.8 mS/cm) fast response, can be used high‐performance responsive materials meet demand highly stable in a wide application range.

Language: Английский

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Sulfonated polyetheretherketone enriched with MXene V2C promotes bone formation via WNT/β-catenin signaling in bone marrow mesenchymal stem cells

Medical Engineering & Physics, Journal Year: 2025, Volume and Issue: unknown, P. 104361 - 104361

Published: May 1, 2025

Language: Английский

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Single-crystal structure feature of a new polymer based on Bi(III) as an antibacterial agent

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 142699 - 142699

Published: May 1, 2025

Language: Английский

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Biodegradable Bismuth Nanostructures as a Ferroptosis Inducer for Phototherapy of Breast Cancer

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: 7(12), P. 14406 - 14418

Published: June 7, 2024

The therapeutic efficacy of monotherapy on tumors is often limited due to the constraints tumor response conditions, significantly impacting clinical treatment outcomes. In this study, we design a collaborative nanosystem (BBSP) that combines photodynamic therapy (PDT) and photothermal (PTT). system formulated by doping sulfur ions modulate wide band gap BiF3 semiconductor nanospheres. introduction its combination with bismuth not only enhance light absorption but also introduce oxygen vacancies local surface plasmon resonance effect bismuth. Compared BiF3, reduced carrier separation efficiency improved. Under irradiation 520 nm laser, electrons reduce in process transition meanwhile give energy O2, producing large number reactive species (ROS). Simultaneously, holes valence oxidize glutathione (GSH), coordination ion GSH further depletes GSH. RNA sequencing results reveal downregulation GPX4 cells, inducing ferroptosis. Additionally, sulfide augmented absorption, synergizing heat, thereby increasing oxidative damage inhibiting growth. BBSP emerges as promising strategy for treatment, orchestrating ferroptosis apoptosis through combined application PDT PTT.

Language: Английский

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